diff --git a/src/PKSim.Presentation/Views/Individuals/IExpressionParametersView.cs b/src/PKSim.Presentation/Views/Individuals/IExpressionParametersView.cs
index 742389402..6e90ee813 100644
--- a/src/PKSim.Presentation/Views/Individuals/IExpressionParametersView.cs
+++ b/src/PKSim.Presentation/Views/Individuals/IExpressionParametersView.cs
@@ -10,6 +10,6 @@ public interface IExpressionParametersView<TExpressionParameterDTO> : IView<IExp
    {
       void BindTo(IEnumerable<TExpressionParameterDTO> expressionParameters);
       bool EmphasisRelativeExpressionParameters { get; set; }
-      bool ReadOnly { set; }
+      bool ReadOnly { get; set; }
    }
 }
\ No newline at end of file
diff --git a/src/PKSim.UI/Views/Individuals/ExpressionParametersView.cs b/src/PKSim.UI/Views/Individuals/ExpressionParametersView.cs
index 1bd1a5c66..25ed2fe7c 100644
--- a/src/PKSim.UI/Views/Individuals/ExpressionParametersView.cs
+++ b/src/PKSim.UI/Views/Individuals/ExpressionParametersView.cs
@@ -48,6 +48,7 @@ public partial class ExpressionParametersView<TExpressionParameterDTO> : BaseUse
       public virtual bool ReadOnly
       {
          set => _colParameterValue.ReadOnly = value;
+         get => _colParameterValue.ReadOnly;
       }
 
       private readonly RepositoryItemProgressBar _progressBarRepository = new RepositoryItemProgressBar
@@ -62,7 +63,6 @@ public virtual bool ReadOnly
       private readonly ScreenBinder<IExpressionParametersPresenter<TExpressionParameterDTO>> _screenBinder =
          new ScreenBinder<IExpressionParametersPresenter<TExpressionParameterDTO>>();
 
-
       public ExpressionParametersView(IToolTipCreator toolTipCreator, IImageListRetriever imageListRetriever)
       {
          _toolTipCreator = toolTipCreator;
@@ -109,7 +109,7 @@ protected virtual bool ShouldMergeCell(GridColumn column, TExpressionParameterDT
       {
          //We only merge compartment values if they represent the same organ
          if (Equals(column, _colCompartment.XtraColumn))
-            return  representSameOrgan;
+            return representSameOrgan;
 
          return true;
       }
@@ -121,7 +121,7 @@ private void onShowingEditor(object sender, CancelEventArgs e)
 
          if (_gridView.FocusedColumn.ReadOnly)
             e.Cancel = true;
-         
+
          e.Cancel = !CanEditValueAt(_gridViewBinder.FocusedElement);
       }
 
@@ -238,7 +238,7 @@ protected void InitializeContainerBinding()
             .AsReadOnly();
 
 
-         _colCompartment= _gridViewBinder.AutoBind(item => item.CompartmentPathDTO)
+         _colCompartment = _gridViewBinder.AutoBind(item => item.CompartmentPathDTO)
             .WithRepository(dto => configureContainerRepository(dto.CompartmentPathDTO))
             .WithCaption(PKSimConstants.UI.Compartment)
             .AsReadOnly();
@@ -282,9 +282,11 @@ protected override bool ColumnIsValue(GridColumn gridColumn)
 
       private RepositoryItem repoForParameter(TExpressionParameterDTO expressionDTO)
       {
-         if (_presenter.IsSetByUser(expressionDTO.Parameter))
+         //Parameter changed by the user and the view in not readonly, we can show the update button
+         if (_presenter.IsSetByUser(expressionDTO.Parameter) && !ReadOnly)
             return _isFixedParameterEditRepository;
 
+         //in any other case, standard edit
          return _standardParameterEditRepository;
       }
 
diff --git a/tests/PKSim.Tests/Presentation/ExpressionParametersPresenterSpecs.cs b/tests/PKSim.Tests/Presentation/ExpressionParametersPresenterSpecs.cs
index ae01ca71c..bc32612c9 100644
--- a/tests/PKSim.Tests/Presentation/ExpressionParametersPresenterSpecs.cs
+++ b/tests/PKSim.Tests/Presentation/ExpressionParametersPresenterSpecs.cs
@@ -24,22 +24,21 @@ public abstract class concern_for_ExpressionParametersPresenter : ContextSpecifi
 
       protected override void Context()
       {
-         _view= A.Fake<IExpressionParametersView<ExpressionParameterDTO>>();
-         _editParameterTask= A.Fake<IEditParameterPresenterTask>();  
-         sut = new ExpressionParametersPresenter(_view,_editParameterTask);
+         _view = A.Fake<IExpressionParametersView<ExpressionParameterDTO>>();
+         _editParameterTask = A.Fake<IEditParameterPresenterTask>();
+         sut = new ExpressionParametersPresenter(_view, _editParameterTask);
 
