diff --git a/README.md b/README.md
index 854492a98..80e1ea1fd 100644
--- a/README.md
+++ b/README.md
@@ -33,7 +33,7 @@ More information and documentation can be found at https://tedana.readthedocs.io
 You'll need to set up a working development environment to use `tedana`.
 To set up a local environment, you will need Python >=3.5 and the following packages will need to be installed:
 
-* [numpy](http://www.numpy.org/)
+* [numpy>=1.14](http://www.numpy.org/)
 * [scipy](https://www.scipy.org/)
 * [scikit-learn](http://scikit-learn.org/stable/)
 * [nilearn](https://nilearn.github.io/)
diff --git a/setup.py b/setup.py
index 602cefcf1..d5a4b82ef 100644
--- a/setup.py
+++ b/setup.py
@@ -25,6 +25,7 @@ def main():
         REQUIRES,
         TESTS_REQUIRES,
         EXTRA_REQUIRES,
+        PYTHON_REQUIRES
     )
 
     pkg_data = {
@@ -60,6 +61,7 @@ def main():
         classifiers=CLASSIFIERS,
         download_url=DOWNLOAD_URL,
         # Dependencies handling
+        python_requires=PYTHON_REQUIRES,
         install_requires=REQUIRES,
         tests_require=TESTS_REQUIRES,
         extras_require=EXTRA_REQUIRES,
diff --git a/tedana/info.py b/tedana/info.py
index 6a8f6dae9..79c825f53 100644
--- a/tedana/info.py
+++ b/tedana/info.py
@@ -28,7 +28,7 @@
         name=__packagename__, ver=__version__))
 
 REQUIRES = [
-    'numpy',
+    'numpy >=1.14',
     'scikit-learn',
     'nilearn',
     'nibabel>=2.1.0',
@@ -59,6 +59,10 @@
 EXTRA_REQUIRES['all'] = list(set([
     v for deps in EXTRA_REQUIRES.values() for v in deps]))
 
+# Supported Python versions using PEP 440 version specifiers
+# Should match the same set of Python versions as classifiers
+PYTHON_REQUIRES = ">=3.5"
+
 # Package classifiers
 CLASSIFIERS = [
     'Development Status :: 4 - Beta',