Skip to content

Latest commit

 

History

History
83 lines (57 loc) · 2.49 KB

CHANGELOG.md

File metadata and controls

83 lines (57 loc) · 2.49 KB

Changelog

RELEASE 0.8.6 - Oct 28, 2024

Features

  • Enable parsing of a subset of CCDs from the Chemical Component Dictionary
  • Added CCDC to UniChem resources

RELEASE 0.8.5 - May 26, 2024

Features

  • Updated for RDKit 2023.09.6
  • Removed the formal charge adjustment for valence issues, instead uses Dative bonds
  • Uses Zero bond type (dotted lines) for depiction of coordinate bonds
  • Changes Dative bonds to single bonds for inchi calculation
  • Corrected the format of PDB files
  • Corrected the header of SDF file

Breaking changes

  • Removed smile from SubstructureMapping and added mol

RELEASE 0.8.0 - July 26, 2023

Features

  • Added clc_reader and clc_writer to read and write Covalently Linked Components (CLCs)
  • Added prd_reader and prd_writer to read and write Protein Reference Dictionarys (PRDs)
  • Added boundmolecule_cli, a pipeline to infer CLCs from PDB model files

RELEASE 0.7.0 - February 26, 2023

Features

  • Replaced pdbecif with gemmi for mmcif parsing
  • Support for rdkit 2022.09.x
  • Component representation of Covalently Linked Components (complex multi-component ligands typically represented as individual components represented by individual CCDs)

Breaking changes

  • Removed ccd_cif_dict (dict) property of Component. Please use ccd_cif_block (gemmi.cif.Block) to access data from mmcif file

RELEASE 0.6 - April 26, 2021

Features

  • A lot of minor bug fixes and code improvements
  • New templates for 2D layouts
  • Support for rdkit 2021.03.x

RELEASE 0.5 - May 15, 2019

Features

  • Add support for UniChem mapping.
  • Add bond information to the SVG decomposition.
  • Allow PARITY method to be atom/bond specific.
  • Improve and extend physchem properties.
  • Enhanced CIF export (physchem, scaffolds, fragments, 2D, mapping).
  • Few improvements to match newest RDKit version (breaking changes).

RELEASE 0.4 - January 12, 2019

Features

  • Add SVG decomposition in the SVG format.
  • Protein-ligand interaction pipeline moved to separate repository.
  • Add basic properties calculation (Abhik).
  • Extension and improvements of the Fragment library.

RELEASE 0.3 - October 12, 2018

Features

  • Introduce CoordGen from RDKit.
  • Refactored pdbeccdutils.core (breaking changes).
  • Scaffolding (Abhik).
  • Add protein-ligand interaction pipeline.

RELEASE 0.2 - June 14, 2018

Features

  • PDBeChem pipeline.
  • Support for PARITY method.
  • Introduce EKTGv2() method for 3D conformer generation.