examples/pyomadb-examples.ipynb

{
 "cells": [
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# PyOMADB Examples\n",
    "-- Alex Warwick Vesztrocy, December 2018\n",
    "\n",
    "This notebook shows the examples from the paper, as written by Klara Kaleb, using the Python library PyOMADB instead of the OMADB R package."
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "The PyOMADB package can be installed from the PyPI -- as `omadb`. There are a few optional dependencies:\n",
    "- `dendropy` -- for dendropy trees\n",
    "- `ete3` -- for ETE tree visualisation\n",
    "- `goea` -- to perform GO enrichment analyses using GOATOOLS\n",
    "- `hog_analysis` -- to perform analysis on hierarchical orthologous groups (HOGs)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Collecting omadb\n",
      "  Downloading https://files.pythonhosted.org/packages/60/d8/970f2718ece1c589fe3f8ed57a1666425ba61f8495e1b0496411bbb461db/omadb-1.0.14-py3-none-any.whl\n",
      "Requirement already satisfied: property-manager in /usr/local/miniconda3/lib/python3.6/site-packages (from omadb)\n",
      "Requirement already satisfied: pprint in /usr/local/miniconda3/lib/python3.6/site-packages (from omadb)\n",
      "Requirement already satisfied: tqdm in /usr/local/miniconda3/lib/python3.6/site-packages (from omadb)\n",
      "Requirement already satisfied: pandas in /usr/local/miniconda3/lib/python3.6/site-packages (from omadb)\n",
      "Requirement already satisfied: requests-cache in /usr/local/miniconda3/lib/python3.6/site-packages (from omadb)\n",
      "Requirement already satisfied: requests in /usr/local/miniconda3/lib/python3.6/site-packages (from omadb)\n",
      "Requirement already satisfied: appdirs in /usr/local/miniconda3/lib/python3.6/site-packages (from omadb)\n",
      "Requirement already satisfied: humanfriendly>=1.44.7 in /usr/local/miniconda3/lib/python3.6/site-packages (from property-manager->omadb)\n",
      "Requirement already satisfied: verboselogs>=1.1 in /usr/local/miniconda3/lib/python3.6/site-packages (from property-manager->omadb)\n",
      "Requirement already satisfied: python-dateutil>=2 in /usr/local/miniconda3/lib/python3.6/site-packages (from pandas->omadb)\n",
      "Requirement already satisfied: pytz>=2011k in /usr/local/miniconda3/lib/python3.6/site-packages (from pandas->omadb)\n",
      "Requirement already satisfied: numpy>=1.9.0 in /usr/local/miniconda3/lib/python3.6/site-packages (from pandas->omadb)\n",
      "Requirement already satisfied: chardet<3.1.0,>=3.0.2 in /usr/local/miniconda3/lib/python3.6/site-packages (from requests->omadb)\n",
      "Requirement already satisfied: idna<2.7,>=2.5 in /usr/local/miniconda3/lib/python3.6/site-packages (from requests->omadb)\n",
      "Requirement already satisfied: urllib3<1.23,>=1.21.1 in /usr/local/miniconda3/lib/python3.6/site-packages (from requests->omadb)\n",
      "Requirement already satisfied: certifi>=2017.4.17 in /usr/local/miniconda3/lib/python3.6/site-packages (from requests->omadb)\n",
      "Requirement already satisfied: six>=1.5 in /usr/local/miniconda3/lib/python3.6/site-packages (from python-dateutil>=2->pandas->omadb)\n",
      "Installing collected packages: omadb\n",
      "Successfully installed omadb-1.0.14\n",
      "\u001b[33mYou are using pip version 9.0.1, however version 18.1 is available.\n",
      "You should consider upgrading via the 'pip install --upgrade pip' command.\u001b[0m\n"
     ]
    }
   ],
   "source": [
    "!pip install omadb[dendropy,ete3,goea]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Now that the package is installed, we can load it."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {},
   "outputs": [],
   "source": [
    "from omadb import Client"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Then the client can be initialised as such:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {},
   "outputs": [],
   "source": [
    "c = Client()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Note: by default, the client will cache 10,000 `GET` requests in memory. If you wish to raise this, or lower it, this needs to be done prior to initialisation of the client by altering `Client.RAMCACHE_SIZE`."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "10000"
      ]
     },
     "execution_count": 4,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "Client.RAMCACHE_SIZE"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "---"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Example 1 -- Retrieving single protein entries"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "metadata": {},
   "outputs": [],
   "source": [
    "prot_id = 'P53_RAT'\n",
    "\n",
    "r = c.proteins[prot_id]  # Can also be called as c.proteins.info(prot_id)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 6,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/plain": [
       "{'alternative_isoforms_urls': [],\n",
       " 'canonicalid': 'P53_RAT',\n",
       " 'cdna': 'ATGGAGGATTCACAGTCGGATATGAGCATCGAGCTCCCTCTGAGTCAGGAGACATTTTCATGCTTATGGAAACTTCTTCCTCCAGATGATATTCTGCCCACCACAGCGACAGGGTCACCTAATTCCATGGAAGATCTGTTCCTGCCCCAGGATGTTGCAGAGTTGTTAGAAGGCCCAGAGGAAGCCCTCCAAGTGTCAGCTCCTGCAGCACAGGAACCTGGAACTGAGGCCCCTGCACCCGTGGCCCCTGCTTCAGCTACACCGTGGCCTCTGTCATCTTCCGTCCCTTCTCAAAAAACTTACCAAGGCAACTATGGCTTCCACCTGGGCTTCCTGCAGTCAGGGACAGCCAAGTCTGTTATGTGCACGTACTCAATTTCCCTCAATAAGCTGTTCTGCCAGCTGGCGAAGACATGCCCTGTGCAGTTGTGGGTCACCTCCACACCTCCACCTGGTACCCGTGTCCGTGCCATGGCCATCTACAAGAAGTCACAACACATGACTGAGGTCGTGAGACGCTGCCCCCACCATGAGCGTTGCTCTGATGGTGACGGCCTGGCTCCTCCCCAACATCTTATCCGGGTGGAAGGAAATCCGTATGCTGAGTATCTGGACGACAGGCAGACTTTTCGGCACAGCGTGGTGGTACCGTATGAGCCACCTGAGGTCGGCTCCGACTATACCACTATCCACTACAAGTACATGTGCAACAGCTCCTGCATGGGGGGCATGAACCGCCGGCCCATCCTTACCATCATCACGCTGGAAGACTCCAGTGGGAATCTTCTGGGACGGGACAGCTTTGAGGTTCGTGTTTGTGCCTGTCCTGGGAGAGACCGTCGGACAGAGGAAGAAAATTTCCGCAAAAAAGAAGAGCATTGCCCGGAGCTGCCCCCAGGGAGTGCAAAGAGAGCACTGCCCACCAGCACAAGCTCCTCTCCCCAGCAAAAGAAAAAACCACTCGATGGAGAATATTTCACCCTTAAGATCCGTGGGCGTGAGCGCTTCGAGATGTTCCGAGAGCTGAATGAGGCCTTGGAATTAAAGGATGCCCGTGCTGCCGAGGAGTCAGGAGACAGCAGGGCTCACTCCAGCTACCCGAAGACCAAGAAGGGCCAGTCTACGTCCCGCCATAAAAAACCAATGATCAAGAAAGTGGGGCCTGACTCAGACTGA',\n",
       " 'chromosome': '10',\n",
       " 'domains': <API Request /protein/7916807/domains/>,\n",
       " 'entry_nr': 7916807,\n",
       " 'entry_url': <API Request /protein/7916807/>,\n",
       " 'hog_levels': ['Murinae',\n",
       "                'Muroidea',\n",
       "                'Myomorpha',\n",
       "                'Rodentia',\n",
       "                'Glires',\n",
       "                'Euarchontoglires',\n",
       "                'Boreoeutheria',\n",
       "                'Eutheria',\n",
       "                'Theria',\n",
       "                'Mammalia',\n",
       "                'Amniota',\n",
       "                'Tetrapoda',\n",
       "                'Sarcopterygii',\n",
       "                'Euteleostomi',\n",
       "                'Vertebrata',\n",
       "                'Chordata'],\n",
       " 'homoeologs': None,\n",
       " 'is_main_isoform': True,\n",
       " 'locus': {'end': 56198000, 'start': 56193866, 'strand': 1},\n",
       " 'oma_group': 789321,\n",
       " 'oma_group_url': <API Request /group/789321/>,\n",
       " 'oma_hog_id': 'HOG:0372238.2a.2a.2b',\n",
       " 'oma_hog_members': <API Request /hog/HOG:0372238.2a.2a.2b/members/>,\n",
       " 'omaid': 'RATNO03710',\n",
       " 'ontology': <API Request /protein/7916807/ontology/>,\n",
       " 'orthologs': <API Request /protein/7916807/orthologs/>,\n",
       " 'roothog_id': 372238,\n",
       " 'sequence': 'MEDSQSDMSIELPLSQETFSCLWKLLPPDDILPTTATGSPNSMEDLFLPQDVAELLEGPEEALQVSAPAAQEPGTEAPAPVAPASATPWPLSSSVPSQKTYQGNYGFHLGFLQSGTAKSVMCTYSISLNKLFCQLAKTCPVQLWVTSTPPPGTRVRAMAIYKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNPYAEYLDDRQTFRHSVVVPYEPPEVGSDYTTIHYKYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENFRKKEEHCPELPPGSAKRALPTSTSSSPQQKKKPLDGEYFTLKIRGRERFEMFRELNEALELKDARAAEESGDSRAHSSYPKTKKGQSTSRHKKPMIKKVGPDSD',\n",
       " 'sequence_length': 391,\n",
       " 'sequence_md5': '6b5c5b7576ed037be819e56589e00c53',\n",
       " 'xref': <API Request /protein/7916807/xref/>}"
      ]
     },
     "execution_count": 6,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "r"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "It is then possible to access any of the information on this protein entry, by using attribute or key retrieval. For example,"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/plain": [
       "'ATGGAGGATTCACAGTCGGATATGAGCATCGAGCTCCCTCTGAGTCAGGAGACATTTTCATGCTTATGGAAACTTCTTCCTCCAGATGATATTCTGCCCACCACAGCGACAGGGTCACCTAATTCCATGGAAGATCTGTTCCTGCCCCAGGATGTTGCAGAGTTGTTAGAAGGCCCAGAGGAAGCCCTCCAAGTGTCAGCTCCTGCAGCACAGGAACCTGGAACTGAGGCCCCTGCACCCGTGGCCCCTGCTTCAGCTACACCGTGGCCTCTGTCATCTTCCGTCCCTTCTCAAAAAACTTACCAAGGCAACTATGGCTTCCACCTGGGCTTCCTGCAGTCAGGGACAGCCAAGTCTGTTATGTGCACGTACTCAATTTCCCTCAATAAGCTGTTCTGCCAGCTGGCGAAGACATGCCCTGTGCAGTTGTGGGTCACCTCCACACCTCCACCTGGTACCCGTGTCCGTGCCATGGCCATCTACAAGAAGTCACAACACATGACTGAGGTCGTGAGACGCTGCCCCCACCATGAGCGTTGCTCTGATGGTGACGGCCTGGCTCCTCCCCAACATCTTATCCGGGTGGAAGGAAATCCGTATGCTGAGTATCTGGACGACAGGCAGACTTTTCGGCACAGCGTGGTGGTACCGTATGAGCCACCTGAGGTCGGCTCCGACTATACCACTATCCACTACAAGTACATGTGCAACAGCTCCTGCATGGGGGGCATGAACCGCCGGCCCATCCTTACCATCATCACGCTGGAAGACTCCAGTGGGAATCTTCTGGGACGGGACAGCTTTGAGGTTCGTGTTTGTGCCTGTCCTGGGAGAGACCGTCGGACAGAGGAAGAAAATTTCCGCAAAAAAGAAGAGCATTGCCCGGAGCTGCCCCCAGGGAGTGCAAAGAGAGCACTGCCCACCAGCACAAGCTCCTCTCCCCAGCAAAAGAAAAAACCACTCGATGGAGAATATTTCACCCTTAAGATCCGTGGGCGTGAGCGCTTCGAGATGTTCCGAGAGCTGAATGAGGCCTTGGAATTAAAGGATGCCCGTGCTGCCGAGGAGTCAGGAGACAGCAGGGCTCACTCCAGCTACCCGAAGACCAAGAAGGGCCAGTCTACGTCCCGCCATAAAAAACCAATGATCAAGAAAGTGGGGCCTGACTCAGACTGA'"
      ]
     },
     "execution_count": 7,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "r.cdna"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/plain": [
       "'ATGGAGGATTCACAGTCGGATATGAGCATCGAGCTCCCTCTGAGTCAGGAGACATTTTCATGCTTATGGAAACTTCTTCCTCCAGATGATATTCTGCCCACCACAGCGACAGGGTCACCTAATTCCATGGAAGATCTGTTCCTGCCCCAGGATGTTGCAGAGTTGTTAGAAGGCCCAGAGGAAGCCCTCCAAGTGTCAGCTCCTGCAGCACAGGAACCTGGAACTGAGGCCCCTGCACCCGTGGCCCCTGCTTCAGCTACACCGTGGCCTCTGTCATCTTCCGTCCCTTCTCAAAAAACTTACCAAGGCAACTATGGCTTCCACCTGGGCTTCCTGCAGTCAGGGACAGCCAAGTCTGTTATGTGCACGTACTCAATTTCCCTCAATAAGCTGTTCTGCCAGCTGGCGAAGACATGCCCTGTGCAGTTGTGGGTCACCTCCACACCTCCACCTGGTACCCGTGTCCGTGCCATGGCCATCTACAAGAAGTCACAACACATGACTGAGGTCGTGAGACGCTGCCCCCACCATGAGCGTTGCTCTGATGGTGACGGCCTGGCTCCTCCCCAACATCTTATCCGGGTGGAAGGAAATCCGTATGCTGAGTATCTGGACGACAGGCAGACTTTTCGGCACAGCGTGGTGGTACCGTATGAGCCACCTGAGGTCGGCTCCGACTATACCACTATCCACTACAAGTACATGTGCAACAGCTCCTGCATGGGGGGCATGAACCGCCGGCCCATCCTTACCATCATCACGCTGGAAGACTCCAGTGGGAATCTTCTGGGACGGGACAGCTTTGAGGTTCGTGTTTGTGCCTGTCCTGGGAGAGACCGTCGGACAGAGGAAGAAAATTTCCGCAAAAAAGAAGAGCATTGCCCGGAGCTGCCCCCAGGGAGTGCAAAGAGAGCACTGCCCACCAGCACAAGCTCCTCTCCCCAGCAAAAGAAAAAACCACTCGATGGAGAATATTTCACCCTTAAGATCCGTGGGCGTGAGCGCTTCGAGATGTTCCGAGAGCTGAATGAGGCCTTGGAATTAAAGGATGCCCGTGCTGCCGAGGAGTCAGGAGACAGCAGGGCTCACTCCAGCTACCCGAAGACCAAGAAGGGCCAGTCTACGTCCCGCCATAAAAAACCAATGATCAAGAAAGTGGGGCCTGACTCAGACTGA'"
      ]
     },
     "execution_count": 8,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "r['cdna']"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Information that requires another load from the database shows up as \"`<API Request ...>`\" in the representation of the result, above. If using dictionary-style access, these need to be called. For example, when accessing the orthologue information:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "metadata": {},
   "outputs": [],
   "source": [
    "orth = r['orthologs']()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "However, if accessing via attributes this is lazily loaded in the background:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 10,
   "metadata": {},
   "outputs": [],
   "source": [
    "orth = r.orthologs"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "---"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Example 2 -- Sequence to HOG, to HOG Members, to GO Annotations"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "The idea here is to find a HOG for a given protein sequence, through the mapping procedure provided by the OMA REST API. If we start with the following sequence,"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 11,
   "metadata": {},
   "outputs": [],
   "source": [
    "seq = 'MKLVFLVLLFLGALGLCLAGRRRSVQWCAVSQPEATKCFQWQRNMRKVRGPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGGSFQLNELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCVPGADKGQFPNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGFSRVPPRIDSGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWSGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQTGSCKFDEYFSQSCAPGSDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVSRMDKVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSETKNLLFNDNTECLARLHGKTTYEKYLGPQYVAGITNLKKCSTSPLLEACEFLRK'"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "It is possible to map this to the an OMA protein entry using:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 12,
   "metadata": {},
   "outputs": [],
   "source": [
    "r = c.proteins.search(seq)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 13,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/plain": [
       "{'identified_by': 'exact match',\n",
       " 'query': 'MKLVFLVLLFLGALGLCLAGRRRSVQWCAVSQPEATKCFQWQRNMRKVRGPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGGSFQLNELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCVPGADKGQFPNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGFSRVPPRIDSGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWSGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQTGSCKFDEYFSQSCAPGSDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVSRMDKVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSETKNLLFNDNTECLARLHGKTTYEKYLGPQYVAGITNLKKCSTSPLLEACEFLRK',\n",
       " 'targets': [{'alternative_isoforms_urls': [],\n",
       " 'canonicalid': 'TRFL_HUMAN',\n",
