diff --git a/.azure/docs-linux.yml b/.azure/docs-linux.yml
index 4f1f9206a11c..0f8e3015c0eb 100644
--- a/.azure/docs-linux.yml
+++ b/.azure/docs-linux.yml
@@ -30,8 +30,8 @@ jobs:
 
       - bash: |
           set -e
-          python -m pip install --upgrade pip setuptools wheel
-          pip install -U tox
+          python -m pip install --upgrade pip 'setuptools<64.0.0' wheel -c constraints.txt
+          pip install -U tox -c constraints.txt
           sudo apt-get update
           sudo apt-get install -y graphviz
         displayName: 'Install dependencies'
@@ -39,6 +39,8 @@ jobs:
       - bash: |
           tox -edocs
         displayName: 'Run Docs build'
+        env:
+          SETUPTOOLS_ENABLE_FEATURES: "legacy-editable"
 
       - task: ArchiveFiles@2
         inputs:
diff --git a/.azure/lint-linux.yml b/.azure/lint-linux.yml
index 830acdc1821e..5fddd6afef3f 100644
--- a/.azure/lint-linux.yml
+++ b/.azure/lint-linux.yml
@@ -28,7 +28,7 @@ jobs:
 
       - bash: |
           set -e
-          python -m pip install --upgrade pip setuptools wheel virtualenv
+          python -m pip install --upgrade pip 'setuptools<64.0.0' wheel virtualenv -c constraints.txt
           virtualenv test-job
           source test-job/bin/activate
           pip install -U -r requirements.txt -r requirements-dev.txt -c constraints.txt
@@ -36,6 +36,8 @@ jobs:
           pip install -U "qiskit-aer" -c constraints.txt
           python setup.py build_ext --inplace
         displayName: 'Install dependencies'
+        env:
+          SETUPTOOLS_ENABLE_FEATURES: "legacy-editable"
 
       - bash: |
           set -e
diff --git a/.azure/test-linux.yml b/.azure/test-linux.yml
index 6389dafc8604..14d1c090f822 100644
--- a/.azure/test-linux.yml
+++ b/.azure/test-linux.yml
@@ -62,7 +62,7 @@ jobs:
 
       - bash: |
           set -e
-          python -m pip install --upgrade pip setuptools wheel virtualenv
+          python -m pip install --upgrade pip 'setuptools<64.0.0' wheel virtualenv -c constraints.txt
           virtualenv test-job
         displayName: "Prepare venv"
 
@@ -82,6 +82,9 @@ jobs:
             pip install -U -r requirements.txt -r requirements-dev.txt -c constraints.txt
             pip install -U -c constraints.txt -e .
           displayName: "Install Terra directly"
+          env:
+            SETUPTOOLS_ENABLE_FEATURES: "legacy-editable"
+
 
       - bash: |
           set -e
@@ -165,6 +168,8 @@ jobs:
             sudo apt-get install -y graphviz pandoc
             image_tests/bin/pip check
           displayName: 'Install dependencies'
+          env:
+            SETUPTOOLS_ENABLE_FEATURES: "legacy-editable"
 
         - bash: image_tests/bin/python -m unittest discover -v test/ipynb
           displayName: 'Run image test'
diff --git a/.azure/test-macos.yml b/.azure/test-macos.yml
index c0e05f4990ff..4417dd8add68 100644
--- a/.azure/test-macos.yml
+++ b/.azure/test-macos.yml
@@ -41,7 +41,7 @@ jobs:
 
       - bash: |
           set -e
-          python -m pip install --upgrade pip setuptools wheel virtualenv
+          python -m pip install --upgrade pip 'setuptools<64.0.0' wheel virtualenv -c constraints.txt
           virtualenv test-job
           source test-job/bin/activate
           pip install -U -r requirements.txt -r requirements-dev.txt -c constraints.txt
@@ -49,6 +49,8 @@ jobs:
           python setup.py build_ext --inplace
           pip check
         displayName: 'Install dependencies'
+        env:
+          SETUPTOOLS_ENABLE_FEATURES: "legacy-editable"
 
       - bash: |
           set -e
diff --git a/.azure/test-windows.yml b/.azure/test-windows.yml
index 9bac8b2683bf..8140a6ce4fbb 100644
--- a/.azure/test-windows.yml
+++ b/.azure/test-windows.yml
@@ -30,7 +30,7 @@ jobs:
 
