diff --git a/pkgs/development/python-modules/picobox/default.nix b/pkgs/development/python-modules/picobox/default.nix
new file mode 100644
index 0000000000000..6094b65efaac3
--- /dev/null
+++ b/pkgs/development/python-modules/picobox/default.nix
@@ -0,0 +1,59 @@
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, fetchpatch
+, flask
+, isPy27
+, pytestCheckHook
+, pythonAtLeast
+, setuptools-scm
+}:
+
+buildPythonPackage rec {
+  pname = "picobox";
+  version = "2.2.0";
+
+  disabled = isPy27;
+
+  src = fetchFromGitHub {
+    owner = "ikalnytskyi";
+    repo = pname;
+    rev = "refs/tags/${version}";
+    hash = "sha256-B2A8GMhBFU/mb/JiiqtP+HvpPj5FYwaYO3gQN2QI6z0=";
+  };
+
+  patches = [
+    (fetchpatch {
+      # already in master, but no new release yet.
+      # https://github.com/ikalnytskyi/picobox/issues/55
+      url = "https://github.com/ikalnytskyi/picobox/commit/1fcc4a0c26a7cd50ee3ef6694139177b5dfb2be0.patch";
+      hash = "sha256-/NIEzTFlZ5wG7jHT/YdySYoxT/UhSk29Up9/VqjG/jg=";
+      includes = [
+        "tests/test_box.py"
+        "tests/test_stack.py"
+      ];
+    })
+  ];
+
+  SETUPTOOLS_SCM_PRETEND_VERSION = version;
+
+  nativeBuildInputs = [
+    setuptools-scm
+  ];
+
+  checkInputs = [
+    flask
+    pytestCheckHook
+  ];
+
+  pythonImportsCheck = [
+    "picobox"
+  ];
+
+  meta = with lib; {
+    description = "Opinionated dependency injection framework";
+    homepage = "https://github.com/ikalnytskyi/picobox";
+    license = licenses.mit;
+    maintainers = with maintainers; [ flokli ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 025ae352ec48d..eb3b661d63505 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -6736,6 +6736,8 @@ in {
 
   pickleshare = callPackage ../development/python-modules/pickleshare { };
 
+  picobox = callPackage ../development/python-modules/picobox { };
+
   picos = callPackage ../development/python-modules/picos { };
 
   pid = callPackage ../development/python-modules/pid { };