diff --git a/app/scripts/lib/createRPCMethodTrackingMiddleware.js b/app/scripts/lib/createRPCMethodTrackingMiddleware.js
index 9073a26c3ae5..e1376ae1e785 100644
--- a/app/scripts/lib/createRPCMethodTrackingMiddleware.js
+++ b/app/scripts/lib/createRPCMethodTrackingMiddleware.js
@@ -1,3 +1,4 @@
+import { errorCodes } from 'eth-rpc-errors';
 import { MESSAGE_TYPE, ORIGIN_METAMASK } from '../../../shared/constants/app';
 import { SECOND } from '../../../shared/constants/time';
 import { detectSIWE } from '../../../shared/modules/siwe';
@@ -46,6 +47,7 @@ const RATE_LIMIT_MAP = {
 const EVENT_NAME_MAP = {
   [MESSAGE_TYPE.ETH_SIGN]: {
     APPROVED: EVENT_NAMES.SIGNATURE_APPROVED,
+    FAILED: EVENT_NAMES.SIGNATURE_FAILED,
     REJECTED: EVENT_NAMES.SIGNATURE_REJECTED,
     REQUESTED: EVENT_NAMES.SIGNATURE_REQUESTED,
   },
@@ -195,13 +197,25 @@ export default function createRPCMethodTrackingMiddleware({
         return callback();
       }
 
-      // An error code of 4001 means the user rejected the request, which we
-      // can use here to determine which event to track.
-      const event =
-        res.error?.code === 4001 ? eventType.REJECTED : eventType.APPROVED;
-
       const properties = {};
 
+      // The rpc error methodNotFound implies that 'eth_sign' is disabled in Advanced Settings
+      const isDisabledEthSignAdvancedSetting =
+        method === MESSAGE_TYPE.ETH_SIGN &&
+        res.error?.code === errorCodes.rpc.methodNotFound;
+
+      const isDisabledRPCMethod = isDisabledEthSignAdvancedSetting;
+
+      let event;
+      if (isDisabledRPCMethod) {
+        event = eventType.FAILED;
+        properties.error = res.error;
+      } else if (res.error?.code === 4001) {
+        event = eventType.REJECTED;
+      } else {
+        event = eventType.APPROVED;
+      }
+
       if (eventType.REQUESTED === EVENT_NAMES.SIGNATURE_REQUESTED) {
         properties.signature_type = method;
       } else {
@@ -226,6 +240,7 @@ export default function createRPCMethodTrackingMiddleware({
         },
         properties,
       });
+
       return callback();
     });
   };
diff --git a/app/scripts/lib/createRPCMethodTrackingMiddleware.test.js b/app/scripts/lib/createRPCMethodTrackingMiddleware.test.js
index ffa953fa0f75..9a9f72157703 100644
--- a/app/scripts/lib/createRPCMethodTrackingMiddleware.test.js
+++ b/app/scripts/lib/createRPCMethodTrackingMiddleware.test.js
@@ -1,3 +1,4 @@
+import { errorCodes } from 'eth-rpc-errors';
 import { MESSAGE_TYPE } from '../../../shared/constants/app';
 import { EVENT_NAMES } from '../../../shared/constants/metametrics';
 import { SECOND } from '../../../shared/constants/time';
@@ -213,5 +214,34 @@ describe('createRPCMethodTrackingMiddleware', () => {
       expect(trackEvent.mock.calls[0][0].properties.method).toBe('eth_chainId');
       expect(trackEvent.mock.calls[1][0].properties.method).toBe('eth_chainId');
     });
+
+    describe(`when '${MESSAGE_TYPE.ETH_SIGN}' is disabled in advanced settings`, () => {
+      it(`should track ${EVENT_NAMES.SIGNATURE_FAILED} and include error property`, async () => {
+        const mockError = { code: errorCodes.rpc.methodNotFound };
+        const req = {
+          method: MESSAGE_TYPE.ETH_SIGN,
+          origin: 'some.dapp',
+        };
+        const res = {
+          error: mockError,
+        };
+        const { next, executeMiddlewareStack } = getNext();
+
+        handler(req, res, next);
+        await executeMiddlewareStack();
+
+        expect(trackEvent).toHaveBeenCalledTimes(2);
+
+        expect(trackEvent.mock.calls[1][0]).toMatchObject({
+          category: 'inpage_provider',
+          event: EVENT_NAMES.SIGNATURE_FAILED,
+          properties: {
+            signature_type: MESSAGE_TYPE.ETH_SIGN,
+            error: mockError,
+          },
+          referrer: { url: 'some.dapp' },
+        });
+      });
+    });
   });
 });
diff --git a/shared/constants/metametrics.js b/shared/constants/metametrics.js
index 62423b94fc35..b6facb12ba9d 100644
--- a/shared/constants/metametrics.js
+++ b/shared/constants/metametrics.js
@@ -342,6 +342,7 @@ export const EVENT_NAMES = {
   PUBLIC_ADDRESS_COPIED: 'Public Address Copied',
   PROVIDER_METHOD_CALLED: 'Provider Method Called',
   SIGNATURE_APPROVED: 'Signature Approved',
+  SIGNATURE_FAILED: 'Signature Failed',
   SIGNATURE_REJECTED: 'Signature Rejected',
   SIGNATURE_REQUESTED: 'Signature Requested',
   TOKEN_IMPORT_BUTTON_CLICKED: 'Import Token Button Clicked',