diff --git a/pkgs/development/python-modules/retworkx/cargo-lock.patch b/pkgs/development/python-modules/retworkx/cargo-lock.patch
new file mode 100644
index 0000000000000..50b24736e1a1d
--- /dev/null
+++ b/pkgs/development/python-modules/retworkx/cargo-lock.patch
@@ -0,0 +1,346 @@
+diff --git a/Cargo.lock b/Cargo.lock
+new file mode 100644
+index 0000000..17d0ae9
+--- /dev/null	2020-03-23 18:25:02.854329620 -0400
++++ Cargo.lock	2020-04-10 13:37:23.556103749 -0400
+@@ -0,0 +1,340 @@
++# This file is automatically @generated by Cargo.
++# It is not intended for manual editing.
++[[package]]
++name = "aho-corasick"
++version = "0.7.10"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "memchr 2.3.3 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "autocfg"
++version = "1.0.0"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++
++[[package]]
++name = "ctor"
++version = "0.1.13"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "quote 1.0.3 (registry+https://github.com/rust-lang/crates.io-index)",
++ "syn 1.0.17 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "fixedbitset"
++version = "0.2.0"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++
++[[package]]
++name = "ghost"
++version = "0.1.1"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "proc-macro2 1.0.10 (registry+https://github.com/rust-lang/crates.io-index)",
++ "quote 1.0.3 (registry+https://github.com/rust-lang/crates.io-index)",
++ "syn 1.0.17 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "indexmap"
++version = "1.3.2"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "autocfg 1.0.0 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "indoc"
++version = "0.3.5"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "indoc-impl 0.3.5 (registry+https://github.com/rust-lang/crates.io-index)",
++ "proc-macro-hack 0.5.15 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "indoc-impl"
++version = "0.3.5"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "proc-macro-hack 0.5.15 (registry+https://github.com/rust-lang/crates.io-index)",
++ "proc-macro2 1.0.10 (registry+https://github.com/rust-lang/crates.io-index)",
++ "quote 1.0.3 (registry+https://github.com/rust-lang/crates.io-index)",
++ "syn 1.0.17 (registry+https://github.com/rust-lang/crates.io-index)",
++ "unindent 0.1.5 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "inventory"
++version = "0.1.6"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "ctor 0.1.13 (registry+https://github.com/rust-lang/crates.io-index)",
++ "ghost 0.1.1 (registry+https://github.com/rust-lang/crates.io-index)",
++ "inventory-impl 0.1.6 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "inventory-impl"
++version = "0.1.6"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "proc-macro2 1.0.10 (registry+https://github.com/rust-lang/crates.io-index)",
++ "quote 1.0.3 (registry+https://github.com/rust-lang/crates.io-index)",
++ "syn 1.0.17 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "itoa"
++version = "0.4.5"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++
++[[package]]
++name = "lazy_static"
++version = "1.4.0"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++
++[[package]]
++name = "libc"
++version = "0.2.68"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++
++[[package]]
++name = "memchr"
++version = "2.3.3"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++
++[[package]]
++name = "num-traits"
++version = "0.2.11"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "autocfg 1.0.0 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "paste"
++version = "0.1.10"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "paste-impl 0.1.10 (registry+https://github.com/rust-lang/crates.io-index)",
++ "proc-macro-hack 0.5.15 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "paste-impl"
++version = "0.1.10"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "proc-macro-hack 0.5.15 (registry+https://github.com/rust-lang/crates.io-index)",
++ "proc-macro2 1.0.10 (registry+https://github.com/rust-lang/crates.io-index)",
++ "quote 1.0.3 (registry+https://github.com/rust-lang/crates.io-index)",
++ "syn 1.0.17 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "petgraph"
++version = "0.5.0"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "fixedbitset 0.2.0 (registry+https://github.com/rust-lang/crates.io-index)",
++ "indexmap 1.3.2 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "proc-macro-hack"
++version = "0.5.15"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++
++[[package]]
++name = "proc-macro2"
++version = "1.0.10"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "unicode-xid 0.2.0 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "pyo3"