       " 'cdna': 'ATGAAACTTGTCTTCCTCGTCCTGCTGTTCCTCGGGGCCCTCGGACTGTGTCTGGCTGGCCGTAGGAGGAGTGTTCAGTGGTGCGCCGTATCCCAACCCGAGGCCACAAAATGCTTCCAATGGCAAAGGAATATGAGAAAAGTGCGTGGCCCTCCTGTCAGCTGCATAAAGAGAGACTCCCCCATCCAGTGTATCCAGGCCATTGCGGAAAACAGGGCCGATGCTGTGACCCTTGATGGTGGTTTCATATACGAGGCAGGCCTGGCCCCCTACAAACTGCGACCTGTAGCGGCGGAAGTCTACGGGACCGAAAGACAGCCACGAACTCACTATTATGCCGTGGCTGTGGTGAAGAAGGGCGGCAGCTTTCAGCTGAACGAACTGCAAGGTCTGAAGTCCTGCCACACAGGCCTTCGCAGGACCGCTGGATGGAATGTCCCTATAGGGACACTTCGTCCATTCTTGAATTGGACGGGTCCACCTGAGCCCATTGAGGCAGCTGTGGCCAGGTTCTTCTCAGCCAGCTGTGTTCCCGGTGCAGATAAAGGACAGTTCCCCAACCTGTGTCGCCTGTGTGCGGGGACAGGGGAAAACAAATGTGCCTTCTCCTCCCAGGAACCGTACTTCAGCTACTCTGGTGCCTTCAAGTGTCTGAGAGACGGGGCTGGAGACGTGGCTTTTATCAGAGAGAGCACAGTGTTTGAGGACCTGTCAGACGAGGCTGAAAGGGACGAGTATGAGTTACTCTGCCCAGACAACACTCGGAAGCCAGTGGACAAGTTCAAAGACTGCCATCTGGCCCGGGTCCCTTCTCATGCCGTTGTGGCACGAAGTGTGAATGGCAAGGAGGATGCCATCTGGAATCTTCTCCGCCAGGCACAGGAAAAGTTTGGAAAGGACAAGTCACCGAAATTCCAGCTCTTTGGCTCCCCTAGTGGGCAGAAAGATCTGCTGTTCAAGGACTCTGCCATTGGGTTTTCGAGGGTGCCCCCGAGGATAGATTCTGGGCTGTACCTTGGCTCCGGCTACTTCACTGCCATCCAGAACTTGAGGAAAAGTGAGGAGGAAGTGGCTGCCCGGCGTGCGCGGGTCGTGTGGTGTGCGGTGGGCGAGCAGGAGCTGCGCAAGTGTAACCAGTGGAGTGGCTTGAGCGAAGGCAGCGTGACCTGCTCCTCGGCCTCCACCACAGAGGACTGCATCGCCCTGGTGCTGAAAGGAGAAGCTGATGCCATGAGTTTGGATGGAGGATATGTGTACACTGCAGGCAAATGTGGTTTGGTGCCTGTCCTGGCAGAGAACTACAAATCCCAACAAAGCAGTGACCCTGATCCTAACTGTGTGGATAGACCTGTGGAAGGATATCTTGCTGTGGCGGTGGTTAGGAGATCAGACACTAGCCTTACCTGGAACTCTGTGAAAGGCAAGAAGTCCTGCCACACCGCCGTGGACAGGACTGCAGGCTGGAATATCCCCATGGGCCTGCTCTTCAACCAGACGGGCTCCTGCAAATTTGATGAATATTTCAGTCAAAGCTGTGCCCCTGGGTCTGACCCGAGATCTAATCTCTGTGCTCTGTGTATTGGCGACGAGCAGGGTGAGAATAAGTGCGTGCCCAACAGCAACGAGAGATACTACGGCTACACTGGGGCTTTCCGGTGCCTGGCTGAGAATGCTGGAGACGTTGCATTTGTGAAAGATGTCACTGTCTTGCAGAACACTGATGGAAATAACAATGAGGCATGGGCTAAGGATTTGAAGCTGGCAGACTTTGCGCTGCTGTGCCTCGATGGCAAACGGAAGCCTGTGACTGAGGCTAGAAGCTGCCATCTTGCCATGGCCCCGAATCATGCCGTGGTGTCTCGGATGGATAAGGTGGAACGCCTGAAACAGGTGTTGCTCCACCAACAGGCTAAATTTGGGAGAAATGGATCTGACTGCCCGGACAAGTTTTGCTTATTCCAGTCTGAAACCAAAAACCTTCTGTTCAATGACAACACTGAGTGTCTGGCCAGACTCCATGGCAAAACAACATATGAAAAATATTTGGGACCACAGTATGTCGCAGGCATTACTAATCTGAAAAAGTGCTCAACCTCCCCCCTCCTGGAAGCCTGTGAATTCCTCAGGAAGTAA',\n",
       " 'chromosome': '3',\n",
       " 'domains': <API Request /protein/8087255/domains/>,\n",
       " 'entry_nr': 8087255,\n",
       " 'entry_url': <API Request /protein/8087255/>,\n",
       " 'hog_levels': ['Homininae',\n",
       "                'Hominidae',\n",
       "                'Hominoidea',\n",
       "                'Catarrhini',\n",
       "                'Simiiformes',\n",
       "                'Haplorrhini',\n",
       "                'Primates',\n",
       "                'Euarchontoglires',\n",
       "                'Boreoeutheria',\n",
       "                'Eutheria',\n",
       "                'Theria',\n",
       "                'Mammalia',\n",
       "                'Amniota',\n",
       "                'Tetrapoda',\n",
       "                'Sarcopterygii',\n",
       "                'Euteleostomi',\n",
       "                'Vertebrata',\n",
       "                'Chordata',\n",
       "                'Deuterostomia',\n",
       "                'Bilateria',\n",
       "                'Eumetazoa',\n",
       "                'Metazoa',\n",
       "                'Opisthokonta',\n",
       "                'Eukaryota'],\n",
       " 'homoeologs': None,\n",
       " 'is_main_isoform': True,\n",
       " 'locus': {'end': 46464867, 'start': 46436195, 'strand': -1},\n",
       " 'oma_group': 827039,\n",
       " 'oma_group_url': <API Request /group/827039/>,\n",
       " 'oma_hog_id': 'HOG:0413862.1a.1b',\n",
       " 'oma_hog_members': <API Request /hog/HOG:0413862.1a.1b/members/>,\n",
       " 'omaid': 'HUMAN20795',\n",
       " 'ontology': <API Request /protein/8087255/ontology/>,\n",
       " 'orthologs': <API Request /protein/8087255/orthologs/>,\n",
       " 'roothog_id': 413862,\n",
       " 'sequence': 'MKLVFLVLLFLGALGLCLAGRRRSVQWCAVSQPEATKCFQWQRNMRKVRGPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGGSFQLNELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCVPGADKGQFPNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGFSRVPPRIDSGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWSGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQTGSCKFDEYFSQSCAPGSDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVSRMDKVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSETKNLLFNDNTECLARLHGKTTYEKYLGPQYVAGITNLKKCSTSPLLEACEFLRK',\n",
       " 'sequence_length': 710,\n",
       " 'sequence_md5': '49350ec6dd02aabc8eb8cabc10476a4f',\n",
       " 'xref': <API Request /protein/8087255/xref/>}]}"
      ]
     },
     "execution_count": 13,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "r"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "From the results above, we can see that the matches were identified as _exact_ matches. This means that they are 100% identical to the query sequence.\n",
    "\n",
    "Now, let's see how many targets we have matched:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 14,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "1"
      ]
     },
     "execution_count": 14,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "len(r.targets)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Here we have matched a single target. Let's find its OMA ID, canonical ID and the HOG that it belongs to."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 15,
   "metadata": {},
   "outputs": [],
   "source": [
    "e = r.targets[0]"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 16,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "'HUMAN20795'"
      ]
     },
     "execution_count": 16,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "e.omaid"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 17,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "'TRFL_HUMAN'"
      ]
     },
     "execution_count": 17,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "e.canonicalid"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 18,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "'HOG:0413862.1a.1b'"
      ]
     },
     "execution_count": 18,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "e.oma_hog_id"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Next, we want to access all members from this HOG. This can be done in two ways."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 19,
   "metadata": {},
   "outputs": [],
   "source": [
    "hog = e.oma_hog_members\n",
    "hog_members = hog.members\n",
    "\n",
    "# Alternative:\n",
    "hog_members = c.hogs.members(e.oma_hog_id)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "We can then see which level this HOG is at, by accessing:"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 20,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "'Mammalia'"
      ]
     },
     "execution_count": 20,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "hog.level"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Note, it is also possible to go directly to the HOG members from a protein entry as well as a HOG ID."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 21,
   "metadata": {},
   "outputs": [],
   "source": [
    "hog_members = c.hogs.members('TRFL_HUMAN')"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Finally, let's find the GO annotations for the members of this HOG at the _Eukaryota_ level. We can then perform a GO enrichment analysis (GOEA) in order to see if this group, at the _Mammalia_ level, is enriched in any particular GO terms.\n",
    "\n",
    "This defines our background set of genes in our GOEA.\n",
    "\n",
    "We can use the GOATOOLs library to perform this analysis. There is handy functionality in the PyOMADB library to load this automatically for us -- it can even filter to a desired aspect of the GO."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 22,
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "Retrieving GO: 100%|██████████| 263/263 [00:38<00:00,  6.75it/s]\n"
     ]
    },
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "/var/folders/h9/3pbgfw_n4r53rndnhmrgn3lh0000gn/T/tmp5o_aywsx.obo: fmt(1.2) rel(2018-12-18) 47,369 GO Terms\n",
      "fisher module not installed.  Falling back on scipy.stats.fisher_exact\n",
      "100%    263 of    263 population items found in association\n"
     ]
    },
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "Propagating term counts to parents ..\n"
     ]
    }
   ],
   "source": [
    "euk_hog_members = c.hogs.members('TRFL_HUMAN', level='Eukaryota')\n",
    "\n",
    "background = [e.omaid for e in euk_hog_members]\n",
    "\n",
    "goea = c.entries.gene_ontology(background,         # Background list of IDs\n",
    "                               aspect='BP',        # Filtering (optional)\n",
    "                               as_goatools=True,   # To return GOATOOLS GOEA object\n",
    "                               progress=True,      # Show progress of GO retrieval\n",
    "                               methods=['fdr_bh']) # Passed to GOATOOLS (methods for GOEA) "
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Our foreground set is then the genes that are defined in the HOG at the level of _Mammalia_."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 23,
   "metadata": {},
   "outputs": [],
   "source": [
    "foreground = [e.omaid for e in hog_members]"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 24,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "100%     40 of     40 study items found in association\n",
      "100%     40 of     40 study items found in population(263)\n",
      "Calculating 421 uncorrected p-values using fisher_scipy_stats\n",
      "     421 GO terms are associated with    227 of    263 population items\n",
      "     272 GO terms are associated with     39 of     40 study items\n",
      "     280 GO terms found significant (< 0.05=alpha) after multitest correction: statsmodels fdr_bh\n"
     ]
    }
   ],
   "source": [
    "results = goea.run_study(foreground)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 25,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "GO\tNS\tenrichment\tname\tratio_in_study\tratio_in_pop\tp_uncorrected\tdepth\tstudy_count\tp_fdr_bh\tstudy_items\n",
      "GO:1900228\tBP\te\tregulation of single-species biofilm formation in or on host organism\t39/40\t39/263\t6.63e-46\t5\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0043900\tBP\te\tregulation of multi-organism process\t39/40\t39/263\t6.63e-46\t3\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0032101\tBP\te\tregulation of response to external stimulus\t39/40\t39/263\t6.63e-46\t4\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1903011\tBP\te\tnegative regulation of bone development\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0002682\tBP\te\tregulation of immune system process\t39/40\t39/263\t6.63e-46\t3\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0030501\tBP\te\tpositive regulation of bone mineralization\t39/40\t39/263\t6.63e-46\t7\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1902105\tBP\te\tregulation of leukocyte differentiation\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0002831\tBP\te\tregulation of response to biotic stimulus\t39/40\t39/263\t6.63e-46\t4\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1900157\tBP\te\tregulation of bone mineralization involved in bone maturation\t39/40\t39/263\t6.63e-46\t7\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0043903\tBP\te\tregulation of symbiosis, encompassing mutualism through parasitism\t39/40\t39/263\t6.63e-46\t4\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0002832\tBP\te\tnegative regulation of response to biotic stimulus\t39/40\t39/263\t6.63e-46\t5\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1903012\tBP\te\tpositive regulation of bone development\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0045667\tBP\te\tregulation of osteoblast differentiation\t39/40\t39/263\t6.63e-46\t5\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0045670\tBP\te\tregulation of osteoclast differentiation\t39/40\t39/263\t6.63e-46\t8\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0031665\tBP\te\tnegative regulation of lipopolysaccharide-mediated signaling pathway\t39/40\t39/263\t6.63e-46\t7\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1903010\tBP\te\tregulation of bone development\t39/40\t39/263\t6.63e-46\t5\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:2001204\tBP\te\tregulation of osteoclast development\t39/40\t39/263\t6.63e-46\t9\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0032102\tBP\te\tnegative regulation of response to external stimulus\t39/40\t39/263\t6.63e-46\t5\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0032501\tBP\te\tmulticellular organismal process\t39/40\t39/263\t6.63e-46\t1\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0030278\tBP\te\tregulation of ossification    \t39/40\t39/263\t6.63e-46\t4\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0060349\tBP\te\tbone morphogenesis            \t39/40\t39/263\t6.63e-46\t4\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0070167\tBP\te\tregulation of biomineral tissue development\t39/40\t39/263\t6.63e-46\t5\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0001818\tBP\te\tnegative regulation of cytokine production\t39/40\t39/263\t6.63e-46\t5\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0032680\tBP\te\tregulation of tumor necrosis factor production\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0001817\tBP\te\tregulation of cytokine production\t39/40\t39/263\t6.63e-46\t4\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0002683\tBP\te\tnegative regulation of immune system process\t39/40\t39/263\t6.63e-46\t4\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0045669\tBP\te\tpositive regulation of osteoblast differentiation\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0001503\tBP\te\tossification                  \t39/40\t39/263\t6.63e-46\t2\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0045778\tBP\te\tpositive regulation of ossification\t39/40\t39/263\t6.63e-46\t5\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0031664\tBP\te\tregulation of