diff --git a/parsl/executors/high_throughput/errors.py b/parsl/executors/high_throughput/errors.py
index 4db7907523..9916ec506f 100644
--- a/parsl/executors/high_throughput/errors.py
+++ b/parsl/executors/high_throughput/errors.py
@@ -1,3 +1,36 @@
+import time
+
+
+class ManagerLost(Exception):
+    """
+    Task lost due to manager loss.  Manager is considered lost when multiple heartbeats
+    have been missed.
+    """
+    def __init__(self, manager_id: bytes, hostname: str) -> None:
+        self.manager_id = manager_id
+        self.tstamp = time.time()
+        self.hostname = hostname
+
+    def __str__(self) -> str:
+        return (
+            f"Task failure due to loss of manager {self.manager_id.decode()} on"
+            f" host {self.hostname}"
+        )
+
+
+class VersionMismatch(Exception):
+    """Manager and Interchange versions do not match"""
+    def __init__(self, interchange_version: str, manager_version: str):
+        self.interchange_version = interchange_version
+        self.manager_version = manager_version
+
+    def __str__(self) -> str:
+        return (
+            f"Manager version info {self.manager_version} does not match interchange"
+            f" version info {self.interchange_version}, causing a critical failure"
+        )
+
+
 class WorkerLost(Exception):
     """Exception raised when a worker is lost
     """
diff --git a/parsl/executors/high_throughput/interchange.py b/parsl/executors/high_throughput/interchange.py
index 9fe94dbabd..819836e95f 100644
--- a/parsl/executors/high_throughput/interchange.py
+++ b/parsl/executors/high_throughput/interchange.py
@@ -17,6 +17,7 @@
 
 from parsl import curvezmq
 from parsl.app.errors import RemoteExceptionWrapper
+from parsl.executors.high_throughput.errors import ManagerLost, VersionMismatch
 from parsl.executors.high_throughput.manager_record import ManagerRecord
 from parsl.monitoring.message_type import MessageType
 from parsl.process_loggers import wrap_with_logs
@@ -31,32 +32,6 @@
 logger = logging.getLogger(LOGGER_NAME)
 
 
-class ManagerLost(Exception):
-    ''' Task lost due to manager loss. Manager is considered lost when multiple heartbeats
-    have been missed.
-    '''
-    def __init__(self, manager_id: bytes, hostname: str) -> None:
-        self.manager_id = manager_id
-        self.tstamp = time.time()
-        self.hostname = hostname
-
-    def __str__(self) -> str:
-        return "Task failure due to loss of manager {} on host {}".format(self.manager_id.decode(), self.hostname)
-
-
-class VersionMismatch(Exception):
-    ''' Manager and Interchange versions do not match
-    '''
-    def __init__(self, interchange_version: str, manager_version: str):
-        self.interchange_version = interchange_version
-        self.manager_version = manager_version
-
-    def __str__(self) -> str:
-        return "Manager version info {} does not match interchange version info {}, causing a critical failure".format(
-            self.manager_version,
-            self.interchange_version)
-
-
 class Interchange:
     """ Interchange is a task orchestrator for distributed systems.
 
diff --git a/parsl/tests/test_serialization/test_3495_deserialize_managerlost.py b/parsl/tests/test_serialization/test_3495_deserialize_managerlost.py
new file mode 100644
index 0000000000..3d35b110c2
--- /dev/null
+++ b/parsl/tests/test_serialization/test_3495_deserialize_managerlost.py
@@ -0,0 +1,47 @@
+import os
+import signal
+
+import pytest
+
+import parsl
+from parsl import Config, HighThroughputExecutor
+
+
+@parsl.python_app
+def get_manager_pgid():
+    import os
+    return os.getpgid(os.getpid())
+
+
+@parsl.python_app
+def lose_manager():
+    import os
+    import signal
+
+    manager_pid = os.getppid()
+    os.kill(manager_pid, signal.SIGSTOP)
+
+
+@pytest.mark.local
+def test_manager_lost_system_failure(tmpd_cwd):
+    hte = HighThroughputExecutor(
+        label="htex_local",
+        address="127.0.0.1",
+        max_workers_per_node=2,
+        cores_per_worker=1,
+        worker_logdir_root=str(tmpd_cwd),
+        heartbeat_period=1,
+        heartbeat_threshold=1,
+    )
+    c = Config(executors=[hte], strategy='simple', strategy_period=0.1)
+
+    with parsl.load(c):
+        manager_pgid = get_manager_pgid().result()
+        try:
+            lose_manager().result()
+        except Exception as e:
+            assert "ManagerLost" not in str(e), f"Issue 3495: {e}"
+        finally:
+            # Allow process to clean itself up
+            os.killpg(manager_pgid, signal.SIGCONT)
+            os.killpg(manager_pgid, signal.SIGTERM)