++version = "0.8.5"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "indoc 0.3.5 (registry+https://github.com/rust-lang/crates.io-index)",
++ "inventory 0.1.6 (registry+https://github.com/rust-lang/crates.io-index)",
++ "lazy_static 1.4.0 (registry+https://github.com/rust-lang/crates.io-index)",
++ "libc 0.2.68 (registry+https://github.com/rust-lang/crates.io-index)",
++ "num-traits 0.2.11 (registry+https://github.com/rust-lang/crates.io-index)",
++ "paste 0.1.10 (registry+https://github.com/rust-lang/crates.io-index)",
++ "pyo3cls 0.8.5 (registry+https://github.com/rust-lang/crates.io-index)",
++ "regex 1.3.6 (registry+https://github.com/rust-lang/crates.io-index)",
++ "serde 1.0.106 (registry+https://github.com/rust-lang/crates.io-index)",
++ "serde_json 1.0.51 (registry+https://github.com/rust-lang/crates.io-index)",
++ "spin 0.5.2 (registry+https://github.com/rust-lang/crates.io-index)",
++ "unindent 0.1.5 (registry+https://github.com/rust-lang/crates.io-index)",
++ "version_check 0.9.1 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "pyo3-derive-backend"
++version = "0.8.5"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "proc-macro2 1.0.10 (registry+https://github.com/rust-lang/crates.io-index)",
++ "quote 1.0.3 (registry+https://github.com/rust-lang/crates.io-index)",
++ "syn 1.0.17 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "pyo3cls"
++version = "0.8.5"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "proc-macro2 1.0.10 (registry+https://github.com/rust-lang/crates.io-index)",
++ "pyo3-derive-backend 0.8.5 (registry+https://github.com/rust-lang/crates.io-index)",
++ "quote 1.0.3 (registry+https://github.com/rust-lang/crates.io-index)",
++ "syn 1.0.17 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "quote"
++version = "1.0.3"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "proc-macro2 1.0.10 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "regex"
++version = "1.3.6"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "aho-corasick 0.7.10 (registry+https://github.com/rust-lang/crates.io-index)",
++ "memchr 2.3.3 (registry+https://github.com/rust-lang/crates.io-index)",
++ "regex-syntax 0.6.17 (registry+https://github.com/rust-lang/crates.io-index)",
++ "thread_local 1.0.1 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "regex-syntax"
++version = "0.6.17"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++
++[[package]]
++name = "retworkx"
++version = "0.3.3"
++dependencies = [
++ "fixedbitset 0.2.0 (registry+https://github.com/rust-lang/crates.io-index)",
++ "petgraph 0.5.0 (registry+https://github.com/rust-lang/crates.io-index)",
++ "pyo3 0.8.5 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
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++source = "registry+https://github.com/rust-lang/crates.io-index"
++
++[[package]]
++name = "serde"
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++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "serde_derive 1.0.106 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
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++ "quote 1.0.3 (registry+https://github.com/rust-lang/crates.io-index)",
++ "syn 1.0.17 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "serde_json"
++version = "1.0.51"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "itoa 0.4.5 (registry+https://github.com/rust-lang/crates.io-index)",
++ "ryu 1.0.3 (registry+https://github.com/rust-lang/crates.io-index)",
++ "serde 1.0.106 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "spin"
++version = "0.5.2"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++
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++name = "syn"
++version = "1.0.17"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "proc-macro2 1.0.10 (registry+https://github.com/rust-lang/crates.io-index)",
++ "quote 1.0.3 (registry+https://github.com/rust-lang/crates.io-index)",
++ "unicode-xid 0.2.0 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "thread_local"
++version = "1.0.1"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++dependencies = [
++ "lazy_static 1.4.0 (registry+https://github.com/rust-lang/crates.io-index)",
++]
++
++[[package]]
++name = "unicode-xid"
++version = "0.2.0"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++
++[[package]]
++name = "unindent"
++version = "0.1.5"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++
++[[package]]
++name = "version_check"
++version = "0.9.1"
++source = "registry+https://github.com/rust-lang/crates.io-index"
++
++[metadata]