lipopolysaccharide-mediated signaling pathway\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0045637\tBP\te\tregulation of myeloid cell differentiation\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1900229\tBP\te\tnegative regulation of single-species biofilm formation in or on host organism\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0033688\tBP\te\tregulation of osteoblast proliferation\t39/40\t39/263\t6.63e-46\t5\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0002761\tBP\te\tregulation of myeloid leukocyte differentiation\t39/40\t39/263\t6.63e-46\t7\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:2000308\tBP\te\tnegative regulation of tumor necrosis factor (ligand) superfamily member 11 production\t39/40\t39/263\t6.63e-46\t7\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0030500\tBP\te\tregulation of bone mineralization\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1900159\tBP\te\tpositive regulation of bone mineralization involved in bone maturation\t39/40\t39/263\t6.63e-46\t8\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1900190\tBP\te\tregulation of single-species biofilm formation\t39/40\t39/263\t6.63e-46\t4\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1903556\tBP\te\tnegative regulation of tumor necrosis factor superfamily cytokine production\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:2000307\tBP\te\tregulation of tumor necrosis factor (ligand) superfamily member 11 production\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1903707\tBP\te\tnegative regulation of hemopoiesis\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1900191\tBP\te\tnegative regulation of single-species biofilm formation\t39/40\t39/263\t6.63e-46\t5\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1902106\tBP\te\tnegative regulation of leukocyte differentiation\t39/40\t39/263\t6.63e-46\t7\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1902732\tBP\te\tpositive regulation of chondrocyte proliferation\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0043901\tBP\te\tnegative regulation of multi-organism process\t39/40\t39/263\t6.63e-46\t4\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0002762\tBP\te\tnegative regulation of myeloid leukocyte differentiation\t39/40\t39/263\t6.63e-46\t8\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051241\tBP\te\tnegative regulation of multicellular organismal process\t39/40\t39/263\t6.63e-46\t4\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:2001205\tBP\te\tnegative regulation of osteoclast development\t39/40\t39/263\t6.63e-46\t10\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1903706\tBP\te\tregulation of hemopoiesis     \t39/40\t39/263\t6.63e-46\t5\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0045638\tBP\te\tnegative regulation of myeloid cell differentiation\t39/40\t39/263\t6.63e-46\t7\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0033690\tBP\te\tpositive regulation of osteoblast proliferation\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1903555\tBP\te\tregulation of tumor necrosis factor superfamily cytokine production\t39/40\t39/263\t6.63e-46\t5\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0045671\tBP\te\tnegative regulation of osteoclast differentiation\t39/40\t39/263\t6.63e-46\t9\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0070169\tBP\te\tpositive regulation of biomineral tissue development\t39/40\t39/263\t6.63e-46\t6\t39\t5.17e-45\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0006952\tBP\te\tdefense response              \t39/40\t40/263\t2.64e-44\t3\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0019730\tBP\te\tantimicrobial humoral response\t39/40\t40/263\t2.64e-44\t5\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0002251\tBP\te\torgan or tissue specific immune response\t39/40\t40/263\t2.64e-44\t3\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0060548\tBP\te\tnegative regulation of cell death\t39/40\t40/263\t2.64e-44\t5\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0010941\tBP\te\tregulation of cell death      \t39/40\t40/263\t2.64e-44\t4\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0043067\tBP\te\tregulation of programmed cell death\t39/40\t40/263\t2.64e-44\t5\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0048585\tBP\te\tnegative regulation of response to stimulus\t39/40\t40/263\t2.64e-44\t4\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:2000116\tBP\te\tregulation of cysteine-type endopeptidase activity\t39/40\t40/263\t2.64e-44\t9\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0006959\tBP\te\thumoral immune response       \t39/40\t40/263\t2.64e-44\t3\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0009887\tBP\te\tanimal organ morphogenesis    \t39/40\t40/263\t2.64e-44\t3\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0019731\tBP\te\tantibacterial humoral response\t39/40\t40/263\t2.64e-44\t7\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0031324\tBP\te\tnegative regulation of cellular metabolic process\t39/40\t40/263\t2.64e-44\t5\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0032269\tBP\te\tnegative regulation of cellular protein metabolic process\t39/40\t40/263\t2.64e-44\t7\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0002376\tBP\te\timmune system process         \t39/40\t40/263\t2.64e-44\t1\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0052547\tBP\te\tregulation of peptidase activity\t39/40\t40/263\t2.64e-44\t7\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0052548\tBP\te\tregulation of endopeptidase activity\t39/40\t40/263\t2.64e-44\t8\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0009620\tBP\te\tresponse to fungus            \t39/40\t40/263\t2.64e-44\t5\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0045087\tBP\te\tinnate immune response        \t39/40\t40/263\t2.64e-44\t4\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051094\tBP\te\tpositive regulation of developmental process\t39/40\t40/263\t2.64e-44\t4\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0050832\tBP\te\tdefense response to fungus    \t39/40\t40/263\t2.64e-44\t6\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0023057\tBP\te\tnegative regulation of signaling\t39/40\t40/263\t2.64e-44\t4\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:2000117\tBP\te\tnegative regulation of cysteine-type endopeptidase activity\t39/40\t40/263\t2.64e-44\t11\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0002227\tBP\te\tinnate immune response in mucosa\t39/40\t40/263\t2.64e-44\t5\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051239\tBP\te\tregulation of multicellular organismal process\t39/40\t40/263\t2.64e-44\t3\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051346\tBP\te\tnegative regulation of hydrolase activity\t39/40\t40/263\t2.64e-44\t5\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0006955\tBP\te\timmune response               \t39/40\t40/263\t2.64e-44\t2\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:2000026\tBP\te\tregulation of multicellular organismal development\t39/40\t40/263\t2.64e-44\t4\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0098542\tBP\te\tdefense response to other organism\t39/40\t40/263\t2.64e-44\t5\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0009892\tBP\te\tnegative regulation of metabolic process\t39/40\t40/263\t2.64e-44\t4\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0010648\tBP\te\tnegative regulation of cell communication\t39/40\t40/263\t2.64e-44\t5\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051336\tBP\te\tregulation of hydrolase activity\t39/40\t40/263\t2.64e-44\t4\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0045597\tBP\te\tpositive regulation of cell differentiation\t39/40\t40/263\t2.64e-44\t5\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0006508\tBP\te\tproteolysis                   \t39/40\t40/263\t2.64e-44\t5\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0042742\tBP\te\tdefense response to bacterium \t39/40\t40/263\t2.64e-44\t6\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0010466\tBP\te\tnegative regulation of peptidase activity\t39/40\t40/263\t2.64e-44\t9\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0002385\tBP\te\tmucosal immune response       \t39/40\t40/263\t2.64e-44\t4\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0043069\tBP\te\tnegative regulation of programmed cell death\t39/40\t40/263\t2.64e-44\t6\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0019732\tBP\te\tantifungal humoral response   \t39/40\t40/263\t2.64e-44\t7\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0009968\tBP\te\tnegative regulation of signal transduction\t39/40\t40/263\t2.64e-44\t6\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0045861\tBP\te\tnegative regulation of proteolysis\t39/40\t40/263\t2.64e-44\t8\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0042981\tBP\te\tregulation of apoptotic process\t39/40\t40/263\t2.64e-44\t6\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0010951\tBP\te\tnegative regulation of endopeptidase activity\t39/40\t40/263\t2.64e-44\t10\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051248\tBP\te\tnegative regulation of protein metabolic process\t39/40\t40/263\t2.64e-44\t6\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0043066\tBP\te\tnegative regulation of apoptotic process\t39/40\t40/263\t2.64e-44\t7\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0009653\tBP\te\tanatomical structure morphogenesis\t39/40\t40/263\t2.64e-44\t2\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051240\tBP\te\tpositive regulation of multicellular organismal process\t39/40\t40/263\t2.64e-44\t4\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0010605\tBP\te\tnegative regulation of macromolecule metabolic process\t39/40\t40/263\t2.64e-44\t5\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051172\tBP\te\tnegative regulation of nitrogen compound metabolic process\t39/40\t40/263\t2.64e-44\t5\t39\t1.09e-43\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0032502\tBP\te\tdevelopmental process         \t39/40\t41/263\t5.39e-43\t1\t39\t2.06e-42\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0010646\tBP\te\tregulation of cell communication\t39/40\t41/263\t5.39e-43\t4\t39\t2.06e-42\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0048583\tBP\te\tregulation of response to stimulus\t39/40\t41/263\t5.39e-43\t3\t39\t2.06e-42\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0009966\tBP\te\tregulation of signal transduction\t39/40\t41/263\t5.39e-43\t5\t39\t2.06e-42\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0006950\tBP\te\tresponse to stress            \t39/40\t41/263\t5.39e-43\t2\t39\t2.06e-42\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0008284\tBP\te\tpositive regulation of cell population proliferation\t39/40\t41/263\t5.39e-43\t5\t39\t2.06e-42\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0042127\tBP\te\tregulation of cell population proliferation\t39/40\t41/263\t5.39e-43\t4\t39\t2.06e-42\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0023051\tBP\te\tregulation of signaling       \t39/40\t41/263\t5.39e-43\t3\t39\t2.06e-42\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0009605\tBP\te\tresponse to external stimulus \t39/40\t49/263\t5.21e-36\t2\t39\t1.89e-35\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0043207\tBP\te\tresponse to external biotic stimulus\t39/40\t49/263\t5.21e-36\t3\t39\t1.89e-35\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0009607\tBP\te\tresponse to biotic stimulus   \t39/40\t49/263\t5.21e-36\t2\t39\t1.89e-35\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051707\tBP\te\tresponse to other organism    \t39/40\t49/263\t5.21e-36\t4\t39\t1.89e-35\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0009617\tBP\te\tresponse to bacterium         \t39/40\t49/263\t5.21e-36\t5\t39\t1.89e-35\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051704\tBP\te\tmulti-organism process        \t39/40\t49/263\t5.21e-36\t1\t39\t1.89e-35\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0019538\tBP\te\tprotein metabolic process     \t39/40\t50/263\t2.36e-35\t4\t39\t8.14e-35\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0043170\tBP\te\tmacromolecule metabolic process\t39/40\t50/263\t2.36e-35\t3\t39\t8.14e-35\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:1901564\tBP\te\torganonitrogen compound metabolic process\t39/40\t50/263\t2.36e-35\t3\t39\t8.14e-35\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0071704\tBP\te\torganic substance metabolic process\t39/40\t50/263\t2.36e-35\t2\t39\t8.14e-35\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0006807\tBP\te\tnitrogen compound metabolic process\t39/40\t50/263\t2.36e-35\t2\t39\t8.14e-35\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0044238\tBP\te\tprimary metabolic process     \t39/40\t50/263\t2.36e-35\t2\t39\t8.14e-35\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0008152\tBP\te\tmetabolic process             \t39/40\t51/263\t9.98e-35\t1\t39\t3.41e-34\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0044092\tBP\te\tnegative regulation of molecular function\t39/40\t60/263\t4.81e-30\t3\t39\t1.62e-29\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0043086\tBP\te\tnegative regulation of catalytic activity\t39/40\t60/263\t4.81e-30\t4\t39\t1.62e-29\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0065009\tBP\te\tregulation of molecular function\t39/40\t61/263\t1.33e-29\t2\t39\t4.4e-29\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0050790\tBP\te\tregulation of catalytic activity\t39/40\t61/263\t1.33e-29\t3\t39\t4.4e-29\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0050896\tBP\te\tresponse to stimulus          \t39/40\t65/263\t5.89e-28\t1\t39\t1.94e-27\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0010721\tBP\te\tnegative regulation of cell development\t39/40\t66/263\t1.43e-27\t6\t39\t4.68e-27\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051093\tBP\te\tnegative regulation of developmental process\t39/40\t67/263\t3.41e-27\t4\t39\t1.06e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0030162\tBP\te\tregulation