From 0a5a7bec2e32d9ca83ecf80fe5f6fe03613f0c6c Mon Sep 17 00:00:00 2001 From: Fabian Engelniederhammer Date: Tue, 2 Apr 2024 10:16:47 +0200 Subject: [PATCH] feat: return structured mutation and insertion responses #718 --- .github/workflows/lapis2.yml | 1 + .../QueryGenerator/QueryTypeSelectionState.ts | 7 + ...ample_nucleotide_mutation_response_200.png | Bin 68260 -> 71730 bytes .../example_nucleotide_mutation_schema.png | Bin 52460 -> 38726 bytes .../genspectrum/lapis/model/SiloQueryModel.kt | 49 ++++-- .../genspectrum/lapis/openApi/OpenApiDocs.kt | 140 +++++++++++++--- .../lapis/response/LapisResponse.kt | 151 ++++++++++------- .../lapis/response/SiloResponse.kt | 6 +- .../lapis/controller/LapisControllerTest.kt | 62 ++++++- .../genspectrum/lapis/controller/MockData.kt | 90 ++++++---- .../lapis/model/SiloQueryModelTest.kt | 109 +++++++----- .../genspectrum/lapis/silo/SiloClientTest.kt | 155 ++++++++++++------ .../test/aminoAcidInsertions.spec.ts | 36 ++-- .../test/aminoAcidMutations.spec.ts | 32 ++-- .../test/nucleotideInsertions.spec.ts | 31 ++-- .../test/nucleotideMutations.spec.ts | 28 +++- 16 files changed, 624 insertions(+), 273 deletions(-) diff --git a/.github/workflows/lapis2.yml b/.github/workflows/lapis2.yml index 32ccaae0..3c589861 100644 --- a/.github/workflows/lapis2.yml +++ b/.github/workflows/lapis2.yml @@ -137,6 +137,7 @@ jobs: - name: Start SILO and LAPIS and Run Tests run: | + docker compose -f lapis2/docker-compose.yml pull docker compose -f lapis2/docker-compose.yml up -d --wait cd siloLapisTests && npm run test env: diff --git a/lapis2-docs/src/components/QueryGenerator/QueryTypeSelectionState.ts b/lapis2-docs/src/components/QueryGenerator/QueryTypeSelectionState.ts index c878a112..ac365370 100644 --- a/lapis2-docs/src/components/QueryGenerator/QueryTypeSelectionState.ts +++ b/lapis2-docs/src/components/QueryGenerator/QueryTypeSelectionState.ts @@ -101,11 +101,18 @@ function getFieldsThatAreAlwaysPresent(selection: Selection): ResultField[] { { name: 'mutation', type: 'string', nullable: false }, { name: 'proportion', type: 'string', nullable: false }, { name: 'count', type: 'integer', nullable: false }, + { name: 'sequenceName', type: 'string', nullable: true }, + { name: 'mutationFrom', type: 'string', nullable: false }, + { name: 'mutationTo', type: 'string', nullable: false }, + { name: 'position', type: 'integer', nullable: false }, ]; case 'insertions': return [ { name: 'insertion', type: 'string', nullable: false }, { name: 'count', type: 'integer', nullable: false }, + { name: 'insertedSymbols', type: 'string', nullable: false }, + { name: 'sequenceName', type: 'string', nullable: false }, + { name: 'position', type: 'integer', nullable: false }, ]; case 'details': case 'nucleotideSequences': diff --git a/lapis2-docs/src/images/concepts/example_nucleotide_mutation_response_200.png b/lapis2-docs/src/images/concepts/example_nucleotide_mutation_response_200.png index 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a/lapis2/src/main/kotlin/org/genspectrum/lapis/model/SiloQueryModel.kt b/lapis2/src/main/kotlin/org/genspectrum/lapis/model/SiloQueryModel.kt index 10438e26..5991dbcc 100644 --- a/lapis2/src/main/kotlin/org/genspectrum/lapis/model/SiloQueryModel.kt +++ b/lapis2/src/main/kotlin/org/genspectrum/lapis/model/SiloQueryModel.kt @@ -50,13 +50,23 @@ class SiloQueryModel( ), ) return data.map { - val sequenceName = - if (referenceGenomeSchema.isSingleSegmented()) it.mutation else "${it.sequenceName}:${it.mutation}" + val mutation = if (referenceGenomeSchema.isSingleSegmented()) { + it.mutation + } else { + "${it.sequenceName}:${it.mutation}" + } NucleotideMutationResponse( - sequenceName, - it.count, - it.proportion, + mutation = mutation, + count = it.count, + proportion = it.proportion, + sequenceName = when (referenceGenomeSchema.isSingleSegmented()) { + true -> null + false -> it.sequenceName + }, + mutationFrom = it.mutationFrom, + mutationTo = it.mutationTo, + position = it.position, ) } } @@ -77,9 +87,13 @@ class SiloQueryModel( ) return data.map { AminoAcidMutationResponse( - "${it.sequenceName}:${it.mutation}", - it.count, - it.proportion, + mutation = "${it.sequenceName}:${it.mutation}", + count = it.count, + proportion = it.proportion, + sequenceName = it.sequenceName, + mutationFrom = it.mutationFrom, + mutationTo = it.mutationTo, + position = it.position, ) } } @@ -110,11 +124,15 @@ class SiloQueryModel( ) return data.map { - val sequenceName = if (referenceGenomeSchema.isSingleSegmented()) "" else "${it.sequenceName}:" - NucleotideInsertionResponse( - "ins_${sequenceName}${it.position}:${it.insertions}", - it.count, + insertion = it.insertion, + count = it.count, + insertedSymbols = it.insertedSymbols, + position = it.position, + sequenceName = when (referenceGenomeSchema.isSingleSegmented()) { + true -> null + false -> it.sequenceName + }, ) } } @@ -133,8 +151,11 @@ class SiloQueryModel( return data.map { AminoAcidInsertionResponse( - "ins_${it.sequenceName}:${it.position}:${it.insertions}", - it.count, + insertion = it.insertion, + count = it.count, + insertedSymbols = it.insertedSymbols, + position = it.position, + sequenceName = it.sequenceName, ) } } diff --git a/lapis2/src/main/kotlin/org/genspectrum/lapis/openApi/OpenApiDocs.kt b/lapis2/src/main/kotlin/org/genspectrum/lapis/openApi/OpenApiDocs.kt index 413098e0..5e1fa1d3 100644 --- a/lapis2/src/main/kotlin/org/genspectrum/lapis/openApi/OpenApiDocs.kt +++ b/lapis2/src/main/kotlin/org/genspectrum/lapis/openApi/OpenApiDocs.kt @@ -5,6 +5,7 @@ import io.swagger.v3.oas.models.OpenAPI import io.swagger.v3.oas.models.media.ArraySchema import io.swagger.v3.oas.models.media.BooleanSchema import io.swagger.v3.oas.models.media.IntegerSchema +import io.swagger.v3.oas.models.media.NumberSchema import io.swagger.v3.oas.models.media.Schema import io.swagger.v3.oas.models.media.StringSchema import org.genspectrum.lapis.config.DatabaseConfig @@ -163,7 +164,11 @@ fun buildOpenApiSchema( .description( "The response contains the metadata of every sequence matching the sequence filters.", ) - .properties(nucleotideMutationProportionSchema()), + .properties(nucleotideMutationProportionSchema()) + .required( + nucleotideMutationProportionSchema().keys + .filterNot { referenceGenomeSchema.isSingleSegmented() && it == "sequenceName" }, + ), ), ) .addSchemas(NUCLEOTIDE_MUTATIONS_SCHEMA, nucleotideMutations()) @@ -175,7 +180,8 @@ fun buildOpenApiSchema( .description( "The response contains the metadata of every sequence matching the sequence filters.", ) - .properties(aminoAcidMutationProportionSchema()), + .properties(aminoAcidMutationProportionSchema()) + .required(aminoAcidMutationProportionSchema().keys.toList()), ), ) .addSchemas( @@ -184,7 +190,11 @@ fun buildOpenApiSchema( Schema() .type("object") .description("Nucleotide Insertion data.") - .properties(nucleotideInsertionSchema()), + .properties(nucleotideInsertionSchema()) + .required( + nucleotideInsertionSchema().keys + .filterNot { referenceGenomeSchema.isSingleSegmented() && it == "sequenceName" }, + ), ), ) .addSchemas( @@ -193,7 +203,8 @@ fun buildOpenApiSchema( Schema() .type("object") .description("Amino Acid Insertion data.") - .properties(aminoAcidInsertionSchema()), + .properties(aminoAcidInsertionSchema()) + .required(aminoAcidInsertionSchema().keys.toList()), ), ) .addSchemas(FIELDS_TO_AGGREGATE_BY_SCHEMA, fieldsArray(databaseConfig.schema.metadata)) @@ -372,42 +383,112 @@ private fun getAggregatedResponseProperties(filterProperties: Map = StringSchema().description(ACCESS_KEY_DESCRIPTION) private fun nucleotideMutationProportionSchema() = mapOf( - "mutation" to Schema().type("string").example("T123C").description("The mutation that was found."), - "proportion" to Schema().type("number").description("The proportion of sequences having the mutation."), - "count" to Schema().type("integer") - .description("The number of sequences matching having the mutation."), + "mutation" to StringSchema() + .example("sequence1:G29741T") + .description( + "If the genome only contains one segment then this is: " + + "(mutationFrom)(position)(mutationTo)." + + "If it has more than one segment (e.g., influenza), then the sequence is contained here: " + + "(sequenceName):(mutationFrom)(position)" + + "(mutationTo)", + ), + "proportion" to NumberSchema() + .example(0.54321) + .description( + "Number of sequences with this mutation divided by the total number sequences matching the " + + "given filter criteria with non-ambiguous reads at that position", + ), + "count" to IntegerSchema() + .example(1234) + .description("Total number of sequences with this mutation matching the given sequence filter criteria"), + "sequenceName" to StringSchema() + .example("sequence1") + .description( + "The name of the segment in which the mutation occurs. Null if the genome is single-segmented.", + ), + "mutationFrom" to StringSchema() + .example("G") + .description("The nucleotide symbol in the reference genome at the position of the mutation"), + "mutationTo" to StringSchema() + .example("T") + .description("The nucleotide symbol that the mutation changes to or '-' in case of a deletion"), + "position" to IntegerSchema() + .example(29741) + .description("The position in the reference genome where the mutation occurs"), ) private fun aminoAcidMutationProportionSchema() = mapOf( - "mutation" to Schema().type("string").example("ORF1a:123").description( - "A amino acid mutation that was found in the format \"\\:\\", - ), - "proportion" to Schema().type("number").description("The proportion of sequences having the mutation."), - "count" to Schema().type("integer") - .description("The number of sequences matching having the mutation."), + "mutation" to StringSchema() + .example("ORF1a:G29741T") + .description("Of the format (sequenceName):(mutationFrom)(position)(mutationTo)"), + "proportion" to NumberSchema() + .example(0.54321) + .description( + "Number of sequences with this mutation divided by the total number sequences matching the " + + "given filter criteria with non-ambiguous reads at that position", + ), + "count" to IntegerSchema() + .example(42) + .description("Total number of sequences with this mutation matching the given sequence filter criteria"), + "sequenceName" to StringSchema() + .example("ORF1a") + .description("The name of the gene in which the mutation occurs."), + "mutationFrom" to StringSchema() + .example("G") + .description("The amino acid symbol in the reference genome at the position of the mutation"), + "mutationTo" to StringSchema() + .example("T") + .description("The amino acid symbol that the mutation changes to or '-' in case of a deletion"), + "position" to IntegerSchema() + .example(29741) + .description("The position in the reference genome where the mutation occurs"), ) private fun nucleotideInsertionSchema() = mapOf( - "insertion" to Schema().type("string") - .example("ins_segment:123:AAT") - .description("The insertion that was found."), - "count" to Schema().type("integer") - .description("The number of sequences matching having the insertion."), + "insertion" to StringSchema() + .example("ins_segment1:22204:CAGAAG") + .description( + "A nucleotide insertion in the format \"ins_(segment):(position):(insertedSymbols)\". " + + "If the pathogen has only one segment LAPIS will omit the segment name (\"ins_22204:CAGAAG\").", + ), + "count" to IntegerSchema() + .example(42) + .description("Total number of sequences with this insertion matching the given sequence filter criteria"), + "insertedSymbols" to StringSchema() + .example("CAGAAG") + .description("The nucleotide symbols that were inserted at the given position"), + "position" to IntegerSchema() + .example(22204) + .description("The position in the reference genome where the insertion occurs"), + "sequenceName" to StringSchema() + .example("segment1") + .description( + "The