diff --git a/components/select/select.component.ts b/components/select/select.component.ts
index af84d1def47..eaf1732a557 100644
--- a/components/select/select.component.ts
+++ b/components/select/select.component.ts
@@ -37,7 +37,7 @@ import { startWith, switchMap, takeUntil } from 'rxjs/operators';
 import { slideMotion } from 'ng-zorro-antd/core/animation';
 import { NzConfigKey, NzConfigService, WithConfig } from 'ng-zorro-antd/core/config';
 import { NzNoAnimationDirective } from 'ng-zorro-antd/core/no-animation';
-import { reqAnimFrame } from 'ng-zorro-antd/core/polyfill';
+import { cancelRequestAnimationFrame, reqAnimFrame } from 'ng-zorro-antd/core/polyfill';
 import { NzDestroyService } from 'ng-zorro-antd/core/services';
 import { BooleanInput, NzSafeAny, OnChangeType, OnTouchedType } from 'ng-zorro-antd/core/types';
 import { InputBoolean, isNotNil } from 'ng-zorro-antd/core/util';
@@ -242,6 +242,7 @@ export class NzSelectComponent implements ControlValueAccessor, OnInit, AfterCon
   private isReactiveDriven = false;
   private value: NzSafeAny | NzSafeAny[];
   private _nzShowArrow: boolean | undefined;
+  private requestId: number = -1;
   onChange: OnChangeType = () => {};
   onTouched: OnTouchedType = () => {};
   dropDownPosition: 'top' | 'center' | 'bottom' = 'bottom';
@@ -491,9 +492,18 @@ export class NzSelectComponent implements ControlValueAccessor, OnInit, AfterCon
 
   updateCdkConnectedOverlayStatus(): void {
     if (this.platform.isBrowser && this.originElement.nativeElement) {
-      reqAnimFrame(() => {
+      const triggerWidth = this.triggerWidth;
+      cancelRequestAnimationFrame(this.requestId);
+      this.requestId = reqAnimFrame(() => {
+        // Blink triggers style and layout pipelines anytime the `getBoundingClientRect()` is called, which may cause a
+        // frame drop. That's why it's scheduled through the `requestAnimationFrame` to unload the composite thread.
         this.triggerWidth = this.originElement.nativeElement.getBoundingClientRect().width;
-        this.cdr.markForCheck();
+        if (triggerWidth !== this.triggerWidth) {
+          // The `requestAnimationFrame` will trigger change detection, but we're inside an `OnPush` component which won't have
+          // the `ChecksEnabled` state. Calling `markForCheck()` will allow Angular to run the change detection from the root component
+          // down to the `nz-select`. But we'll trigger only local change detection if the `triggerWidth` has been changed.
+          this.cdr.detectChanges();
+        }
       });
     }
   }
@@ -672,6 +682,7 @@ export class NzSelectComponent implements ControlValueAccessor, OnInit, AfterCon
     }
   }
   ngOnDestroy(): void {
+    cancelRequestAnimationFrame(this.requestId);
     this.focusMonitor.stopMonitoring(this.elementRef);
   }
 }
diff --git a/components/select/select.spec.ts b/components/select/select.spec.ts
index c667772b4c8..6ee39cd62d0 100644
--- a/components/select/select.spec.ts
+++ b/components/select/select.spec.ts
@@ -1,7 +1,7 @@
 import { BACKSPACE, DOWN_ARROW, ENTER, ESCAPE, SPACE, TAB, UP_ARROW } from '@angular/cdk/keycodes';
 import { OverlayContainer } from '@angular/cdk/overlay';
 import { Component, TemplateRef, ViewChild } from '@angular/core';
-import { ComponentFixture, fakeAsync, flush, inject } from '@angular/core/testing';
+import { ComponentFixture, fakeAsync, flush, inject, tick } from '@angular/core/testing';
 import { FormsModule } from '@angular/forms';
 import { By } from '@angular/platform-browser';
 
@@ -1180,6 +1180,50 @@ describe('select', () => {
       expect(listOfItem[2].textContent).toBe('and 2 more selected');
     }));
   });
+  describe('change detection', () => {
+    let testBed: ComponentBed<TestSelectTemplateDefaultComponent>;
+    let component: TestSelectTemplateDefaultComponent;
+    let fixture: ComponentFixture<TestSelectTemplateDefaultComponent>;
+    let selectComponent: NzSelectComponent;
+    let overlayContainerElement: HTMLElement;
+
+    beforeEach(() => {
+      testBed = createComponentBed(TestSelectTemplateDefaultComponent, {
+        imports: [NzSelectModule, NzIconTestModule, FormsModule]
+      });
+      component = testBed.component;
+      fixture = testBed.fixture;
+      selectComponent = testBed.debugElement.query(By.directive(NzSelectComponent)).componentInstance;
+    });
+
+    beforeEach(inject([OverlayContainer], (oc: OverlayContainer) => {
+      overlayContainerElement = oc.getContainerElement();
+    }));
+
+    it('should not run change detection if the `triggerWidth` have not been changed', fakeAsync(() => {
+      const detectChangesSpy = spyOn(selectComponent['cdr'], 'detectChanges').and.callThrough();
+      const requestAnimationFrameSpy = spyOn(window, 'requestAnimationFrame').and.callThrough();
+
+      component.nzOpen = true;
+      fixture.detectChanges();
+      // The `requestAnimationFrame` is simulated as `setTimeout(..., 16)` inside the `fakeAsync`.
+      tick(16);
+
+      dispatchKeyboardEvent(overlayContainerElement, 'keydown', ESCAPE, overlayContainerElement);
+      fixture.detectChanges();
+      flush();
+
+      expect(component.nzOpen).toEqual(false);
+
+      component.nzOpen = true;
+      fixture.detectChanges();
+      tick(16);
+
+      // Ensure that the `detectChanges()` have been called only once since the `triggerWidth` haven't been changed.
+      expect(detectChangesSpy).toHaveBeenCalledTimes(1);
+      expect(requestAnimationFrameSpy).toHaveBeenCalledTimes(2);
+    }));
+  });
 });
 
 @Component({