of proteolysis     \t39/40\t67/263\t3.41e-27\t6\t39\t1.06e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0060284\tBP\te\tregulation of cell development\t39/40\t67/263\t3.41e-27\t5\t39\t1.06e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0048523\tBP\te\tnegative regulation of cellular process\t39/40\t67/263\t3.41e-27\t4\t39\t1.06e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0045596\tBP\te\tnegative regulation of cell differentiation\t39/40\t67/263\t3.41e-27\t5\t39\t1.06e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0048519\tBP\te\tnegative regulation of biological process\t39/40\t67/263\t3.41e-27\t3\t39\t1.06e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0060255\tBP\te\tregulation of macromolecule metabolic process\t39/40\t68/263\t7.97e-27\t4\t39\t2.33e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0032268\tBP\te\tregulation of cellular protein metabolic process\t39/40\t68/263\t7.97e-27\t6\t39\t2.33e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0031323\tBP\te\tregulation of cellular metabolic process\t39/40\t68/263\t7.97e-27\t4\t39\t2.33e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0050793\tBP\te\tregulation of developmental process\t39/40\t68/263\t7.97e-27\t3\t39\t2.33e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0080090\tBP\te\tregulation of primary metabolic process\t39/40\t68/263\t7.97e-27\t4\t39\t2.33e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051246\tBP\te\tregulation of protein metabolic process\t39/40\t68/263\t7.97e-27\t5\t39\t2.33e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0045595\tBP\te\tregulation of cell differentiation\t39/40\t68/263\t7.97e-27\t4\t39\t2.33e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051171\tBP\te\tregulation of nitrogen compound metabolic process\t39/40\t68/263\t7.97e-27\t4\t39\t2.33e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0019222\tBP\te\tregulation of metabolic process\t39/40\t68/263\t7.97e-27\t3\t39\t2.33e-26\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0048518\tBP\te\tpositive regulation of biological process\t39/40\t82/263\t2.08e-22\t3\t39\t5.91e-22\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0050789\tBP\te\tregulation of biological process\t39/40\t82/263\t2.08e-22\t2\t39\t5.91e-22\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0050794\tBP\te\tregulation of cellular process\t39/40\t82/263\t2.08e-22\t3\t39\t5.91e-22\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0048522\tBP\te\tpositive regulation of cellular process\t39/40\t82/263\t2.08e-22\t4\t39\t5.91e-22\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0031640\tBP\te\tkilling of cells of other organism\t20/40\t20/263\t2.81e-19\t5\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0050778\tBP\te\tpositive regulation of immune response\t20/40\t20/263\t2.81e-19\t5\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0031349\tBP\te\tpositive regulation of defense response\t20/40\t20/263\t2.81e-19\t6\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:1903900\tBP\te\tregulation of viral life cycle\t20/40\t20/263\t2.81e-19\t6\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0034121\tBP\te\tregulation of toll-like receptor signaling pathway\t20/40\t20/263\t2.81e-19\t7\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:1903901\tBP\te\tnegative regulation of viral life cycle\t20/40\t20/263\t2.81e-19\t7\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0050829\tBP\te\tdefense response to Gram-negative bacterium\t20/40\t20/263\t2.81e-19\t7\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0045088\tBP\te\tregulation of innate immune response\t20/40\t20/263\t2.81e-19\t6\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051092\tBP\te\tpositive regulation of NF-kappaB transcription factor activity\t20/40\t20/263\t2.81e-19\t12\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0034143\tBP\te\tregulation of toll-like receptor 4 signaling pathway\t20/40\t20/263\t2.81e-19\t8\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051673\tBP\te\tmembrane disruption in other organism\t20/40\t20/263\t2.81e-19\t4\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0043122\tBP\te\tregulation of I-kappaB kinase/NF-kappaB signaling\t20/40\t20/263\t2.81e-19\t7\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0043462\tBP\te\tregulation of ATPase activity \t20/40\t20/263\t2.81e-19\t5\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0043123\tBP\te\tpositive regulation of I-kappaB kinase/NF-kappaB signaling\t20/40\t20/263\t2.81e-19\t8\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0045069\tBP\te\tregulation of viral genome replication\t20/40\t20/263\t2.81e-19\t7\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0031347\tBP\te\tregulation of defense response\t20/40\t20/263\t2.81e-19\t5\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0061844\tBP\te\tantimicrobial humoral immune response mediated by antimicrobial peptide\t20/40\t20/263\t2.81e-19\t6\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0050792\tBP\te\tregulation of viral process   \t20/40\t20/263\t2.81e-19\t5\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0001906\tBP\te\tcell killing                  \t20/40\t20/263\t2.81e-19\t1\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0034145\tBP\te\tpositive regulation of toll-like receptor 4 signaling pathway\t20/40\t20/263\t2.81e-19\t9\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0034123\tBP\te\tpositive regulation of toll-like receptor signaling pathway\t20/40\t20/263\t2.81e-19\t8\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051090\tBP\te\tregulation of DNA-binding transcription factor activity\t20/40\t20/263\t2.81e-19\t10\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051817\tBP\te\tmodification of morphology or physiology of other organism involved in symbiotic interaction\t20/40\t20/263\t2.81e-19\t4\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051702\tBP\te\tinteraction with symbiont     \t20/40\t20/263\t2.81e-19\t3\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0044793\tBP\te\tnegative regulation by host of viral process\t20/40\t20/263\t2.81e-19\t7\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0032780\tBP\te\tnegative regulation of ATPase activity\t20/40\t20/263\t2.81e-19\t6\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0050776\tBP\te\tregulation of immune response \t20/40\t20/263\t2.81e-19\t4\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051851\tBP\te\tmodification by host of symbiont morphology or physiology\t20/40\t20/263\t2.81e-19\t5\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0044364\tBP\te\tdisruption of cells of other organism\t20/40\t20/263\t2.81e-19\t4\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0044419\tBP\te\tinterspecies interaction between organisms\t20/40\t20/263\t2.81e-19\t2\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0048525\tBP\te\tnegative regulation of viral process\t20/40\t20/263\t2.81e-19\t6\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0002684\tBP\te\tpositive regulation of immune system process\t20/40\t20/263\t2.81e-19\t4\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0045071\tBP\te\tnegative regulation of viral genome replication\t20/40\t20/263\t2.81e-19\t8\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051091\tBP\te\tpositive regulation of DNA-binding transcription factor activity\t20/40\t20/263\t2.81e-19\t11\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0044788\tBP\te\tmodulation by host of viral process\t20/40\t20/263\t2.81e-19\t6\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0045089\tBP\te\tpositive regulation of innate immune response\t20/40\t20/263\t2.81e-19\t7\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0035821\tBP\te\tmodification of morphology or physiology of other organism\t20/40\t20/263\t2.81e-19\t3\t20\t6.39e-19\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051347\tBP\te\tpositive regulation of transferase activity\t20/40\t21/263\t5.43e-18\t5\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0044093\tBP\te\tpositive regulation of molecular function\t20/40\t21/263\t5.43e-18\t3\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0009889\tBP\te\tregulation of biosynthetic process\t20/40\t21/263\t5.43e-18\t4\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0023056\tBP\te\tpositive regulation of signaling\t20/40\t21/263\t5.43e-18\t4\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0042325\tBP\te\tregulation of phosphorylation \t20/40\t21/263\t5.43e-18\t7\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0043549\tBP\te\tregulation of kinase activity \t20/40\t21/263\t5.43e-18\t8\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:1902531\tBP\te\tregulation of intracellular signal transduction\t20/40\t21/263\t5.43e-18\t6\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:2000112\tBP\te\tregulation of cellular macromolecule biosynthetic process\t20/40\t21/263\t5.43e-18\t6\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0048584\tBP\te\tpositive regulation of response to stimulus\t20/40\t21/263\t5.43e-18\t4\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0045859\tBP\te\tregulation of protein kinase activity\t20/40\t21/263\t5.43e-18\t9\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0031326\tBP\te\tregulation of cellular biosynthetic process\t20/40\t21/263\t5.43e-18\t5\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0010556\tBP\te\tregulation of macromolecule biosynthetic process\t20/40\t21/263\t5.43e-18\t5\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0045937\tBP\te\tpositive regulation of phosphate metabolic process\t20/40\t21/263\t5.43e-18\t7\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0019220\tBP\te\tregulation of phosphate metabolic process\t20/40\t21/263\t5.43e-18\t6\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0009967\tBP\te\tpositive regulation of signal transduction\t20/40\t21/263\t5.43e-18\t6\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0071900\tBP\te\tregulation of protein serine/threonine kinase activity\t20/40\t21/263\t5.43e-18\t10\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051174\tBP\te\tregulation of phosphorus metabolic process\t20/40\t21/263\t5.43e-18\t5\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051252\tBP\te\tregulation of RNA metabolic process\t20/40\t21/263\t5.43e-18\t6\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0071902\tBP\te\tpositive regulation of protein serine/threonine kinase activity\t20/40\t21/263\t5.43e-18\t11\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0010562\tBP\te\tpositive regulation of phosphorus metabolic process\t20/40\t21/263\t5.43e-18\t6\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0001932\tBP\te\tregulation of protein phosphorylation\t20/40\t21/263\t5.43e-18\t8\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0033674\tBP\te\tpositive regulation of kinase activity\t20/40\t21/263\t5.43e-18\t9\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:1902533\tBP\te\tpositive regulation of intracellular signal transduction\t20/40\t21/263\t5.43e-18\t7\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0031401\tBP\te\tpositive regulation of protein modification process\t20/40\t21/263\t5.43e-18\t8\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:1903506\tBP\te\tregulation of nucleic acid-templated transcription\t20/40\t21/263\t5.43e-18\t8\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0045860\tBP\te\tpositive regulation of protein kinase activity\t20/40\t21/263\t5.43e-18\t10\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0019219\tBP\te\tregulation of nucleobase-containing compound metabolic process\t20/40\t21/263\t5.43e-18\t5\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0080134\tBP\te\tregulation of response to stress\t20/40\t21/263\t5.43e-18\t4\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0043085\tBP\te\tpositive regulation of catalytic activity\t20/40\t21/263\t5.43e-18\t4\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051338\tBP\te\tregulation of transferase activity\t20/40\t21/263\t5.43e-18\t4\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0042327\tBP\te\tpositive regulation of phosphorylation\t20/40\t21/263\t5.43e-18\t8\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0031399\tBP\te\tregulation of protein modification process\t20/40\t21/263\t5.43e-18\t7\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0006355\tBP\te\tregulation of transcription, DNA-templated\t20/40\t21/263\t5.43e-18\t9\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:2001141\tBP\te\tregulation of RNA biosynthetic process\t20/40\t21/263\t5.43e-18\t7\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0010647\tBP\te\tpositive regulation of cell communication\t20/40\t21/263\t5.43e-18\t5\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0001934\tBP\te\tpositive regulation of protein phosphorylation\t20/40\t21/263\t5.43e-18\t9\t20\t1.03e-17\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0010604\tBP\te\tpositive regulation of macromolecule metabolic process\t20/40\t48/263\t4.21e-07\t5\t20\t7.63e-07\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0031325\tBP\te\tpositive regulation of cellular metabolic process\t20/40\t48/263\t4.21e-07\t5\t20\t7.63e-07\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051173\tBP\te\tpositive regulation of nitrogen compound metabolic process\t20/40\t48/263\t4.21e-07\t5\t20\t7.63e-07\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0010468\tBP\te\tregulation of gene expression \t20/40\t48/263\t4.21e-07\t5\t20\t7.63e-07\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051247\tBP\te\tpositive regulation of protein metabolic process\t20/40\t48/263\t4.21e-07\t6\t20\t7.63e-07\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0009893\tBP\te\tpositive regulation of metabolic process\t20/40\t48/263\t4.21e-07\t4\t20\t7.63e-07\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0032270\tBP\te\tpositive regulation of cellular protein metabolic process\t20/40\t48/263\t4.21e-07\t7\t20\t7.63e-07\tAILME19349, BOVIN10421, CHLSB10290, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MOUSE53077, MUSPF09885, MYOLU10560, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, RABIT12763, RATNO20342, SHEEP08528\n",
