diff --git a/pxr/base/tf/diagnosticBase.h b/pxr/base/tf/diagnosticBase.h
index c14d416909..72014beb31 100644
--- a/pxr/base/tf/diagnosticBase.h
+++ b/pxr/base/tf/diagnosticBase.h
@@ -38,13 +38,13 @@
 #include "pxr/base/arch/attributes.h"
 #include "pxr/base/arch/function.h"
 
-#include <boost/any.hpp>
+#include <any>
 #include <cstdarg>
 #include <string>
 
 PXR_NAMESPACE_OPEN_SCOPE
 
-typedef boost::any TfDiagnosticInfo;
+typedef std::any TfDiagnosticInfo;
 
 class TfDiagnosticMgr;
 
@@ -160,7 +160,7 @@ class TfDiagnosticBase {
     /// then GetInfo() returns NULL.
     template <typename T>
     const T* GetInfo() const {
-        return boost::any_cast<T>(&_info);
+        return std::any_cast<T>(&_info);
     }
 
     /// Set the info object associated with this diagnostic message.
diff --git a/pxr/base/tf/diagnosticHelper.h b/pxr/base/tf/diagnosticHelper.h
index f4c6b1592a..2552c1fab6 100644
--- a/pxr/base/tf/diagnosticHelper.h
+++ b/pxr/base/tf/diagnosticHelper.h
@@ -32,12 +32,12 @@
 // incompatible macro definitions in pyport.h on macOS.
 #include <locale>
 
-#include <boost/any.hpp>
+#include <any>
 #include <string>
 
 PXR_NAMESPACE_OPEN_SCOPE
 
-typedef boost::any TfDiagnosticInfo;
+typedef std::any TfDiagnosticInfo;
 class TfCallContext;
 enum TfDiagnosticType : int;
 class TfEnum;
diff --git a/pxr/base/tf/diagnosticMgr.cpp b/pxr/base/tf/diagnosticMgr.cpp
index e42acffd56..5e9e48dbb8 100644
--- a/pxr/base/tf/diagnosticMgr.cpp
+++ b/pxr/base/tf/diagnosticMgr.cpp
@@ -42,11 +42,10 @@
 #include "pxr/base/arch/stackTrace.h"
 #include "pxr/base/arch/threads.h"
 
-#include <boost/utility.hpp>
-
 #include <signal.h>
 #include <stdlib.h>
 
+#include <any>
 #include <thread>
 #include <memory>
 
@@ -673,7 +672,7 @@ TfDiagnosticMgr::FormatDiagnostic(const TfEnum &code,
 
 #ifdef PXR_PYTHON_SUPPORT_ENABLED
     if (const TfPyExceptionState* exc =
-            boost::any_cast<TfPyExceptionState>(&info)) {
+            std::any_cast<TfPyExceptionState>(&info)) {
         output += TfStringPrintf("%s\n", exc->GetExceptionString().c_str());
     }
 #endif // PXR_PYTHON_SUPPORT_ENABLED