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++"checksum itoa 0.4.5 (registry+https://github.com/rust-lang/crates.io-index)" = "b8b7a7c0c47db5545ed3fef7468ee7bb5b74691498139e4b3f6a20685dc6dd8e"
++"checksum lazy_static 1.4.0 (registry+https://github.com/rust-lang/crates.io-index)" = "e2abad23fbc42b3700f2f279844dc832adb2b2eb069b2df918f455c4e18cc646"
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++"checksum memchr 2.3.3 (registry+https://github.com/rust-lang/crates.io-index)" = "3728d817d99e5ac407411fa471ff9800a778d88a24685968b36824eaf4bee400"
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diff --git a/pkgs/development/python-modules/retworkx/default.nix b/pkgs/development/python-modules/retworkx/default.nix
new file mode 100644
index 0000000000000..91aee3c5da22a
--- /dev/null
+++ b/pkgs/development/python-modules/retworkx/default.nix
@@ -0,0 +1,71 @@
+{ stdenv
+, lib
+, rustPlatform
+, buildPythonPackage
+# , fetchFromGitHub
+, fetchPypi
+# , setuptools-rust
+  # Check inputs
+, pytestCheckHook
+}:
+
+# let
+#   pn = "retworkx";
+#   v = "0.3.3";
+#   src-raw = fetchFromGitHub {
+#     owner = "Qiskit";
+#     repo = "retworkx";
+#     rev = v;
+#     sha256 = "160w5vkzrl5rzcrdwhjq820i5lmc527m6hg0kxx0k6n2bz9qn26g";
+#   };
+
+#   retworkx-rs = rustPlatform.buildRustPackage {
+#     pname = pn;
+#     version = v;
+
+#     src = src-raw;
+#     cargoPatches = [ ./cargo-lock.patch ];
+#     cargoSha256 = "1hkidvyyw2p75x1xk98fl023sm1fpjihssqsg839bi5m09hj0sd4";
+#   };
+
+# in
+buildPythonPackage rec {
+  pname = "retworkx";
+  version = "0.3.3";
+  format = "wheel";
+
+  # src = src-raw;
+  src = fetchPypi {
+    inherit pname version format;
+    python = "cp37";
+    # abi = "cp37m";
+    platform = "manylinux2010_x86_64";
+    sha256 = "1gbz7sh9i4h41xs9c40lixfdigmvfykkgxgzwsrs8v0smx20dczy";
+  };
+
+  buildInputs = [
+    # retworkx-rs
+  ];
+
+  propagatedBuildInputs = [
+
+  ];
+
+  pythonImportsCheck = [ "retworkx" ];
+
+  # checkInputs = [ pytestCheckHook ];
+  # dontUseSetuptoolsCheck = true;
+
+  checkPhase = ''
+    python -c "import retworkx; retworkx.PyDAG()"
+    echo "Retworkx basic usage check succeeded"
+  '';
+
+  meta = with lib; {
+    description = "A python graph library implemented in Rust.";
+    homepage = "https://retworkx.readthedocs.io/en/latest/index.html";
+    downloadPage = "https://github.com/Qiskit/retworkx/releases";
+    license = licenses.asl20;
+    maintainers = with maintainers; [ drewrisinger ];
+  };
+}
diff --git a/pkgs/development/python-modules/setuptools-rust/default.nix b/pkgs/development/python-modules/setuptools-rust/default.nix
new file mode 100644
index 0000000000000..1f05eba4838bc
--- /dev/null
+++ b/pkgs/development/python-modules/setuptools-rust/default.nix
@@ -0,0 +1,58 @@
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, pkgs
+  # Python Packages
+, semantic-version
+, toml
+  # Check inputs
+, pytest
+, python
+}:
+
+buildPythonPackage rec {
+  pname = "setuptools-rust";
+  version = "0.10.6";
+
+  src = fetchFromGitHub {
+    owner = "PyO3";
+    repo = "setuptools-rust";
+    rev = "v${version}";
+    sha256 = "19q0b17n604ngcv8lq5imb91i37frr1gppi8rrg6s4f5aajsm5fm";
+  };
+
+  # buildInputs = [
+  #   pkgs.cargo
+  #   pkgs.rustc
+  # ];
+
+  propagatedBuildInputs = [
+    # pkgs.cargo
+    # pkgs.rustc  # permanent linking doesn't work as I hoped...
+    semantic-version
+    toml
+  ];
+
+  doCheck = true;
+  checkInputs = [ python pytest pkgs.rustc pkgs.cargo ];
+  dontUseSetuptoolsCheck = true;
+
+  # From .travis.yml:
+  checkPhase = ''
+    # pushd example_tomlgen
+    # DISTUTILS_DEBUG=1 python setup.py tomlgen_rust -w build
+    # popd
+
+    pushd html-py-ever
+    cp ../nix_run_setup .
+    DISTUTILS_DEBUG=1 python nix_run_setup install --prefix="$out"
+    pytest
+  '';
+
+  meta = with lib; {
+    description = "Setuptools plugin for Rust support.";
+    homepage = "";
+    license = licenses.mit;
+    maintainers = with maintainers; [ drewrisinger ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 74c35edad8f67..0d63c95089c2e 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -3376,6 +3376,8 @@ in {
 
   setuptools-git = callPackage ../development/python-modules/setuptools-git { };
 
+  setuptools-rust = callPackage ../development/python-modules/setuptools-rust { };
+
   sievelib = callPackage ../development/python-modules/sievelib { };
 
   watchdog = callPackage ../development/python-modules/watchdog { };
@@ -5495,6 +5497,8 @@ in {
 
   readchar = callPackage ../development/python-modules/readchar { };
 
+  retworkx = callPackage ../development/python-modules/retworkx { };
+
   rivet = disabledIf isPy3k (toPythonModule (pkgs.rivet.override {
     python2 = python;
   }));