      "GO:0051234\tBP\te\testablishment of localization \t39/40\t207/263\t0.000605\t2\t39\t0.00101\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0050801\tBP\te\tion homeostasis               \t39/40\t207/263\t0.000605\t5\t39\t0.00101\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0055072\tBP\te\tiron ion homeostasis          \t39/40\t207/263\t0.000605\t9\t39\t0.00101\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0055080\tBP\te\tcation homeostasis            \t39/40\t207/263\t0.000605\t6\t39\t0.00101\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0051179\tBP\te\tlocalization                  \t39/40\t207/263\t0.000605\t1\t39\t0.00101\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0098771\tBP\te\tinorganic ion homeostasis     \t39/40\t207/263\t0.000605\t6\t39\t0.00101\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0055076\tBP\te\ttransition metal ion homeostasis\t39/40\t207/263\t0.000605\t8\t39\t0.00101\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0065008\tBP\te\tregulation of biological quality\t39/40\t207/263\t0.000605\t2\t39\t0.00101\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0006811\tBP\te\tion transport                 \t39/40\t207/263\t0.000605\t4\t39\t0.00101\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0048878\tBP\te\tchemical homeostasis          \t39/40\t207/263\t0.000605\t4\t39\t0.00101\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0055065\tBP\te\tmetal ion homeostasis         \t39/40\t207/263\t0.000605\t7\t39\t0.00101\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0042592\tBP\te\thomeostatic process           \t39/40\t207/263\t0.000605\t3\t39\t0.00101\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0006810\tBP\te\ttransport                     \t39/40\t207/263\t0.000605\t3\t39\t0.00101\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0065007\tBP\te\tbiological regulation         \t39/40\t227/263\t0.0234\t1\t39\t0.0351\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0008150\tBP\te\tbiological_process            \t39/40\t227/263\t0.0234\t0\t39\t0.0351\tAILME19349, BOVIN10421, CALJA07214, CANLF07574, CAVPO15803, CHILA06139, CHLSB10290, DASNO15901, FELCA01815, FUKDA00881, GORGO13640, HORSE06788, HUMAN20795, ICTTR00008, LOXAF14821, MACMU13343, MICMU05125, MOUSE53077, MUSPF09885, MYOLU10560, NANGA19399, NOMLE02731, OCHPR01366, OCTDE19528, OTOGA08096, PANPA27700, PANTR30966, PAPAN10531, PIGXX03930, PONAB10845, PROCA07246, PTEVA02104, RABIT12763, RATNO20342, SHEEP08528, SORAR11450, TARSY07060, TURTR11384, VICPA07246\n",
      "GO:0006826\tBP\tp\tiron ion transport            \t0/40\t86/263\t4.76e-08\t8\t0\t8.9e-08\t               \n",
      "GO:0006812\tBP\tp\tcation transport              \t0/40\t86/263\t4.76e-08\t5\t0\t8.9e-08\t               \n",
      "GO:0030001\tBP\tp\tmetal ion transport           \t0/40\t86/263\t4.76e-08\t6\t0\t8.9e-08\t               \n",
      "GO:0000041\tBP\tp\ttransition metal ion transport\t0/40\t86/263\t4.76e-08\t7\t0\t8.9e-08\t               \n",
      "GO:0009987\tBP\tp\tcellular process              \t1/40\t70/263\t3.01e-05\t1\t1\t5.44e-05\t     HUMAN20795\n",
      "GO:0055082\tBP\tp\tcellular chemical homeostasis \t0/40\t58/263\t3.65e-05\t5\t0\t6.4e-05\t               \n",
      "GO:0006879\tBP\tp\tcellular iron ion homeostasis \t0/40\t58/263\t3.65e-05\t10\t0\t6.4e-05\t               \n",
      "GO:0030003\tBP\tp\tcellular cation homeostasis   \t0/40\t58/263\t3.65e-05\t7\t0\t6.4e-05\t               \n",
      "GO:0006875\tBP\tp\tcellular metal ion homeostasis\t0/40\t58/263\t3.65e-05\t8\t0\t6.4e-05\t               \n",
      "GO:0019725\tBP\tp\tcellular homeostasis          \t0/40\t58/263\t3.65e-05\t4\t0\t6.4e-05\t               \n",
      "GO:0046916\tBP\tp\tcellular transition metal ion homeostasis\t0/40\t58/263\t3.65e-05\t9\t0\t6.4e-05\t               \n",
      "GO:0006873\tBP\tp\tcellular ion homeostasis      \t0/40\t58/263\t3.65e-05\t6\t0\t6.4e-05\t               \n",
      "GO:0051128\tBP\tp\tregulation of cellular component organization\t0/40\t42/263\t0.000739\t4\t0\t0.00122\t               \n",
      "GO:0051130\tBP\tp\tpositive regulation of cellular component organization\t0/40\t42/263\t0.000739\t5\t0\t0.00122\t               \n",
      "GO:0010628\tBP\tp\tpositive regulation of gene expression\t0/40\t28/263\t0.0112\t6\t0\t0.0184\t               \n",
      "GO:1903053\tBP\tp\tregulation of extracellular matrix organization\t0/40\t27/263\t0.0195\t5\t0\t0.0295\t               \n",
      "GO:0022603\tBP\tp\tregulation of anatomical structure morphogenesis\t0/40\t27/263\t0.0195\t4\t0\t0.0295\t               \n",
      "GO:1900025\tBP\tp\tnegative regulation of substrate adhesion-dependent cell spreading\t0/40\t27/263\t0.0195\t8\t0\t0.0295\t               \n",
      "GO:0010810\tBP\tp\tregulation of cell-substrate adhesion\t0/40\t27/263\t0.0195\t4\t0\t0.0295\t               \n",
      "GO:0010954\tBP\tp\tpositive regulation of protein processing\t0/40\t27/263\t0.0195\t9\t0\t0.0295\t               \n",
      "GO:0090091\tBP\tp\tpositive regulation of extracellular matrix disassembly\t0/40\t27/263\t0.0195\t7\t0\t0.0295\t               \n",
      "GO:0010812\tBP\tp\tnegative regulation of cell-substrate adhesion\t0/40\t27/263\t0.0195\t6\t0\t0.0295\t               \n",
      "GO:0010715\tBP\tp\tregulation of extracellular matrix disassembly\t0/40\t27/263\t0.0195\t6\t0\t0.0295\t               \n",
      "GO:0070613\tBP\tp\tregulation of protein processing\t0/40\t27/263\t0.0195\t7\t0\t0.0295\t               \n",
      "GO:1903317\tBP\tp\tregulation of protein maturation\t0/40\t27/263\t0.0195\t6\t0\t0.0295\t               \n",
      "GO:0022604\tBP\tp\tregulation of cell morphogenesis\t0/40\t27/263\t0.0195\t5\t0\t0.0295\t               \n",
      "GO:0045862\tBP\tp\tpositive regulation of proteolysis\t0/40\t27/263\t0.0195\t8\t0\t0.0295\t               \n",
      "GO:0010756\tBP\tp\tpositive regulation of plasminogen activation\t0/40\t27/263\t0.0195\t10\t0\t0.0295\t               \n",
      "GO:0030155\tBP\tp\tregulation of cell adhesion   \t0/40\t27/263\t0.0195\t3\t0\t0.0295\t               \n",
      "GO:0010771\tBP\tp\tnegative regulation of cell morphogenesis involved in differentiation\t0/40\t27/263\t0.0195\t7\t0\t0.0295\t               \n",
      "GO:0051129\tBP\tp\tnegative regulation of cellular component organization\t0/40\t27/263\t0.0195\t5\t0\t0.0295\t               \n",
      "GO:1903055\tBP\tp\tpositive regulation of extracellular matrix organization\t0/40\t27/263\t0.0195\t6\t0\t0.0295\t               \n",
      "GO:1903319\tBP\tp\tpositive regulation of protein maturation\t0/40\t27/263\t0.0195\t7\t0\t0.0295\t               \n",
      "GO:0010769\tBP\tp\tregulation of cell morphogenesis involved in differentiation\t0/40\t27/263\t0.0195\t6\t0\t0.0295\t               \n",
      "GO:0010755\tBP\tp\tregulation of plasminogen activation\t0/40\t27/263\t0.0195\t8\t0\t0.0295\t               \n",
      "GO:1900024\tBP\tp\tregulation of substrate adhesion-dependent cell spreading\t0/40\t27/263\t0.0195\t7\t0\t0.0295\t               \n",
      "GO:0007162\tBP\tp\tnegative regulation of cell adhesion\t0/40\t27/263\t0.0195\t5\t0\t0.0295\t               \n"
     ]
    }
   ],
   "source": [
    "goea.print_results(results)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "It's also possible to convert this into a data frame, for further analysis. However, there's currently no built-in support for this in GOATOOLS."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 26,
   "metadata": {},
   "outputs": [],
   "source": [
    "import pandas as pd\n",
    "res = pd.DataFrame.from_records((dict(zip(z.get_prtflds_default(), \n",
    "                                          z.get_field_values(z.get_prtflds_default()))) \n",
    "                                 for z in goea.get_adj_records(results)))"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 27,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>GO</th>\n",
       "      <th>NS</th>\n",
       "      <th>depth</th>\n",
       "      <th>enrichment</th>\n",
       "      <th>name</th>\n",
       "      <th>p_fdr_bh</th>\n",
       "      <th>p_uncorrected</th>\n",
       "      <th>ratio_in_pop</th>\n",
       "      <th>ratio_in_study</th>\n",
       "      <th>study_count</th>\n",
       "      <th>study_items</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>GO:1900228</td>\n",
       "      <td>BP</td>\n",
       "      <td>5</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of single-species biofilm formation...</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>GO:0043900</td>\n",
       "      <td>BP</td>\n",
       "      <td>3</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of multi-organism process</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>GO:0032101</td>\n",
       "      <td>BP</td>\n",
       "      <td>4</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of response to external stimulus</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>GO:1903011</td>\n",
       "      <td>BP</td>\n",
       "      <td>6</td>\n",
       "      <td>e</td>\n",
       "      <td>negative regulation of bone development</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>GO:0002682</td>\n",
       "      <td>BP</td>\n",
       "      <td>3</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of immune system process</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5</th>\n",
       "      <td>GO:0030501</td>\n",
       "      <td>BP</td>\n",
       "      <td>7</td>\n",
       "      <td>e</td>\n",
       "      <td>positive regulation of bone mineralization</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6</th>\n",
       "      <td>GO:1902105</td>\n",
       "      <td>BP</td>\n",
       "      <td>6</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of leukocyte differentiation</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7</th>\n",
       "      <td>GO:0002831</td>\n",
       "      <td>BP</td>\n",
       "      <td>4</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of response to biotic stimulus</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>8</th>\n",
       "      <td>GO:1900157</td>\n",
       "      <td>BP</td>\n",
       "      <td>7</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of bone mineralization involved in ...</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>9</th>\n",
       "      <td>GO:0043903</td>\n",
       "      <td>BP</td>\n",
       "      <td>4</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of symbiosis, encompassing mutualis...</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>GO:0002832</td>\n",
       "      <td>BP</td>\n",
       "      <td>5</td>\n",
       "      <td>e</td>\n",
       "      <td>negative regulation of response to biotic stim...</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11</th>\n",
       "      <td>GO:1903012</td>\n",
       "      <td>BP</td>\n",
       "      <td>6</td>\n",
       "      <td>e</td>\n",
       "      <td>positive regulation of bone development</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12</th>\n",
       "      <td>GO:0045667</td>\n",
       "      <td>BP</td>\n",
       "      <td>5</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of osteoblast differentiation</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13</th>\n",
       "      <td>GO:0045670</td>\n",
       "      <td>BP</td>\n",
       "      <td>8</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of osteoclast differentiation</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14</th>\n",
       "      <td>GO:0031665</td>\n",
       "      <td>BP</td>\n",
       "      <td>7</td>\n",
       "      <td>e</td>\n",
       "      <td>negative regulation of lipopolysaccharide-medi...</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15</th>\n",
       "      <td>GO:1903010</td>\n",
       "      <td>BP</td>\n",
       "      <td>5</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of bone development</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16</th>\n",
       "      <td>GO:2001204</td>\n",
       "      <td>BP</td>\n",
       "      <td>9</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of osteoclast development</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17</th>\n",
       "      <td>GO:0032102</td>\n",
       "      <td>BP</td>\n",
       "      <td>5</td>\n",
       "      <td>e</td>\n",
       "      <td>negative regulation of response to external st...</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18</th>\n",
       "      <td>GO:0032501</td>\n",
       "      <td>BP</td>\n",
       "      <td>1</td>\n",
       "      <td>e</td>\n",
       "      <td>multicellular organismal process</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19</th>\n",
       "      <td>GO:0030278</td>\n",
       "      <td>BP</td>\n",
       "      <td>4</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of ossification</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>20</th>\n",
       "      <td>GO:0060349</td>\n",
       "      <td>BP</td>\n",
       "      <td>4</td>\n",
       "      <td>e</td>\n",
       "      <td>bone morphogenesis</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21</th>\n",
       "      <td>GO:0070167</td>\n",
       "      <td>BP</td>\n",
       "      <td>5</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of biomineral tissue development</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>22</th>\n",
       "      <td>GO:0001818</td>\n",
       "      <td>BP</td>\n",
       "      <td>5</td>\n",
       "      <td>e</td>\n",
       "      <td>negative regulation of cytokine production</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23</th>\n",
       "      <td>GO:0032680</td>\n",
       "      <td>BP</td>\n",
       "      <td>6</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of tumor necrosis factor production</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24</th>\n",