name of the segment in which the insertion occurs. Null if the genome is single-segmented.", + ), ) private fun aminoAcidInsertionSchema() = mapOf( - "insertion" to Schema().type("string") - .example("ins_gene:123:AAT") - .description("The insertion that was found."), - "count" to Schema().type("integer") - .description("The number of sequences matching having the insertion."), + "insertion" to StringSchema() + .example("ins_ORF1a:22204:CAGAAG") + .description("An amino acid insertion in the format \"ins_(gene):(position):(insertedSymbols)\"."), + "count" to IntegerSchema() + .description("Total number of sequences with this insertion matching the given sequence filter criteria."), + "insertedSymbols" to StringSchema() + .example("CAGAAG") + .description("The amino acid symbols that were inserted at the given position."), + "position" to IntegerSchema() + .example(22204) + .description("The position in the reference genome where the insertion occurs."), + "sequenceName" to StringSchema() + .example("ORF1a") + .description("The name of the gene in which the insertion occurs."), ) private fun nucleotideMutations() = @@ -512,9 +593,14 @@ private fun fieldsArray( private fun aggregatedOrderByFieldsEnum(databaseConfig: DatabaseConfig) = orderByFieldsEnum(databaseConfig.schema.metadata, listOf("count")) -private fun mutationsOrderByFieldsEnum() = orderByFieldsEnum(emptyList(), listOf("mutation", "count", "proportion")) +private fun mutationsOrderByFieldsEnum() = + orderByFieldsEnum( + emptyList(), + listOf("mutation", "count", "proportion", "sequenceName", "mutationFrom", "mutationTo", "position"), + ) -private fun insertionsOrderByFieldsEnum() = orderByFieldsEnum(emptyList(), listOf("insertion", "count")) +private fun insertionsOrderByFieldsEnum() = + orderByFieldsEnum(emptyList(), listOf("insertion", "count", "position", "sequenceName", "insertedSymbols")) private fun aminoAcidSequenceOrderByFieldsEnum( referenceGenomeSchema: ReferenceGenomeSchema, diff --git a/lapis2/src/main/kotlin/org/genspectrum/lapis/response/LapisResponse.kt b/lapis2/src/main/kotlin/org/genspectrum/lapis/response/LapisResponse.kt index 9cf516b0..73fdc97f 100644 --- a/lapis2/src/main/kotlin/org/genspectrum/lapis/response/LapisResponse.kt +++ b/lapis2/src/main/kotlin/org/genspectrum/lapis/response/LapisResponse.kt @@ -1,86 +1,119 @@ package org.genspectrum.lapis.response -import io.swagger.v3.oas.annotations.media.Schema import org.genspectrum.lapis.controller.CsvRecord data class NucleotideMutationResponse( - @Schema( - example = "sequenceName:G29741T", - description = "If the genome only contains one segment then this is: " + - "(nucleotide symbol in reference genome)(position in genome)(mutation's target nucleotide symbol)." + - "If it has more than one segment (e.g., influenza), then the sequence is contained here: " + - "(sequenceName):(nucleotide symbol in reference genome)(position in genome)" + - "(mutation's target nucleotide symbol)", - ) val mutation: String, - @Schema( - example = "42", - description = "Total number of sequences with this mutation matching the given sequence filter criteria", - ) val count: Int, - @Schema( - example = "0.54321", - description = "Number of sequences with this mutation divided by the total number sequences matching the " + - "given filter criteria with non-ambiguous reads at that position", - ) val proportion: Double, + val mutation: String, + val count: Int, + val proportion: Double, + val sequenceName: String?, + val mutationFrom: String, + val mutationTo: String, + val position: Int, ) : CsvRecord { - override fun getValuesList() = listOf(mutation, count.toString(), proportion.toString()) + override fun getValuesList() = + listOf( + mutation, + count.toString(), + proportion.toString(), + sequenceName ?: "", + mutationFrom, + mutationTo, + position.toString(), + ) - override fun getHeader() = arrayOf("mutation", "count", "proportion") + override fun getHeader() = + arrayOf( + "mutation", + "count", + "proportion", + "sequenceName", + "mutationFrom", + "mutationTo", + "position", + ) } data class AminoAcidMutationResponse( - @Schema( - example = "ORF1a:G29741T", - description = "(Gene):(amino acid symbol in reference genome)(position in genome)" + - "(mutation's target nucleotide symbol)", - ) val mutation: String, - @Schema( - example = "42", - description = "Total number of sequences with this mutation matching the given sequence filter criteria", - ) val count: Int, - @Schema( - example = "0.54321", - description = "Number of sequences with this mutation divided by the total number sequences matching the " + - "given filter criteria with non-ambiguous reads at that position", - ) val proportion: Double, + val mutation: String, + val count: Int, + val proportion: Double, + val sequenceName: String, + val mutationFrom: String, + val mutationTo: String, + val position: Int, ) : CsvRecord { - override fun getValuesList() = listOf(mutation, count.toString(), proportion.toString()) + override fun getValuesList() = + listOf( + mutation, + count.toString(), + proportion.toString(), + sequenceName, + mutationFrom, + mutationTo, + position.toString(), + ) - override fun getHeader() = arrayOf("mutation", "count", "proportion") + override fun getHeader() = + arrayOf( + "mutation", + "count", + "proportion", + "sequenceName", + "mutationFrom", + "mutationTo", + "position", + ) } data class NucleotideInsertionResponse( - @Schema( - example = "ins_22204:CAGAA", - description = - "|A nucleotide insertion in the format \"ins_\\?:\\:\\\". " + - "|If the pathogen has only one segment LAPIS will omit the segment name.", - ) val insertion: String, - @Schema( - example = "123", - description = "Total number of sequences with this insertion matching the given sequence filter criteria", - ) val count: Int, + val insertedSymbols: String, + val position: Int, + val sequenceName: String?, ) : CsvRecord { - override fun