 
          _initialConcentration = createParameter(CoreConstants.Parameters.INITIAL_CONCENTRATION);
          _relativeExpression = createParameter(CoreConstants.Parameters.REL_EXP);
          _relativeExpression2 = createParameter(CoreConstants.Parameters.REL_EXP);
          _fraction_exp_bc = createParameter(CoreConstants.Parameters.FRACTION_EXPRESSED_BLOOD_CELLS);
-     
       }
 
       private ExpressionParameterDTO createParameter(string parameterName)
       {
          return new ExpressionParameterDTO
-            { Parameter = new ParameterDTO(DomainHelperForSpecs.ConstantParameterWithValue(1).WithName(parameterName)) };
+            {Parameter = new ParameterDTO(DomainHelperForSpecs.ConstantParameterWithValue(1).WithName(parameterName))};
       }
    }
 
@@ -52,7 +51,7 @@ protected override void Context()
          _relativeExpression.Parameter.Parameter.Value = 5;
          _relativeExpression2.Parameter.Parameter.Value = 10;
 
-         sut.Edit(new []{_fraction_exp_bc, _initialConcentration, _relativeExpression, _relativeExpression2, });
+         sut.Edit(new[] {_fraction_exp_bc, _initialConcentration, _relativeExpression, _relativeExpression2,});
 
          //Make sure that we in fact update the value of the parameter as the command will not be executed
          A.CallTo(() => _editParameterTask.SetParameterValue(sut, _relativeExpression.Parameter, 20))
@@ -72,7 +71,6 @@ public void should_also_calculate_the_normalized_value()
       }
    }
 
-
    public class When_switching_the_visibility_of_initial_concentration_parameters_off : concern_for_ExpressionParametersPresenter
    {
       private List<ExpressionParameterDTO> _allExpressionParameterDTO;
@@ -80,11 +78,10 @@ public class When_switching_the_visibility_of_initial_concentration_parameters_o
       protected override void Context()
       {
          base.Context();
-         sut.Edit(new[] { _fraction_exp_bc, _initialConcentration, _relativeExpression, _relativeExpression2, });
+         sut.Edit(new[] {_fraction_exp_bc, _initialConcentration, _relativeExpression, _relativeExpression2,});
 
          A.CallTo(() => _view.BindTo(A<IEnumerable<ExpressionParameterDTO>>._))
             .Invokes(x => _allExpressionParameterDTO = x.GetArgument<IEnumerable<ExpressionParameterDTO>>(0).ToList());
-
       }
 
       protected override void Because()
@@ -102,10 +99,11 @@ public void should_hide_concentration_parameters()
    public class When_switching_the_visibility_of_initial_concentration_parameters_on : concern_for_ExpressionParametersPresenter
    {
       private List<ExpressionParameterDTO> _allExpressionParameterDTO;
+
       protected override void Context()
       {
          base.Context();
-         sut.Edit(new[] { _fraction_exp_bc, _initialConcentration, _relativeExpression, _relativeExpression2, });
+         sut.Edit(new[] {_fraction_exp_bc, _initialConcentration, _relativeExpression, _relativeExpression2,});
 
          A.CallTo(() => _view.BindTo(A<IEnumerable<ExpressionParameterDTO>>._))
             .Invokes(x => _allExpressionParameterDTO = x.GetArgument<IEnumerable<ExpressionParameterDTO>>(0).ToList());
@@ -123,4 +121,17 @@ public void should_show_concentration_parameters()
       }
    }
 
+   public class When_disabling_edition_in_the_expression_presenter : concern_for_ExpressionParametersPresenter
+   {
+      protected override void Because()
+      {
+         sut.DisableEdit();
+      }
+
+      [Observation]
+      public void should_set_the_view_as_readonly()
+      {
+         _view.ReadOnly.ShouldBeTrue();
+      }
+   }
 }
\ No newline at end of file