       "      <td>GO:0001817</td>\n",
       "      <td>BP</td>\n",
       "      <td>4</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of cytokine production</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>25</th>\n",
       "      <td>GO:0002683</td>\n",
       "      <td>BP</td>\n",
       "      <td>4</td>\n",
       "      <td>e</td>\n",
       "      <td>negative regulation of immune system process</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26</th>\n",
       "      <td>GO:0045669</td>\n",
       "      <td>BP</td>\n",
       "      <td>6</td>\n",
       "      <td>e</td>\n",
       "      <td>positive regulation of osteoblast differentiation</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>27</th>\n",
       "      <td>GO:0001503</td>\n",
       "      <td>BP</td>\n",
       "      <td>2</td>\n",
       "      <td>e</td>\n",
       "      <td>ossification</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>28</th>\n",
       "      <td>GO:0045778</td>\n",
       "      <td>BP</td>\n",
       "      <td>5</td>\n",
       "      <td>e</td>\n",
       "      <td>positive regulation of ossification</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>29</th>\n",
       "      <td>GO:0031664</td>\n",
       "      <td>BP</td>\n",
       "      <td>6</td>\n",
       "      <td>e</td>\n",
       "      <td>regulation of lipopolysaccharide-mediated sign...</td>\n",
       "      <td>5.168715e-45</td>\n",
       "      <td>6.629705e-46</td>\n",
       "      <td>39/263</td>\n",
       "      <td>39/40</td>\n",
       "      <td>39</td>\n",
       "      <td>AILME19349, BOVIN10421, CALJA07214, CANLF07574...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>...</th>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "      <td>...</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>250</th>\n",
       "      <td>GO:0030003</td>\n",
       "      <td>BP</td>\n",
       "      <td>7</td>\n",
       "      <td>p</td>\n",
       "      <td>cellular cation homeostasis</td>\n",
       "      <td>6.395619e-05</td>\n",
       "      <td>3.645958e-05</td>\n",
       "      <td>58/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>251</th>\n",
       "      <td>GO:0006875</td>\n",
       "      <td>BP</td>\n",
       "      <td>8</td>\n",
       "      <td>p</td>\n",
       "      <td>cellular metal ion homeostasis</td>\n",
       "      <td>6.395619e-05</td>\n",
       "      <td>3.645958e-05</td>\n",
       "      <td>58/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>252</th>\n",
       "      <td>GO:0019725</td>\n",
       "      <td>BP</td>\n",
       "      <td>4</td>\n",
       "      <td>p</td>\n",
       "      <td>cellular homeostasis</td>\n",
       "      <td>6.395619e-05</td>\n",
       "      <td>3.645958e-05</td>\n",
       "      <td>58/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>253</th>\n",
       "      <td>GO:0046916</td>\n",
       "      <td>BP</td>\n",
       "      <td>9</td>\n",
       "      <td>p</td>\n",
       "      <td>cellular transition metal ion homeostasis</td>\n",
       "      <td>6.395619e-05</td>\n",
       "      <td>3.645958e-05</td>\n",
       "      <td>58/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>254</th>\n",
       "      <td>GO:0006873</td>\n",
       "      <td>BP</td>\n",
       "      <td>6</td>\n",
       "      <td>p</td>\n",
       "      <td>cellular ion homeostasis</td>\n",
       "      <td>6.395619e-05</td>\n",
       "      <td>3.645958e-05</td>\n",
       "      <td>58/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>255</th>\n",
       "      <td>GO:0051128</td>\n",
       "      <td>BP</td>\n",
       "      <td>4</td>\n",
       "      <td>p</td>\n",
       "      <td>regulation of cellular component organization</td>\n",
       "      <td>1.220805e-03</td>\n",
       "      <td>7.394423e-04</td>\n",
       "      <td>42/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>256</th>\n",
       "      <td>GO:0051130</td>\n",
       "      <td>BP</td>\n",
       "      <td>5</td>\n",
       "      <td>p</td>\n",
       "      <td>positive regulation of cellular component orga...</td>\n",
       "      <td>1.220805e-03</td>\n",
       "      <td>7.394423e-04</td>\n",
       "      <td>42/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>257</th>\n",
       "      <td>GO:0010628</td>\n",
       "      <td>BP</td>\n",
       "      <td>6</td>\n",
       "      <td>p</td>\n",
       "      <td>positive regulation of gene expression</td>\n",
       "      <td>1.837141e-02</td>\n",
       "      <td>1.117121e-02</td>\n",
       "      <td>28/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>258</th>\n",
       "      <td>GO:1903053</td>\n",
       "      <td>BP</td>\n",
       "      <td>5</td>\n",
       "      <td>p</td>\n",
       "      <td>regulation of extracellular matrix organization</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>259</th>\n",
       "      <td>GO:0022603</td>\n",
       "      <td>BP</td>\n",
       "      <td>4</td>\n",
       "      <td>p</td>\n",
       "      <td>regulation of anatomical structure morphogenesis</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>260</th>\n",
       "      <td>GO:1900025</td>\n",
       "      <td>BP</td>\n",
       "      <td>8</td>\n",
       "      <td>p</td>\n",
       "      <td>negative regulation of substrate adhesion-depe...</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>261</th>\n",
       "      <td>GO:0010810</td>\n",
       "      <td>BP</td>\n",
       "      <td>4</td>\n",
       "      <td>p</td>\n",
       "      <td>regulation of cell-substrate adhesion</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>262</th>\n",
       "      <td>GO:0010954</td>\n",
       "      <td>BP</td>\n",
       "      <td>9</td>\n",
       "      <td>p</td>\n",
       "      <td>positive regulation of protein processing</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>263</th>\n",
       "      <td>GO:0090091</td>\n",
       "      <td>BP</td>\n",
       "      <td>7</td>\n",
       "      <td>p</td>\n",
       "      <td>positive regulation of extracellular matrix di...</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>264</th>\n",
       "      <td>GO:0010812</td>\n",
       "      <td>BP</td>\n",
       "      <td>6</td>\n",
       "      <td>p</td>\n",
       "      <td>negative regulation of cell-substrate adhesion</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>265</th>\n",
       "      <td>GO:0010715</td>\n",
       "      <td>BP</td>\n",
       "      <td>6</td>\n",
       "      <td>p</td>\n",
       "      <td>regulation of extracellular matrix disassembly</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>266</th>\n",
       "      <td>GO:0070613</td>\n",
       "      <td>BP</td>\n",
       "      <td>7</td>\n",
       "      <td>p</td>\n",
       "      <td>regulation of protein processing</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>267</th>\n",
       "      <td>GO:1903317</td>\n",
       "      <td>BP</td>\n",
       "      <td>6</td>\n",
       "      <td>p</td>\n",
       "      <td>regulation of protein maturation</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>268</th>\n",
       "      <td>GO:0022604</td>\n",
       "      <td>BP</td>\n",
       "      <td>5</td>\n",
       "      <td>p</td>\n",
       "      <td>regulation of cell morphogenesis</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>269</th>\n",
       "      <td>GO:0045862</td>\n",
       "      <td>BP</td>\n",
       "      <td>8</td>\n",
       "      <td>p</td>\n",
       "      <td>positive regulation of proteolysis</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>270</th>\n",
       "      <td>GO:0010756</td>\n",
       "      <td>BP</td>\n",
       "      <td>10</td>\n",
       "      <td>p</td>\n",
       "      <td>positive regulation of plasminogen activation</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>271</th>\n",
       "      <td>GO:0030155</td>\n",
       "      <td>BP</td>\n",
       "      <td>3</td>\n",
       "      <td>p</td>\n",
       "      <td>regulation of cell adhesion</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>272</th>\n",
       "      <td>GO:0010771</td>\n",
       "      <td>BP</td>\n",
       "      <td>7</td>\n",
       "      <td>p</td>\n",
       "      <td>negative regulation of cell morphogenesis invo...</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>273</th>\n",
       "      <td>GO:0051129</td>\n",
       "      <td>BP</td>\n",
       "      <td>5</td>\n",
       "      <td>p</td>\n",
       "      <td>negative regulation of cellular component orga...</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>274</th>\n",
       "      <td>GO:1903055</td>\n",
       "      <td>BP</td>\n",
       "      <td>6</td>\n",
       "      <td>p</td>\n",
       "      <td>positive regulation of extracellular matrix or...</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>275</th>\n",
       "      <td>GO:1903319</td>\n",
       "      <td>BP</td>\n",
       "      <td>7</td>\n",
       "      <td>p</td>\n",
       "      <td>positive regulation of protein maturation</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>276</th>\n",
       "      <td>GO:0010769</td>\n",
       "      <td>BP</td>\n",
       "      <td>6</td>\n",
       "      <td>p</td>\n",
       "      <td>regulation of cell morphogenesis involved in d...</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>277</th>\n",
       "      <td>GO:0010755</td>\n",
       "      <td>BP</td>\n",
       "      <td>8</td>\n",
       "      <td>p</td>\n",
       "      <td>regulation of plasminogen activation</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>278</th>\n",
       "      <td>GO:1900024</td>\n",
       "      <td>BP</td>\n",
       "      <td>7</td>\n",
       "      <td>p</td>\n",
       "      <td>regulation of substrate adhesion-dependent cel...</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>279</th>\n",
       "      <td>GO:0007162</td>\n",
       "      <td>BP</td>\n",
       "      <td>5</td>\n",
       "      <td>p</td>\n",
       "      <td>negative regulation of cell adhesion</td>\n",
       "      <td>2.948552e-02</td>\n",
       "      <td>1.947025e-02</td>\n",
       "      <td>27/263</td>\n",
       "      <td>0/40</td>\n",
       "      <td>0</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "<p>280 rows × 11 columns</p>\n",
       "</div>"
      ],
      "text/plain": [
       "             GO  NS  depth enrichment  \\\n",
       "0    GO:1900228  BP      5          e   \n",
       "1    GO:0043900  BP      3          e   \n",
       "2    GO:0032101  BP      4          e   \n",
       "3    GO:1903011  BP      6          e   \n",
       "4    GO:0002682  BP      3          e   \n",
       "5    GO:0030501  BP      7          e   \n",
       "6    GO:1902105  BP      6          e   \n",
       "7    GO:0002831  BP      4          e   \n",
       "8    GO:1900157  BP      7          e   \n",
       "9    GO:0043903  BP      4          e   \n",
       "10   GO:0002832  BP      5          e   \n",
       "11   GO:1903012  BP      6          e   \n",
       "12   GO:0045667  BP      5          e   \n",
       "13   GO:0045670  BP      8          e   \n",
       "14   GO:0031665  BP      7          e   \n",
       "15   GO:1903010  BP      5          e   \n",
       "16   GO:2001204  BP      9          e   \n",
       "17   GO:0032102  BP      5          e   \n",
       "18   GO:0032501  BP      1          e   \n",
       "19   GO:0030278  BP      4          e   \n",
       "20   GO:0060349  BP      4          e   \n",
       "21   GO:0070167  BP      5          e   \n",
       "22   GO:0001818  BP      5          e   \n",
       "23   GO:0032680  BP      6          e   \n",
       "24   GO:0001817  BP      4          e   \n",
       "25   GO:0002683  BP      4          e   \n",
       "26   GO:0045669  BP      6          e   \n",
       "27   GO:0001503  BP      2          e   \n",
       "28   GO:0045778  BP      5          e   \n",
       "29   GO:0031664  BP      6          e   \n",
       "..          ...  ..    ...        ...   \n",
       "250  GO:0030003  BP      7          p   \n",
       "251  GO:0006875  BP      8          p   \n",
       "252  GO:0019725  BP      4          p   \n",
       "253  GO:0046916  BP      9          p   \n",
       "254  GO:0006873  BP      6          p   \n",
       "255  GO:0051128  BP      4          p   \n",
       "256  GO:0051130  BP      5          p   \n",
       "257  GO:0010628  BP      6          p   \n",
       "258  GO:1903053  BP      5          p   \n",
       "259  GO:0022603  BP      4          p   \n",
       "260  GO:1900025  BP      8          p   \n",
       "261  GO:0010810  BP      4          p   \n",
       "262  GO:0010954  BP      9          p   \n",
       "263  GO:0090091  BP      7          p   \n",
       "264  GO:0010812  BP      6          p   \n",
       "265  GO:0010715  BP      6          p   \n",
       "266  GO:0070613  BP      7          p   \n",
       "267  GO:1903317  BP      6          p   \n",
       "268  GO:0022604  BP      5          p   \n",
       "269  GO:0045862  BP      8          p   \n",
       "270  GO:0010756  BP     10          p   \n",
       "271  GO:0030155  BP      3          p   \n",
       "272  GO:0010771  BP      7          p   \n",
       "273  GO:0051129  BP      5          p   \n",
       "274  GO:1903055  BP      6          p   \n",
       "275  GO:1903319  BP      7          p   \n",
       "276  GO:0010769  BP      6          p   \n",
       "277  GO:0010755  BP      8          p   \n",
       "278  GO:1900024  BP      7          p   \n",
       "279  GO:0007162  BP      5          p   \n",
       "\n",
       "                                                  name      p_fdr_bh  \\\n",
       "0    regulation of single-species biofilm formation...  5.168715e-45   \n",
       "1                 regulation of multi-organism process  5.168715e-45   \n",
       "2          regulation of response to external stimulus  5.168715e-45   \n",