getValuesList() = listOf(insertion, count.toString()) + override fun getValuesList() = + listOf( + insertion, + count.toString(), + insertedSymbols, + position.toString(), + sequenceName ?: "", + ) - override fun getHeader() = arrayOf("insertion", "count") + override fun getHeader() = + arrayOf( + "insertion", + "count", + "insertedSymbols", + "position", + "sequenceName", + ) } data class AminoAcidInsertionResponse( - @Schema( - example = "ins_ORF1a:22204:CAGAA", - description = - "|A amino acid insertion in the format \"ins_\\:\\:\\\".", - ) val insertion: String, - @Schema( - example = "123", - description = "Total number of sequences with this insertion matching the given sequence filter criteria", - ) val count: Int, + val insertedSymbols: String, + val position: Int, + val sequenceName: String, ) : CsvRecord { - override fun getValuesList() = listOf(insertion, count.toString()) + override fun getValuesList() = + listOf( + insertion, + count.toString(), + insertedSymbols, + position.toString(), + sequenceName, + ) - override fun getHeader() = arrayOf("insertion", "count") + override fun getHeader() = + arrayOf( + "insertion", + "count", + "insertedSymbols", + "position", + "sequenceName", + ) } diff --git a/lapis2/src/main/kotlin/org/genspectrum/lapis/response/SiloResponse.kt b/lapis2/src/main/kotlin/org/genspectrum/lapis/response/SiloResponse.kt index 3eaa449e..988634b0 100644 --- a/lapis2/src/main/kotlin/org/genspectrum/lapis/response/SiloResponse.kt +++ b/lapis2/src/main/kotlin/org/genspectrum/lapis/response/SiloResponse.kt @@ -82,11 +82,15 @@ data class MutationData( val count: Int, val proportion: Double, val sequenceName: String, + val mutationFrom: String, + val mutationTo: String, + val position: Int, ) data class InsertionData( val count: Int, - val insertions: String, + val insertion: String, + val insertedSymbols: String, val position: Int, val sequenceName: String, ) diff --git a/lapis2/src/test/kotlin/org/genspectrum/lapis/controller/LapisControllerTest.kt b/lapis2/src/test/kotlin/org/genspectrum/lapis/controller/LapisControllerTest.kt index f6f3e295..6bfa834e 100644 --- a/lapis2/src/test/kotlin/org/genspectrum/lapis/controller/LapisControllerTest.kt +++ b/lapis2/src/test/kotlin/org/genspectrum/lapis/controller/LapisControllerTest.kt @@ -279,8 +279,19 @@ class LapisControllerTest( val data = response["data"] as List<*> val firstDataObject = data[0] as Map<*, *> - assertThat(firstDataObject.keys, hasSize(3)) - assertThat(firstDataObject.keys, containsInAnyOrder("mutation", "proportion", "count")) + assertThat(firstDataObject.keys, hasSize(7)) + assertThat( + firstDataObject.keys, + containsInAnyOrder( + "mutation", + "proportion", + "count", + "sequenceName", + "mutationFrom", + "mutationTo", + "position", + ), + ) } private fun setupMutationMock( @@ -354,8 +365,11 @@ class LapisControllerTest( val data = response["data"] as List<*> val firstDataObject = data[0] as Map<*, *> - assertThat(firstDataObject.keys, hasSize(2)) - assertThat(firstDataObject.keys, containsInAnyOrder("insertion", "count")) + assertThat(firstDataObject.keys, hasSize(5)) + assertThat( + firstDataObject.keys, + containsInAnyOrder("insertion", "count", "position", "sequenceName", "insertedSymbols"), + ) } private fun setupInsertionMock(endpoint: String) { @@ -478,13 +492,45 @@ class LapisControllerTest( .andExpect(jsonPath("\$.data[0].date").value("a date")) } - private fun someNucleotideMutationProportion() = NucleotideMutationResponse("the mutation", 42, 0.5) + private fun someNucleotideMutationProportion() = + NucleotideMutationResponse( + mutation = "the mutation", + count = 42, + proportion = 0.5, + sequenceName = "sequenceName", + mutationFrom = "G", + mutationTo = "T", + position = 29741, + ) - private fun someAminoAcidMutationProportion() = AminoAcidMutationResponse("the mutation", 42, 0.5) + private fun someAminoAcidMutationProportion() = + AminoAcidMutationResponse( + mutation = "the mutation", + count = 42, + proportion = 0.5, + sequenceName = "sequenceName", + mutationFrom = "G", + mutationTo = "T", + position = 29741, + ) - private fun someNucleotideInsertion() = NucleotideInsertionResponse("the insertion", 42) + private fun someNucleotideInsertion() = + NucleotideInsertionResponse( + insertion = "the insertion", + count = 42, + insertedSymbols = "CAGAAG", + position = 22204, + sequenceName = "sequenceName", + ) - private fun someAminoAcidInsertion() = AminoAcidInsertionResponse("the insertion", 42) + private fun someAminoAcidInsertion() = + AminoAcidInsertionResponse( + insertion = "the insertion", + count = 42, + insertedSymbols = "CAGAAG", + position = 22204, + sequenceName = "sequenceName", + ) } fun getSample(path: String): MockHttpServletRequestBuilder = get("/sample/$path") diff --git a/lapis2/src/test/kotlin/org/genspectrum/lapis/controller/MockData.kt b/lapis2/src/test/kotlin/org/genspectrum/lapis/controller/MockData.kt index f729845a..594a3010 100644 --- a/lapis2/src/test/kotlin/org/genspectrum/lapis/controller/MockData.kt +++ b/lapis2/src/test/kotlin/org/genspectrum/lapis/controller/MockData.kt @@ -204,9 +204,13 @@ object MockDataForEndpoints { siloQueryModelMockCall = { it::computeNucleotideMutationProportions }, modelData = listOf( NucleotideMutationResponse( - "sequenceName:A1234T", - 2345, - 0.987, + mutation = "sequenceName:A1234T", + count = 2345, + proportion = 0.987, + sequenceName = "sequenceName", + mutationFrom = "A", + mutationTo = "T", + position = 1234, ), ), expectedJson = """ @@ -214,17 +218,21 @@ object MockDataForEndpoints { { "mutation": "sequenceName:A1234T", "count": 2345, - "proportion": 0.987 + "proportion": 0.987, + "sequenceName": "sequenceName", + "mutationFrom": "A", + "mutationTo": "T", + "position": 1234 } ] """.trimIndent(), expectedCsv = """ - mutation,count,proportion - sequenceName:A1234T,2345,0.987 + mutation,count,proportion,sequenceName,mutationFrom,mutationTo,position + sequenceName:A1234T,2345,0.987,sequenceName,A,T,1234 """.trimIndent(), expectedTsv = """ - mutation count proportion - sequenceName:A1234T 2345 0.987 + mutation count proportion sequenceName mutationFrom mutationTo position + sequenceName:A1234T 2345 0.987 sequenceName A T 1234 """.trimIndent(), ) @@ -232,27 +240,35 @@ object MockDataForEndpoints { siloQueryModelMockCall = { it::computeAminoAcidMutationProportions }, modelData = listOf( AminoAcidMutationResponse( - "sequenceName:1234", - 2345, - 0.987, + mutation = "sequenceName:A1234T", + count = 2345, + proportion = 0.987, + sequenceName = "sequenceName", + mutationFrom = "A", + mutationTo = "T", + position = 1234, ), ), expectedJson = """ [ { - "mutation": "sequenceName:1234", + "mutation": "sequenceName:A1234T", "count": 2345, - "proportion": 0.987 + "proportion": 0.987, + "sequenceName": "sequenceName", + "mutationFrom": "A", + "mutationTo": "T", + "position": 1234 } ] """.trimIndent(), expectedCsv = """ - mutation,count,proportion - sequenceName:1234,2345,0.987 + mutation,count,proportion,sequenceName,mutationFrom,mutationTo,position + sequenceName:A1234T,2345,0.987,sequenceName,A,T,1234 """.trimIndent(), expectedTsv = """ - mutation count proportion - sequenceName:1234 2345 0.987 + mutation count proportion sequenceName mutationFrom mutationTo position + sequenceName:A1234T 2345 0.987 sequenceName A T 1234 """.trimIndent(), ) @@ -260,25 +276,31 @@ object MockDataForEndpoints { siloQueryModelMockCall = { it::getNucleotideInsertions }, modelData = listOf( NucleotideInsertionResponse( - "ins_1234:CAGAA", - 41, + insertion = "ins_1234:CAGAA", + count = 41, + insertedSymbols = "CAGAA", + position = 1234, + sequenceName = "sequenceName", ), ), expectedJson = """ [ { "insertion": "ins_1234:CAGAA", - "count": 41 + "count": 41, + "insertedSymbols": "CAGAA", + "position": 1234, + "sequenceName": "sequenceName" } ] """.trimIndent(), expectedCsv = """ - insertion,count - ins_1234:CAGAA,41 + insertion,count,insertedSymbols,position,sequenceName + ins_1234:CAGAA,41,CAGAA,1234,sequenceName """.trimIndent(), expectedTsv = """ - insertion count - ins_1234:CAGAA 41 + insertion count insertedSymbols position sequenceName + ins_1234:CAGAA 41 CAGAA 1234 sequenceName """.trimIndent(), ) @@ -286,25 +308,31 @@ object MockDataForEndpoints { siloQueryModelMockCall = { it::getAminoAcidInsertions }, modelData = listOf( AminoAcidInsertionResponse( - "ins_ORF1a:1234:CAGAA", - 41, + insertion = "ins_ORF1a:1234:CAGAA", + count = 41, + insertedSymbols = "CAGAA", + position = 1234, + sequenceName = "ORF1a", ), ), expectedJson = """ [ { "insertion": "ins_ORF1a:1234:CAGAA", - "count": 41 + "count": 41, + "insertedSymbols": "CAGAA", + "position": 1234, + "sequenceName": "ORF1a" } ] """.trimIndent(), expectedCsv = """ - insertion,count - ins_ORF1a:1234:CAGAA,41 + insertion,count,insertedSymbols,position,sequenceName + ins_ORF1a:1234:CAGAA,41,CAGAA,1234,ORF1a """.trimIndent(), expectedTsv = """ - insertion count - ins_ORF1a:1234:CAGAA 41 + insertion count insertedSymbols position sequenceName + ins_ORF1a:1234:CAGAA 41 CAGAA 1234 ORF1a """.trimIndent(), ) } diff --git a/lapis2/src/test/kotlin/org/genspectrum/lapis/model/SiloQueryModelTest.kt b/lapis2/src/test/kotlin/org/genspectrum/lapis/model/SiloQueryModelTest.kt index 82621fe4..44692f45 100644 --- a/lapis2/src/test/kotlin/org/genspectrum/lapis/model/SiloQueryModelTest.kt +++ b/lapis2/src/test/kotlin/org/genspectrum/lapis/model/SiloQueryModelTest.kt @@ -27,6 +27,24 @@ import org.hamcrest.Matchers.equalTo import org.junit.jupiter.api.BeforeEach import org.junit.jupiter.api.Test +private val someMutationData = MutationData( + mutation = "A1234B", + count = 1234, + proportion = 0.1234, + sequenceName = "sequenceName", + mutationFrom = "A", + mutationTo = "B", + position = 1234, +) + +val someInsertionData = InsertionData( + count = 42, + insertion = "ins_sequenceName:1234:ABCD", + insertedSymbols = "ABCD", + position = 1234, + sequenceName = "sequenceName", +) + class SiloQueryModelTest { @MockK lateinit var siloClientMock: SiloClient @@ -88,9 +106,7 @@ class SiloQueryModelTest { @Test fun `computeNucleotideMutationProportions ignores the segmentName if singleSegmentedSequenceFeature is enabled`() { - every { siloClientMock.sendQuery(any>>()) } returns listOf( - MutationData("A1234B", 1234, 0.1234, "someSequenceName"), - ) + every { siloClientMock.sendQuery(any>>()) } returns listOf(someMutationData) every { siloFilterExpressionMapperMock.map(any()) } returns True every { referenceGenomeSchemaMock.isSingleSegmented() } returns true @@ -98,14 +114,21 @@ class SiloQueryModelTest { MutationProportionsRequest(emptyMap(), emptyList(), emptyList(), emptyList(), emptyList()), ) - assertThat(result, equalTo(listOf(NucleotideMutationResponse("A1234B", 1234, 0.1234)))) + val expectedMutation = NucleotideMutationResponse( + mutation = "A1234B", + count = 1234, + proportion = 0.1234, + sequenceName = null, + mutationFrom = "A", + mutationTo = "B", + position = 1234, + ) + assertThat(result, equalTo(listOf(expectedMutation))) } @Test fun `computeNucleotideMutationProportions includes segmentName if singleSegmentedSequenceFeature is not enabled`() { - every { siloClientMock.sendQuery(any>>()) } returns listOf( - MutationData("A1234B", 1234, 0.1234, "someSegmentName"), - ) + every { siloClientMock.sendQuery(any>>()) } returns listOf(someMutationData) every { siloFilterExpressionMapperMock.map(any()) } returns True every { referenceGenomeSchemaMock.isSingleSegmented() } returns false @@ -113,28 +136,42 @@ class SiloQueryModelTest { MutationProportionsRequest(emptyMap(), emptyList(), emptyList(), emptyList(), emptyList()), ) - assertThat(result, equalTo(listOf(NucleotideMutationResponse("someSegmentName:A1234B", 1234, 0.1234)))) + val expectedMutation = NucleotideMutationResponse( + mutation = "sequenceName:A1234B", + count = 1234, + proportion = 0.1234, + sequenceName = "sequenceName", + mutationFrom = "A", + mutationTo = "B", + position = 1234, + ) + assertThat(result, equalTo(listOf(expectedMutation))) } @Test fun `computeAminoAcidMutationsProportions returns the sequenceName with the position`() { - every { siloClientMock.sendQuery(any>>()) } returns listOf( - MutationData("A1234B", 1234, 0.1234, "someName"), - ) + every { siloClientMock.sendQuery(any>>()) } returns listOf(someMutationData) every { siloFilterExpressionMapperMock.map(any()) } returns True val result = underTest.computeAminoAcidMutationProportions( MutationProportionsRequest(emptyMap(), emptyList(), emptyList(), emptyList(), emptyList()), ) - assertThat(result, equalTo(listOf(AminoAcidMutationResponse("someName:A1234B", 1234, 0.1234)))) + val expectedMutation = AminoAcidMutationResponse( + mutation = "sequenceName:A1234B", + count = 1234, + proportion = 0.1234, + sequenceName = "sequenceName", + mutationFrom = "A", + mutationTo = "B", + position = 1234, + ) + assertThat(result, equalTo(listOf(expectedMutation))) } @Test fun `getNucleotideInsertions ignores the field sequenceName if the nucleotide sequence has one segment`() { - every { siloClientMock.sendQuery(any>>()) } returns listOf( - InsertionData(42, "ABCD", 1234, "someSequenceName"), - ) + every { siloClientMock.sendQuery(any>>()) } returns listOf(someInsertionData) every { siloFilterExpressionMapperMock.map(any()) } returns True every { referenceGenomeSchemaMock.isSingleSegmented() } returns true @@ -149,36 +186,19 @@ class SiloQueryModelTest { ), ) - assertThat(result, equalTo(listOf(NucleotideInsertionResponse("ins_1234:ABCD", 42)))) - } - - @Test - fun `getNucleotideInsertions includes the field sequenceName if the nucleotide sequence has multiple segments`() { - every { siloClientMock.sendQuery(any>>()) } returns listOf( - InsertionData(42, "ABCD", 1234, "someSequenceName"), + val expectedInsertion = NucleotideInsertionResponse( + insertion = "ins_sequenceName:1234:ABCD", + count = 42, + insertedSymbols = "ABCD", + position = 1234, + sequenceName = null, ) - every { siloFilterExpressionMapperMock.map(any()) } returns True - every { referenceGenomeSchemaMock.isSingleSegmented() } returns false - - val result = underTest.getNucleotideInsertions( - SequenceFiltersRequest( - emptyMap(), - emptyList(), - emptyList(), - emptyList(), - emptyList(), - emptyList(), - ), - ) - - assertThat(result, equalTo(listOf(NucleotideInsertionResponse("ins_someSequenceName:1234:ABCD", 42)))) + assertThat(result, equalTo(listOf(expectedInsertion))) } @Test fun `getAminoAcidInsertions returns the sequenceName with the position`() { - every { siloClientMock.sendQuery(any>>()) } returns listOf( - InsertionData(42, "ABCD", 1234, "someGene"), - ) + every { siloClientMock.sendQuery(any>>()) } returns listOf(someInsertionData) every { siloFilterExpressionMapperMock.map(any()) } returns True val result = underTest.getAminoAcidInsertions( @@ -192,7 +212,14 @@ class SiloQueryModelTest { ), ) - assertThat(result, equalTo(listOf(AminoAcidInsertionResponse("ins_someGene:1234:ABCD", 42)))) + val expectedInsertion = AminoAcidInsertionResponse( + insertion = "ins_sequenceName:1234:ABCD", + count = 42, + insertedSymbols = "ABCD", + position = 1234, + sequenceName = "sequenceName", + ) + assertThat(result, equalTo(listOf(expectedInsertion))) } @Test diff --git a/lapis2/src/test/kotlin/org/genspectrum/lapis/silo/SiloClientTest.kt b/lapis2/src/test/kotlin/org/genspectrum/lapis/silo/SiloClientTest.kt index a1e10bc8..a99400d8 100644 --- a/lapis2/src/test/kotlin/org/genspectrum/lapis/silo/SiloClientTest.kt +++ b/lapis2/src/test/kotlin/org/genspectrum/lapis/silo/SiloClientTest.kt @@ -8,6 +8,7 @@ import org.genspectrum.lapis.request.Order import org.genspectrum.lapis.request.OrderByField import org.genspectrum.lapis.response.AggregationData import org.genspectrum.lapis.response.DetailsData +import org.genspectrum.lapis.response.InsertionData import org.genspectrum.lapis.response.MutationData import org.genspectrum.lapis.response.SequenceData import org.genspectrum.lapis.scheduler.DataVersionCacheInvalidator @@ -104,46 +105,11 @@ class SiloClientTest( ) } - @Test - fun `given server returns amino acid mutations response then response can be deserialized`() { - expectQueryRequestAndRespondWith( - response() - .withContentType(MediaType.APPLICATION_JSON_UTF_8) - .withBody( - """{ - "queryResult": [ - { - "count": 45, - "mutation": "first mutation", - "proportion": 0.9, - "sequenceName": "S" - }, - { - "count": 44, - "mutation": "second mutation", - "proportion": 0.7, - "sequenceName": "ORF" - } - ] - }""", - ), - ) - - val query = SiloQuery(SiloAction.aminoAcidMutations(), StringEquals("theColumn", "theValue")) - val result = underTest.sendQuery(query) - - assertThat(result, hasSize(2)) - assertThat( - result, - containsInAnyOrder( - MutationData("first mutation", 45, 0.9, "S"), - MutationData("second mutation", 44, 0.7, "ORF"), - ), - ) - } - - @Test - fun `given server returns nucleotide response then response can be deserialized`() { + @ParameterizedTest + @MethodSource("getMutationActions") + fun `given server returns mutations response then response can be deserialized`( + action: SiloAction>, + ) { expectQueryRequestAndRespondWith( response() .withContentType(MediaType.APPLICATION_JSON_UTF_8) @@ -151,31 +117,53 @@ class SiloClientTest( """{ "queryResult": [ { - "count": 45, - "mutation": "first mutation", - "proportion": 0.9, + "count": 51, + "mutation": "C3037T", + "mutationFrom": "C", + "mutationTo": "T", + "position": 3037, + "proportion": 1, "sequenceName": "main" }, { - "count": 44, - "mutation": "second mutation", - "proportion": 0.7, - "sequenceName": "otherSequence" + "count": 52, + "mutation": "C14408T", + "mutationFrom": "C", + "mutationTo": "T", + "position": 14408, + "proportion": 1, + "sequenceName": "main" } ] }""", ), ) - val query = SiloQuery(SiloAction.mutations(), StringEquals("theColumn", "theValue")) + val query = SiloQuery(action, StringEquals("theColumn", "theValue")) val result = underTest.sendQuery(query) assertThat(result, hasSize(2)) assertThat( result, containsInAnyOrder( - MutationData("first mutation", 45, 0.9, "main"), - MutationData("second mutation", 44, 0.7, "otherSequence"), + MutationData( + mutation = "C3037T", + count = 51, + proportion = 1.0, + sequenceName = "main", + mutationFrom = "C", + mutationTo = "T", + position = 3037, + ), + MutationData( + mutation = "C14408T", + count = 52, + proportion = 1.0, + sequenceName = "main", + mutationFrom = "C", + mutationTo = "T", + position = 14408, + ), ), ) } @@ -273,6 +261,61 @@ class SiloClientTest( ) } + @ParameterizedTest + @MethodSource("getInsertionActions") + fun `GIVEN server returns insertions response THEN response can be deserialized`( + action: SiloAction>, + ) { + expectQueryRequestAndRespondWith( + response() + .withContentType(MediaType.APPLICATION_JSON_UTF_8) + .withBody( + """{ + "queryResult": [ + { + "count": 1, + "insertedSymbols": "SGE", + "position": 143, + "insertion": "ins_S:247:SGE", + "sequenceName": "S" + }, + { + "count": 2, + "insertedSymbols": "EPE", + "position": 214, + "insertion": "ins_S:214:EPE", + "sequenceName": "S" + } + ] + }""", + ), + ) + + val query = SiloQuery(action, True) + val result = underTest.sendQuery(query) + + assertThat(result, hasSize(2)) + assertThat( + result, + containsInAnyOrder( + InsertionData( + 1, + "ins_S:247:SGE", + "SGE", + 143, + "S", + ), + InsertionData( + 2, + "ins_S:214:EPE", + "EPE", + 214, + "S", + ), + ), + ) + } + @Test fun `given server returns error in unexpected format then throws exception`() { expectQueryRequestAndRespondWith( @@ -451,6 +494,18 @@ class SiloClientTest( } companion object { + @JvmStatic + val mutationActions = listOf( + SiloAction.mutations(), + SiloAction.aminoAcidMutations(), + ) + + @JvmStatic + val insertionActions = listOf( + SiloAction.nucleotideInsertions(), + SiloAction.aminoAcidInsertions(), + ) + @JvmStatic val queriesThatShouldNotBeCached = listOf( SiloQuery(SiloAction.details(), True), diff --git a/siloLapisTests/test/aminoAcidInsertions.spec.ts b/siloLapisTests/test/aminoAcidInsertions.spec.ts index 07c2ce14..ba46434c 100644 --- a/siloLapisTests/test/aminoAcidInsertions.spec.ts +++ b/siloLapisTests/test/aminoAcidInsertions.spec.ts @@ -13,6 +13,9 @@ describe('The /aminoAcidInsertions endpoint', () => { const specificInsertion = result.data.find(insertionData => insertionData.insertion === someInsertion); expect(specificInsertion?.count).to.equal(5); + expect(specificInsertion?.insertedSymbols).to.equal('EPE'); + expect(specificInsertion?.position).to.equal(214); + expect(specificInsertion?.sequenceName).to.equal('S'); }); it('should order by specified fields', async () => { @@ -70,6 +73,9 @@ describe('The /aminoAcidInsertions endpoint', () => { const expectedFirstResultWithAminoAcidInsertion = { insertion: 'ins_ORF1a:3602:FEP', count: 1, + insertedSymbols: 'FEP', + position: 3602, + sequenceName: 'ORF1a', }; const result = await lapisClient.postAminoAcidInsertions1({ @@ -86,6 +92,7 @@ describe('The /aminoAcidInsertions endpoint', () => { const urlParams = new URLSearchParams({ country: 'Switzerland', dataFormat: 'csv', + orderBy: 'position', }); const result = await fetch(basePath + '/sample/aminoAcidInsertions?' + urlParams.toString()); @@ -93,18 +100,18 @@ describe('The /aminoAcidInsertions endpoint', () => { expect(resultText).to.contain( String.raw` -insertion,count +insertion,count,insertedSymbols,position,sequenceName `.trim() ); expect(resultText).to.contain( String.raw` -ins_ORF1a:3602:F,1 -ins_ORF1a:3602:FEP,1 -ins_S:210:IV,1 -ins_S:247:SGE,1 -ins_S:214:EPE,5 -ins_S:143:T,1 +ins_S:143:T,1,T,143,S +ins_S:210:IV,1,IV,210,S +ins_S:214:EPE,5,EPE,214,S +ins_S:247:SGE,1,SGE,247,S +ins_ORF1a:3602:F,1,F,3602,ORF1a +ins_ORF1a:3602:FEP,1,FEP,3602,ORF1a `.trim() ); }); @@ -113,6 +120,7 @@ ins_S:143:T,1 const urlParams = new URLSearchParams({ country: 'Switzerland', dataFormat: 'tsv', + orderBy: 'position', }); const result = await fetch(basePath + '/sample/aminoAcidInsertions?' + urlParams.toString()); @@ -120,18 +128,18 @@ ins_S:143:T,1 expect(resultText).to.contain( String.raw` -insertion count +insertion count insertedSymbols position sequenceName `.trim() ); expect(resultText).to.contain( String.raw` -ins_ORF1a:3602:F 1 -ins_ORF1a:3602:FEP 1 -ins_S:210:IV 1 -ins_S:247:SGE 1 -ins_S:214:EPE 5 -ins_S:143:T 1 +ins_S:143:T 1 T 143 S +ins_S:210:IV 1 IV 210 S +ins_S:214:EPE 5 EPE 214 S +ins_S:247:SGE 1 SGE 247 S +ins_ORF1a:3602:F 1 F 3602 ORF1a +ins_ORF1a:3602:FEP 1 FEP 3602 ORF1a `.trim() ); }); diff --git a/siloLapisTests/test/aminoAcidMutations.spec.ts b/siloLapisTests/test/aminoAcidMutations.spec.ts index e0e6b202..5095c4cf 100644 --- a/siloLapisTests/test/aminoAcidMutations.spec.ts +++ b/siloLapisTests/test/aminoAcidMutations.spec.ts @@ -23,6 +23,10 @@ describe('The /aminoAcidMutations endpoint', () => { ); expect(commonMutationProportion?.count).to.equal(69); expect(commonMutationProportion?.proportion).to.be.approximately(0.7340425531914894, 0.0001); + expect(commonMutationProportion?.sequenceName).to.be.equal('S'); + expect(commonMutationProportion?.mutationFrom).to.be.equal('T'); + expect(commonMutationProportion?.mutationTo).to.be.equal('K'); + expect(commonMutationProportion?.position).to.be.equal(478); }); it('should return mutation proportions for Switzerland with minProportion 0.5', async () => { @@ -85,7 +89,11 @@ describe('The /aminoAcidMutations endpoint', () => { const expectedFirstResultWithNucleotideInsertion = { count: 1, mutation: 'E:T9I', - proportion: 1.0, + mutationFrom: 'T', + mutationTo: 'I', + position: 9, + proportion: 1, + sequenceName: 'E', }; const result = await lapisClient.postAminoAcidMutations1({ @@ -102,7 +110,11 @@ describe('The /aminoAcidMutations endpoint', () => { const expectedFirstResultWithAminoAcidInsertion = { count: 1, mutation: 'N:A220V', - proportion: 