diff --git a/buildroot/share/PlatformIO/variants/MARLIN_F103Zx/PinNamesVar.h b/buildroot/share/PlatformIO/variants/MARLIN_F103Zx/PinNamesVar.h
index d9076b4dfb59..b0259ab3355a 100644
--- a/buildroot/share/PlatformIO/variants/MARLIN_F103Zx/PinNamesVar.h
+++ b/buildroot/share/PlatformIO/variants/MARLIN_F103Zx/PinNamesVar.h
@@ -1,5 +1,6 @@
 /* SYS_WKUP */
-#ifdef PWR_WAKEUP_PIN1
+#if defined(PWR_WAKEUP_PIN1) && defined(HAL_PWR_MODULE_ENABLED) && !defined(HAL_PWR_MODULE_ONLY)
+  #error "PA0 is used by thermal sensor. Disable low power wake with -DHAL_PWR_MODULE_ONLY."
   SYS_WKUP1 = PA_0,
 #endif
 #ifdef PWR_WAKEUP_PIN2
diff --git a/buildroot/share/PlatformIO/variants/MARLIN_F103Zx/hal_conf_custom.h b/buildroot/share/PlatformIO/variants/MARLIN_F103Zx/hal_conf_custom.h
index 4e55fe1240f3..4da94a789358 100644
--- a/buildroot/share/PlatformIO/variants/MARLIN_F103Zx/hal_conf_custom.h
+++ b/buildroot/share/PlatformIO/variants/MARLIN_F103Zx/hal_conf_custom.h
@@ -72,6 +72,8 @@ extern "C" {
 //#define HAL_WWDG_MODULE_ENABLED
 //#define HAL_MMC_MODULE_ENABLED
 
+#define HAL_PWR_MODULE_ONLY
+
 /* ########################## Oscillator Values adaptation ####################*/
 /**
   * @brief Adjust the value of External High Speed oscillator (HSE) used in your application.