       "3              negative regulation of bone development  5.168715e-45   \n",
       "4                  regulation of immune system process  5.168715e-45   \n",
       "5           positive regulation of bone mineralization  5.168715e-45   \n",
       "6              regulation of leukocyte differentiation  5.168715e-45   \n",
       "7            regulation of response to biotic stimulus  5.168715e-45   \n",
       "8    regulation of bone mineralization involved in ...  5.168715e-45   \n",
       "9    regulation of symbiosis, encompassing mutualis...  5.168715e-45   \n",
       "10   negative regulation of response to biotic stim...  5.168715e-45   \n",
       "11             positive regulation of bone development  5.168715e-45   \n",
       "12            regulation of osteoblast differentiation  5.168715e-45   \n",
       "13            regulation of osteoclast differentiation  5.168715e-45   \n",
       "14   negative regulation of lipopolysaccharide-medi...  5.168715e-45   \n",
       "15                      regulation of bone development  5.168715e-45   \n",
       "16                regulation of osteoclast development  5.168715e-45   \n",
       "17   negative regulation of response to external st...  5.168715e-45   \n",
       "18                    multicellular organismal process  5.168715e-45   \n",
       "19                          regulation of ossification  5.168715e-45   \n",
       "20                                  bone morphogenesis  5.168715e-45   \n",
       "21         regulation of biomineral tissue development  5.168715e-45   \n",
       "22          negative regulation of cytokine production  5.168715e-45   \n",
       "23      regulation of tumor necrosis factor production  5.168715e-45   \n",
       "24                   regulation of cytokine production  5.168715e-45   \n",
       "25        negative regulation of immune system process  5.168715e-45   \n",
       "26   positive regulation of osteoblast differentiation  5.168715e-45   \n",
       "27                                        ossification  5.168715e-45   \n",
       "28                 positive regulation of ossification  5.168715e-45   \n",
       "29   regulation of lipopolysaccharide-mediated sign...  5.168715e-45   \n",
       "..                                                 ...           ...   \n",
       "250                        cellular cation homeostasis  6.395619e-05   \n",
       "251                     cellular metal ion homeostasis  6.395619e-05   \n",
       "252                               cellular homeostasis  6.395619e-05   \n",
       "253          cellular transition metal ion homeostasis  6.395619e-05   \n",
       "254                           cellular ion homeostasis  6.395619e-05   \n",
       "255      regulation of cellular component organization  1.220805e-03   \n",
       "256  positive regulation of cellular component orga...  1.220805e-03   \n",
       "257             positive regulation of gene expression  1.837141e-02   \n",
       "258    regulation of extracellular matrix organization  2.948552e-02   \n",
       "259   regulation of anatomical structure morphogenesis  2.948552e-02   \n",
       "260  negative regulation of substrate adhesion-depe...  2.948552e-02   \n",
       "261              regulation of cell-substrate adhesion  2.948552e-02   \n",
       "262          positive regulation of protein processing  2.948552e-02   \n",
       "263  positive regulation of extracellular matrix di...  2.948552e-02   \n",
       "264     negative regulation of cell-substrate adhesion  2.948552e-02   \n",
       "265     regulation of extracellular matrix disassembly  2.948552e-02   \n",
       "266                   regulation of protein processing  2.948552e-02   \n",
       "267                   regulation of protein maturation  2.948552e-02   \n",
       "268                   regulation of cell morphogenesis  2.948552e-02   \n",
       "269                 positive regulation of proteolysis  2.948552e-02   \n",
       "270      positive regulation of plasminogen activation  2.948552e-02   \n",
       "271                        regulation of cell adhesion  2.948552e-02   \n",
       "272  negative regulation of cell morphogenesis invo...  2.948552e-02   \n",
       "273  negative regulation of cellular component orga...  2.948552e-02   \n",
       "274  positive regulation of extracellular matrix or...  2.948552e-02   \n",
       "275          positive regulation of protein maturation  2.948552e-02   \n",
       "276  regulation of cell morphogenesis involved in d...  2.948552e-02   \n",
       "277               regulation of plasminogen activation  2.948552e-02   \n",
       "278  regulation of substrate adhesion-dependent cel...  2.948552e-02   \n",
       "279               negative regulation of cell adhesion  2.948552e-02   \n",
       "\n",
       "     p_uncorrected ratio_in_pop ratio_in_study  study_count  \\\n",
       "0     6.629705e-46       39/263          39/40           39   \n",
       "1     6.629705e-46       39/263          39/40           39   \n",
       "2     6.629705e-46       39/263          39/40           39   \n",
       "3     6.629705e-46       39/263          39/40           39   \n",
       "4     6.629705e-46       39/263          39/40           39   \n",
       "5     6.629705e-46       39/263          39/40           39   \n",
       "6     6.629705e-46       39/263          39/40           39   \n",
       "7     6.629705e-46       39/263          39/40           39   \n",
       "8     6.629705e-46       39/263          39/40           39   \n",
       "9     6.629705e-46       39/263          39/40           39   \n",
       "10    6.629705e-46       39/263          39/40           39   \n",
       "11    6.629705e-46       39/263          39/40           39   \n",
       "12    6.629705e-46       39/263          39/40           39   \n",
       "13    6.629705e-46       39/263          39/40           39   \n",
       "14    6.629705e-46       39/263          39/40           39   \n",
       "15    6.629705e-46       39/263          39/40           39   \n",
       "16    6.629705e-46       39/263          39/40           39   \n",
       "17    6.629705e-46       39/263          39/40           39   \n",
       "18    6.629705e-46       39/263          39/40           39   \n",
       "19    6.629705e-46       39/263          39/40           39   \n",
       "20    6.629705e-46       39/263          39/40           39   \n",
       "21    6.629705e-46       39/263          39/40           39   \n",
       "22    6.629705e-46       39/263          39/40           39   \n",
       "23    6.629705e-46       39/263          39/40           39   \n",
       "24    6.629705e-46       39/263          39/40           39   \n",
       "25    6.629705e-46       39/263          39/40           39   \n",
       "26    6.629705e-46       39/263          39/40           39   \n",
       "27    6.629705e-46       39/263          39/40           39   \n",
       "28    6.629705e-46       39/263          39/40           39   \n",
       "29    6.629705e-46       39/263          39/40           39   \n",
       "..             ...          ...            ...          ...   \n",
       "250   3.645958e-05       58/263           0/40            0   \n",
       "251   3.645958e-05       58/263           0/40            0   \n",
       "252   3.645958e-05       58/263           0/40            0   \n",
       "253   3.645958e-05       58/263           0/40            0   \n",
       "254   3.645958e-05       58/263           0/40            0   \n",
       "255   7.394423e-04       42/263           0/40            0   \n",
       "256   7.394423e-04       42/263           0/40            0   \n",
       "257   1.117121e-02       28/263           0/40            0   \n",
       "258   1.947025e-02       27/263           0/40            0   \n",
       "259   1.947025e-02       27/263           0/40            0   \n",
       "260   1.947025e-02       27/263           0/40            0   \n",
       "261   1.947025e-02       27/263           0/40            0   \n",
       "262   1.947025e-02       27/263           0/40            0   \n",
       "263   1.947025e-02       27/263           0/40            0   \n",
       "264   1.947025e-02       27/263           0/40            0   \n",
       "265   1.947025e-02       27/263           0/40            0   \n",
       "266   1.947025e-02       27/263           0/40            0   \n",
       "267   1.947025e-02       27/263           0/40            0   \n",
       "268   1.947025e-02       27/263           0/40            0   \n",
       "269   1.947025e-02       27/263           0/40            0   \n",
       "270   1.947025e-02       27/263           0/40            0   \n",
       "271   1.947025e-02       27/263           0/40            0   \n",
       "272   1.947025e-02       27/263           0/40            0   \n",
       "273   1.947025e-02       27/263           0/40            0   \n",
       "274   1.947025e-02       27/263           0/40            0   \n",
       "275   1.947025e-02       27/263           0/40            0   \n",
       "276   1.947025e-02       27/263           0/40            0   \n",
       "277   1.947025e-02       27/263           0/40            0   \n",
       "278   1.947025e-02       27/263           0/40            0   \n",
       "279   1.947025e-02       27/263           0/40            0   \n",
       "\n",
       "                                           study_items  \n",
       "0    AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "1    AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "2    AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "3    AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "4    AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "5    AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "6    AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "7    AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "8    AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "9    AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "10   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "11   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "12   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "13   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "14   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "15   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "16   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "17   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "18   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "19   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "20   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "21   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "22   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "23   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "24   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "25   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "26   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "27   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "28   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "29   AILME19349, BOVIN10421, CALJA07214, CANLF07574...  \n",
       "..                                                 ...  \n",
       "250                                                     \n",
       "251                                                     \n",
       "252                                                     \n",
       "253                                                     \n",
       "254                                                     \n",
       "255                                                     \n",
       "256                                                     \n",
       "257                                                     \n",
       "258                                                     \n",
       "259                                                     \n",
       "260                                                     \n",
       "261                                                     \n",
       "262                                                     \n",
       "263                                                     \n",
       "264                                                     \n",
       "265                                                     \n",
       "266                                                     \n",
       "267                                                     \n",
       "268                                                     \n",
       "269                                                     \n",
       "270                                                     \n",
       "271                                                     \n",
       "272                                                     \n",
       "273                                                     \n",
       "274                                                     \n",
       "275                                                     \n",
       "276                                                     \n",
       "277                                                     \n",
       "278                                                     \n",
       "279                                                     \n",
       "\n",
       "[280 rows x 11 columns]"
      ]
     },
     "execution_count": 27,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "res"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "---"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Example 3 - Taxonomic Tree Visualisation\n",
    "Here, we look at how to load the current taxonomy in the OMA browser. Options are available to retrieve the Newick string or PhyloXML are available.\n",
    "\n",
    "Further, methods to preload into a dendropy or ete3 tree object are available, in order to fit into many current workflows."
