Qualification plot: DDI Ratio

[Yuri05]

• 2 kinds of plots:
  • Predicted vs Observed
  • Residuals vs Observed (=Predicted/Observed vs Observed)
• Displaying 2-fold range and "Guest et al." range
• Simulations can be grouped

Predicted vs Observed	Residuals vs Observed

Example definition in qualification plan:

• plotType attributes defines which kind of the DDI Ratio plot should be created. Possible values:

  • predictedVsObserved
  • residualsVsObserved
  • predictedVsObserved|residualsVsObserved (:arrow_right: both plots must be produced using the same configuration)

• predicted PK parameters are calculated based on the time range [startTime .. endTime]. Time ranges can be defined independently for Simulation_control and Simulation_DDI

• PKparameter can be:

  • AUC
  • CMAX
  • AUC|CMAX (:arrow_right: both AUCR and CmaxR plots must be produced using the same configuration)
    • If one of the experimental values (AUCR OR CmaxR) is absent in the observed data set: omit the corresponding point in the plot (no warning)
    • If both AUCR and CmaxR are absent: warning

Definition in Report configuration: same as in qualification plan

The only change: observedDataType attribute is removed, because there is no distinction between INTERNAL and EXTERNAL observed data sets anymore, s. #15

[msevestre]

@Yuri05 Is this implemented? If yes can you close ? Also other issues? Trying so see what's left to do for the next report. Thanks

[Yuri05]

Already implemented. Closing