1.0, + mutationFrom: 'A', + mutationTo: 'V', + position: 220, + proportion: 1, + sequenceName: 'N', }; const result = await lapisClient.postAminoAcidMutations1({ @@ -128,15 +140,15 @@ describe('The /aminoAcidMutations endpoint', () => { expect(resultText).to.contain( String.raw` -mutation,count,proportion +mutation,count,proportion,sequenceName,mutationFrom,mutationTo,position `.trim() ); expect(resultText).to.contain( String.raw` -N:A220V,1,0.058823529411764705 -S:A222V,3,0.1875 -ORF1a:A2529V,3,0.17647058823529413 +N:A220V,1,0.058823529411764705,N,A,V,220 +S:A222V,3,0.1875,S,A,V,222 +ORF1a:A2529V,3,0.17647058823529413,ORF1a,A,V,2529 `.trim() ); }); @@ -154,15 +166,15 @@ ORF1a:A2529V,3,0.17647058823529413 expect(resultText).to.contain( String.raw` -mutation count proportion +mutation count proportion sequenceName mutationFrom mutationTo position `.trim() ); expect(resultText).to.contain( String.raw` -N:A220V 1 0.058823529411764705 -S:A222V 3 0.1875 -ORF1a:A2529V 3 0.17647058823529413 +N:A220V 1 0.058823529411764705 N A V 220 +S:A222V 3 0.1875 S A V 222 +ORF1a:A2529V 3 0.17647058823529413 ORF1a A V 2529 `.trim() ); }); diff --git a/siloLapisTests/test/nucleotideInsertions.spec.ts b/siloLapisTests/test/nucleotideInsertions.spec.ts index dbbd2bd2..eaaa157e 100644 --- a/siloLapisTests/test/nucleotideInsertions.spec.ts +++ b/siloLapisTests/test/nucleotideInsertions.spec.ts @@ -13,6 +13,9 @@ describe('The /nucleotideInsertions endpoint', () => { const specificInsertion = result.data.find(insertionData => insertionData.insertion === someInsertion); expect(specificInsertion?.count).to.equal(17); + expect(specificInsertion?.insertedSymbols).to.equal('CCC'); + expect(specificInsertion?.position).to.equal(25701); + expect(specificInsertion?.sequenceName).to.be.undefined; }); it('should order by specified fields', async () => { @@ -66,11 +69,17 @@ describe('The /nucleotideInsertions endpoint', () => { expect(result.data).to.have.length(2); expect(result.data[0]).to.deep.equal({ count: 1, + insertedSymbols: 'CCC', insertion: 'ins_25701:CCC', + position: 25701, + sequenceName: undefined, }); expect(result.data[1]).to.deep.equal({ count: 1, + insertedSymbols: 'TAT', insertion: 'ins_5959:TAT', + position: 5959, + sequenceName: undefined, }); }); @@ -88,6 +97,7 @@ describe('The /nucleotideInsertions endpoint', () => { const urlParams = new URLSearchParams({ country: 'Switzerland', dataFormat: 'csv', + orderBy: 'position', }); const result = await fetch(basePath + '/sample/nucleotideInsertions?' + urlParams.toString()); @@ -95,16 +105,16 @@ describe('The /nucleotideInsertions endpoint', () => { expect(resultText).to.contain( String.raw` -insertion,count +insertion,count,insertedSymbols,position,sequenceName `.trim() ); expect(resultText).to.contain( String.raw` -ins_5959:TAT,2 -ins_22339:GCTGGT,1 -ins_22204:CAGAA,1 -ins_25701:CCC,17 +ins_5959:TAT,2,TAT,5959, +ins_22204:CAGAA,1,CAGAA,22204, +ins_22339:GCTGGT,1,GCTGGT,22339, +ins_25701:CCC,17,CCC,25701, `.trim() ); }); @@ -113,6 +123,7 @@ ins_25701:CCC,17 const urlParams = new URLSearchParams({ country: 'Switzerland', dataFormat: 'tsv', + orderBy: 'position', }); const result = await fetch(basePath + '/sample/nucleotideInsertions?' + urlParams.toString()); @@ -120,16 +131,16 @@ ins_25701:CCC,17 expect(resultText).to.contain( String.raw` -insertion count +insertion count insertedSymbols position sequenceName `.trim() ); expect(resultText).to.contain( String.raw` -ins_5959:TAT 2 -ins_22339:GCTGGT 1 -ins_22204:CAGAA 1 -ins_25701:CCC 17 +ins_5959:TAT 2 TAT 5959 +ins_22204:CAGAA 1 CAGAA 22204 +ins_22339:GCTGGT 1 GCTGGT 22339 +ins_25701:CCC 17 CCC 25701 `.trim() ); }); diff --git a/siloLapisTests/test/nucleotideMutations.spec.ts b/siloLapisTests/test/nucleotideMutations.spec.ts index 3ec20f8f..8d23168e 100644 --- a/siloLapisTests/test/nucleotideMutations.spec.ts +++ b/siloLapisTests/test/nucleotideMutations.spec.ts @@ -23,6 +23,10 @@ describe('The /nucleotideMutations endpoint', () => { ); expect(commonMutationProportion?.count).to.equal(51); expect(commonMutationProportion?.proportion).to.be.approximately(0.5204, 0.0001); + expect(commonMutationProportion?.sequenceName).to.be.undefined; + expect(commonMutationProportion?.mutationFrom).to.be.equal('G'); + expect(commonMutationProportion?.mutationTo).to.be.equal('C'); + expect(commonMutationProportion?.position).to.be.equal(28280); }); it('should return mutation proportions for Switzerland with minProportion 0.5', async () => { @@ -86,6 +90,10 @@ describe('The /nucleotideMutations endpoint', () => { count: 1, mutation: 'C241T', proportion: 1.0, + mutationFrom: 'C', + mutationTo: 'T', + position: 241, + sequenceName: undefined, }; const result = await lapisClient.postNucleotideMutations1({ @@ -103,6 +111,10 @@ describe('The /nucleotideMutations endpoint', () => { count: 1, mutation: 'G210T', proportion: 1.0, + mutationFrom: 'G', + mutationTo: 'T', + position: 210, + sequenceName: undefined, }; const result = await lapisClient.postNucleotideMutations1({ @@ -128,15 +140,15 @@ describe('The /nucleotideMutations endpoint', () => { expect(resultText).to.contain( String.raw` -mutation,count,proportion +mutation,count,proportion,sequenceName,mutationFrom,mutationTo,position `.trim() ); expect(resultText).to.contain( String.raw` -C7029T,1,0.0625 -C71-,1,0.058823529411764705 -C7124T,2,0.11764705882352941 +C7029T,1,0.0625,,C,T,7029 +C71-,1,0.058823529411764705,,C,-,71 +C7124T,2,0.11764705882352941,,C,T,7124 `.trim() ); }); @@ -154,15 +166,15 @@ C7124T,2,0.11764705882352941 expect(resultText).to.contain( String.raw` -mutation count proportion +mutation count proportion sequenceName mutationFrom mutationTo position `.trim() ); expect(resultText).to.contain( String.raw` -C7029T 1 0.0625 -C71- 1 0.058823529411764705 -C7124T 2 0.11764705882352941 +C7029T 1 0.0625 C T 7029 +C71- 1 0.058823529411764705 C - 71 +C7124T 2 0.11764705882352941 C T 7124 `.trim() ); });