       - bash: |
           set -e
-          python -m pip install --upgrade pip setuptools wheel virtualenv
+          python -m pip install --upgrade pip 'setuptools<64.0.0' wheel virtualenv -c constraints.txt
           virtualenv test-job
           source test-job/Scripts/activate
           pip install -r requirements.txt -r requirements-dev.txt -c constraints.txt
@@ -39,6 +39,8 @@ jobs:
           python setup.py build_ext --inplace
           pip check
         displayName: 'Install dependencies'
+        env:
+          SETUPTOOLS_ENABLE_FEATURES: "legacy-editable"
 
       - bash: |
           set -e
diff --git a/.azure/tutorials-linux.yml b/.azure/tutorials-linux.yml
index 03eac35bc193..2ce7cb9026c8 100644
--- a/.azure/tutorials-linux.yml
+++ b/.azure/tutorials-linux.yml
@@ -39,6 +39,8 @@ jobs:
           sudo apt-get install -y graphviz pandoc
           pip check
         displayName: 'Install dependencies'
+        env:
+          SETUPTOOLS_ENABLE_FEATURES: "legacy-editable"
 
       - bash: |
           set -e
diff --git a/.github/workflows/coverage.yml b/.github/workflows/coverage.yml
index 6e149a0d39c7..08861cb1def9 100644
--- a/.github/workflows/coverage.yml
+++ b/.github/workflows/coverage.yml
@@ -20,6 +20,8 @@ jobs:
         run: pip install tox coveragepy-lcov
       - name: Run coverage report
         run: tox -ecoverage
+        env:
+          SETUPTOOLS_ENABLE_FEATURES: "legacy-editable"
       - name: Convert to lcov
         run: coveragepy-lcov --output_file_path coveralls.info
       - name: Coveralls
diff --git a/.github/workflows/randomized_tests.yml b/.github/workflows/randomized_tests.yml
index 5465e499b105..f96f84e0ed78 100644
--- a/.github/workflows/randomized_tests.yml
+++ b/.github/workflows/randomized_tests.yml
@@ -20,6 +20,8 @@ jobs:
           pip install -c constraints.txt -e .
           pip install "qiskit-ibmq-provider" -c constraints.txt
           pip install "qiskit-aer"
+        env:
+          SETUPTOOLS_ENABLE_FEATURES: "legacy-editable"
       - name: Run randomized tests
         run: make test_randomized
       - name: Create comment on failed test run
diff --git a/constraints.txt b/constraints.txt
index 3cb8598cb345..bf4e304596c5 100644
--- a/constraints.txt
+++ b/constraints.txt
@@ -13,3 +13,7 @@ pyparsing<3.0.0
 # to work with the new jinja version (the jinja maintainers aren't going to
 # fix things) pin to the previous working version.
 jinja2==3.0.3
+
+# setuptools 64.0.0 breaks editable installs. Pin to an old version until
+# see https://github.com/pypa/setuptools/issues/3498
+setuptools==63.3.0
diff --git a/pyproject.toml b/pyproject.toml
index 9282c3b8c8d0..728e2a2be55a 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -1,5 +1,5 @@
 [build-system]
-requires = ["setuptools", "wheel", "setuptools-rust"]
+requires = ["setuptools", "wheel", "setuptools-rust<1.5.0"]
 build-backend = "setuptools.build_meta"
 
 [tool.black]
diff --git a/requirements-dev.txt b/requirements-dev.txt
index eef50c6b96e1..fb5e2cbeae18 100644
--- a/requirements-dev.txt
+++ b/requirements-dev.txt
@@ -1,4 +1,4 @@
-setuptools-rust
+setuptools-rust<1.5.0
 coverage>=4.4.0
 hypothesis>=4.24.3
 python-constraint>=1.4
diff --git a/tox.ini b/tox.ini
index f457cab047e0..0561b10732a7 100644
--- a/tox.ini
+++ b/tox.ini
@@ -14,7 +14,7 @@ setenv =
   QISKIT_SUPRESS_PACKAGING_WARNINGS=Y
   QISKIT_TEST_CAPTURE_STREAMS=1
   QISKIT_PARALLEL=FALSE
-passenv = RAYON_NUM_THREADS OMP_NUM_THREADS QISKIT_PARALLEL
+passenv = RAYON_NUM_THREADS OMP_NUM_THREADS QISKIT_PARALLEL SETUPTOOLS_ENABLE_FEATURES
 deps = -r{toxinidir}/requirements.txt
        -r{toxinidir}/requirements-dev.txt
 commands =