diff --git a/Cargo.toml b/Cargo.toml
index 7956781..adbaba0 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -27,7 +27,7 @@ exclude = ["release-plz.toml", ".github", "python"]
 [dependencies]
 derive_more = "0.99.17"
 general-sam = { version = "1.0.0", features = ["trie"] }
-pyo3 = { version = "0.21.2", optional = true }
+pyo3 = { version = "0.22.1", optional = true }
 smallvec = "1.13.2"
 thiserror = "1.0.60"
 
diff --git a/python/Cargo.toml b/python/Cargo.toml
index 171f443..4e401a3 100644
--- a/python/Cargo.toml
+++ b/python/Cargo.toml
@@ -16,4 +16,4 @@ crate-type = ["cdylib"]
 
 [dependencies]
 mtc-token-healing = { version = "0.1.2", path = "..", features = ["pyo3"] }
-pyo3 = { version = "0.21.2", features = ["extension-module", "generate-import-lib", "abi3-py39"] }
+pyo3 = { version = "0.22.1", features = ["extension-module", "generate-import-lib", "abi3-py39"] }