Examples of when it is not possible to curate metagenotype controls

[CuzickA]

1. PMID:32883427 Functional evaluation of a homologue of plant rapid alkalinisation factor (RALF) peptides in Fusarium graminearum #89
   

also seen in paper #66

2. PMID: 31076860 A LysM effector protein from the basidiomycete Rhizoctonia solani contributes to virulence through suppression of chitin-triggered immunity. #44
   Can't curate controls as WT pathogen gene (delivered by infiltration or heterologous organism) on WT host with no specified gene
   The control for the ROS annotation (decreased level of pathogen-induced host reactive oxygen species) would be host only WT no specified gene +PTI = ROS present and we currently can't curate host genotype no specified gene.
   
   

[CuzickA]

3. Can't curate control metagenotypes as all metagenotypes are WT with natural variation. PMID:31246152 The Synchytrium endobioticum AvrSen1 Triggers a Hypersensitive Response in Sen1 Potatoes While Natural Variants Evade Detection. #65 AvrSen1 / Sen1 paper