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "We can grab the <a href=\"//phyloxml.org\">PhyloXML</a> for the entire taxonomy."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 28,
   "metadata": {},
   "outputs": [],
   "source": [
    "xml = c.taxonomy.get(format='phyloxml')"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "We can retrieve a Newick string for the taxonomy. This can then be used in, for instance, <a href=\"//phylo.io\">Phylo.io</a>."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 29,
   "metadata": {},
   "outputs": [],
   "source": [
    "nwk = c.taxonomy.get(members=['PONAB', 'GORGO', 'PANPA', 'PANTR', 'HUMAN', 'NOMLE'], format='newick')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 30,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "((Pongo_abelii,(Gorilla_gorilla_gorilla,(Pan_paniscus,Pan_troglodytes)Pan,Homo_sapiens)Homininae)Hominidae,Nomascus_leucogenys)Hominoidea;\n"
     ]
    }
   ],
   "source": [
    "print(nwk)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "We can also use the methods to load dendropy / ete3 trees. Note, dendropy and ete3 are optional dependencies to the `omadb` package, so will not have been installed automatically."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 31,
   "metadata": {},
   "outputs": [],
   "source": [
    "dendropy_tree = c.taxonomy.dendropy_tree(root='Hominoidea')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 32,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "                  /------------------------------------------------------ PONAB\n",
      "                  |                                                            \n",
      "/-----------------+                 /------------------------------------ GORGO\n",
      "|                 |                 |                                          \n",
      "|                 |                 |                 /------------------ PANPA\n",
      "|                 \\-----------------+-----------------+                        \n",
      "+                                   |                 \\------------------ PANTR\n",
      "|                                   |                                          \n",
      "|                                   \\------------------------------------ HUMAN\n",
      "|                                                                              \n",
      "\\------------------------------------------------------------------------ NOMLE\n",
      "                                                                               \n",
      "                                                                               \n"
     ]
    }
   ],
   "source": [
    "print(dendropy_tree.as_ascii_plot())"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Alternatively, we can load with the species names instead of the UniProt species codes."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 33,
   "metadata": {},
   "outputs": [],
   "source": [
    "dendropy_tree = c.taxonomy.dendropy_tree(root='Hominoidea', with_names=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 34,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "             /----------------------------------------- Pongo abelii           \n",
      "             |                                                                 \n",
      "/------------+             /--------------------------- Gorilla gorilla gorilla\n",
      "|            |             |                                                   \n",
      "|            |             |             /------------- Pan paniscus           \n",
      "|            \\-------------+-------------+                                     \n",
      "+                          |             \\------------- Pan troglodytes        \n",
      "|                          |                                                   \n",
      "|                          \\--------------------------- Homo sapiens           \n",
      "|                                                                              \n",
      "\\------------------------------------------------------ Nomascus leucogenys    \n",
      "                                                                               \n",
      "                                                                               \n"
     ]
    }
   ],
   "source": [
    "print(dendropy_tree.as_ascii_plot())"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "We can also load into the ete3 tree, as so"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 35,
   "metadata": {},
   "outputs": [],
   "source": [
    "ete_tree = c.taxonomy.ete_tree(root='Hominoidea', with_names=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 36,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "\n",
      "      /-Pongo abelii\n",
      "     |\n",
      "   /-|   /-Gorilla gorilla gorilla\n",
      "  |  |  |\n",
      "  |  |  |   /-Pan paniscus\n",
      "  |   \\-|--|\n",
      "--|     |   \\-Pan troglodytes\n",
      "  |     |\n",
      "  |      \\-Homo sapiens\n",
      "  |\n",
      "   \\-Nomascus leucogenys\n"
     ]
    }
   ],
   "source": [
    "print(ete_tree)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "ETE also supports \"pretty\" plotting. For this, you will require PyQt4 (installable using: `conda install \"pyqt<5\"`)."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 37,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<IPython.core.display.Image object>"
      ]
     },
     "execution_count": 37,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "#ete_tree.render('%%inline')"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "---"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Example 4 - Visualising the Distribution of PAM Distances in the Taxonomic Space\n",
    "\n",
    "In this example, we compare the distribution of the evolutionary distance (in PAM units) between the 1:1 pairwise orthologues between Human and _Mus musculus_ (Mouse) as well as Human and _Canis lupus familiaris_ (Dog).\n",
    "\n",
    "We start by loading the pairwise data for 1:1 orthologues."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 38,
   "metadata": {},
   "outputs": [],
   "source": [
    "human_mouse_iter = c.pairwise(genome_id1='HUMAN',\n",
    "                              genome_id2='MOUSE',\n",
    "                              rel_type='1:1',\n",
    "                              progress=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 39,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "<omadb.OMARestAPI.ClientPagedResponse at 0x1a250452b0>"
      ]
     },
     "execution_count": 39,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "human_mouse_iter"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "We have recieved a \"PagedResponse\". As there are a lot of pairwise entries between then two genomes, the response size is limited. The object returned here is a generator which will lazily load the following page of results each time we get to the end.\n",
    "\n",
    "We can either use a for loop over this, or capture the entire response in one go. Here, we only want to extract the distance and don't care about any entry information."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 40,
   "metadata": {},
   "outputs": [
    {
     "name": "stderr",
     "output_type": "stream",
     "text": [
      "Loading pairs:  66%|██████▋   | 15860/23917 [00:12<00:06, 1281.17 entries/s]\n",
      "Loading pairs:  84%|████████▍ | 15349/18254 [00:08<00:01, 1762.42 entries/s]\n"
     ]
    }
   ],
   "source": [
    "import numpy as np\n",
    "\n",
    "human_mouse = np.array([x.distance for x in human_mouse_iter])\n",
    "\n",
    "human_dog = np.array([x.distance for x in c.pairwise(genome_id1='HUMAN',\n",
    "                                                     genome_id2='CANLF',\n",
    "                                                     rel_type='1:1',\n",
    "                                                     progress=True)])"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 41,
   "metadata": {},
   "outputs": [],
   "source": [
    "%matplotlib inline\n",
    "import seaborn as sns\n",
    "sns.set()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 42,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "<matplotlib.legend.Legend at 0x1a2901dcf8>"
      ]
     },
     "execution_count": 42,
     "metadata": {},
     "output_type": "execute_result"
    },
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<matplotlib.figure.Figure at 0x1a28f87d68>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "ax = sns.distplot(human_dog, label='Canis lupus familiaris')\n",
    "ax = sns.distplot(human_mouse, label='Mus musculus', ax=ax)\n",
    "\n",
    "ax.set_title('Distribution of Evolutionary Distance between\\n1:1 Orthologous Pairs HUMAN-{CANLF, MOUSE}')\n",
    "ax.set_xlabel('Evolutionary Distance (PAM)')\n",
    "ax.set_ylabel('Density')\n",
    "ax.legend()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 43,
   "metadata": {},
   "outputs": [],
   "source": [
    "from scipy import stats"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "We can use the two sample Kolmogorov-Smirnov test, available in scipy, in order to test whether the two samples are drawn from the same distribution."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 44,
   "metadata": {},
   "outputs": [],
   "source": [
    "z = stats.ks_2samp(human_mouse, human_dog)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 45,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "5.16481402754209e-90"
      ]
     },
     "execution_count": 45,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "z.pvalue"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "This indicates that they are not drawn from the same distribution.\n",
    "\n",
    "We can also look at the median / mean distance."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 46,
   "metadata": {},
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Median: \n",
      "HUMAN-MOUSE 11.774700164794922 \n",
      "HUMAN-CANLF 8.655900001525879\n",
      "Mean:\n",
      "HUMAN-MOUSE 16.42020220052249 \n",
      "HUMAN-CANLF 12.539905405603653\n"
     ]
    }
   ],
   "source": [
    "print('Median:',\n",
    "      '\\nHUMAN-MOUSE', np.median(human_mouse),\n",
    "      '\\nHUMAN-CANLF', np.median(human_dog))\n",
    "\n",
    "print('Mean:'\n",
    "      '\\nHUMAN-MOUSE', np.mean(human_mouse),\n",
    "      '\\nHUMAN-CANLF', np.mean(human_dog))"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "The mean distance between HUMAN and CANLF is less than that of HUMAN and MOUSE. This is consistent with previous observations that the rodent has a longer branch than humans and carnivores."
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "---"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "## Example 5 - annotating protein sequences not present in OMA\n",
    "\n",
    "Although the OMA database currently analyses over 2,100 genomes, many more have been sequenced, and the gap keeps on widening. It is nevertheless possible to use OMA to infer the function of custom protein sequences through a fast approximate search against all sequences in OMA."
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Here, we show this fast mapping, with a mystery gene (the cystic fibrosis transmembrane conductance regulator in the Emperor penguin -- `A0A087RGQ1_APTFO`)."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 47,
   "metadata": {},
   "outputs": [],
   "source": [
    "mystery_seq = 'FFFLLRWTKPILRKGYRRRLELSDIYQIPSADSADNLSEKLEREWDRELATSKKKPKLINALRRCFFWKFMFYGIILYLGEVTKSVQPLLLGRIIASYDPDNSDERSIAYYLAIGLCLLFLVRTLLIHPAIFGLHHIGMQMRIAMFSLIYKKILKLSSRVLDKISTGQLVSLLSNNLNKFDEGLALAHFVWIAPLQVALLMGLLWDMLEASAFSGLAFLIVLAFFQAWLGQRMMKYRNKRAGKINERLVITSEIIENIQSVKAYCWEDAMEKMIESIRETELKLTRKAAYVRYFNSSAFFFSGFFVVFLAVLPYAVIKGIILRKIFTTISFCIVLRMTVTRQFPGSVQTWYDSIGAINKIQDFLLKKEYKSLEYNLTTTGVELDKVTAFWDEGIGELFVKANQENNNSKAPSTDNNLFFSNFPLHASPVLQDINFKIEKGQLLAVSGSTGAGKTSLLMLIMGELEPSQGRLKHSGRISFSPQVSWIMPGTIKENIIFGVSYDEYRYKSVIKACQLEEDISKFPDKDYTVLGDGGIILSGGQRARISLARAVYKDADLYLLDSPFGHLDIFTEKEIFESCVCKLMANKTRILVTSKLEHLKIADKILILHEGSCYFYGTFSELQGQRPDFSSELMGFDSFDQFSAERRNSILTETLRRFSIEGEGTGSRNEIKKQSFKQTSDFNDKRKNSIIINPLNASRKFSVVQRNGMQVNGIEDGHNDPPERRFSLVPDLEQGDVGLLRSSMLNTDHILQGRRRQSVLNLMTGTSVNYGPNFSKKGSTTFRKMSMVPQTNLSSEIDIYTRRLSRDSVLDITDEINEEDLKECFTDDAESMGTVTTWNTYFRYVTIHKNLIFVLILCVTVFLVEVAASLAGLWFLKQTALKANTTQSENSTSDKPPVIVTVTSSYYIIYIYVGVADTLLAMGIFRGLPLVHTLITVSKTLHQKMVHAVLHAPMSTFNSWKAGGMLNRFSKDTAVLDDLLPLTVFDFIQLILIVIGAITVVSILQPYIFLASVPVIAAFILLRAYFLHTSQQLKQLESEARSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHKALNLHTANWFLYLSTLRWFQMRIEMIFVVFFVAVAFISIVTTGDGSGKVGIILTLAMNIMGTLQWAVNSSIDVDSLMRSVGRIFKFIDMPTEEMKNIKPHKNNQFSDALVIENRHAKEEKNWPSGGQMTVKDLTAKYSEGGAAVLENISFSISSGQRVGLLGRTGSGKSTLLFAFLRLLNTEGDIQIDGVSWSTVSVQQWRKAFGVIPQKVFIFSGTFRMNLDPYGQWNDEEIWKVAEEVGLKSVIEQFPGQLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPVTSQVIRKTLKHAFANCTVILSEHRLEAMLECQRFLVIEDNKLRQYESIQKLLNEKSSFRQAISHADRLKLLPVHHRNSSKRKPRPKITALQEETEEEVQETRL'"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 48,
   "metadata": {},
   "outputs": [],
   "source": [
    "res = c.function(mystery_seq)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "This returns a list of results. The first is of the form"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 49,
   "metadata": {},
   "outputs": [
    {
     "data": {
      "text/plain": [
       "{'Aspect': 'F',\n",
       " 'Assigned_By': 'OMA_FastMap',\n",
       " 'DB': 'OMA_FastMap',\n",
       " 'DB:Reference': 'OMA_Fun:002',\n",
       " 'DB_Object_Name': '',\n",
       " 'DB_Object_Type': 'protein',\n",
       " 'Date': '20180807',\n",
       " 'Evidence': 'IEA',\n",
       " 'GO_ID': 'GO:0000166',\n",
       " 'GO_name': 'nucleotide binding',\n",
       " 'Qualifier': '',\n",
       " 'Synonym': '',\n",
       " 'With': 'Approx:TAEGU04269:11919.380438514474'}"
      ]
     },
     "execution_count": 49,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "res[0]"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "All list-typed returns are possible to load as a pandas data frame (`pd.DataFrame`), instead. To do this, the following call can be made."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 50,
   "metadata": {},
   "outputs": [],
   "source": [
    "df = c.function(mystery_seq, as_dataframe=True)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 51,
   "metadata": {
    "scrolled": true
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
       "    .dataframe tbody tr th:only-of-type {\n",
       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>Aspect</th>\n",
       "      <th>Assigned_By</th>\n",
       "      <th>DB</th>\n",
       "      <th>DB:Reference</th>\n",
       "      <th>DB_Object_Name</th>\n",
       "      <th>DB_Object_Type</th>\n",
       "      <th>Date</th>\n",
       "      <th>Evidence</th>\n",
       "      <th>GO_ID</th>\n",
       "      <th>GO_name</th>\n",
       "      <th>Qualifier</th>\n",
       "      <th>Synonym</th>\n",
       "      <th>With</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>F</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0000166</td>\n",
       "      <td>nucleotide binding</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>F</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0005254</td>\n",
       "      <td>chloride channel activity</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>2</th>\n",
       "      <td>F</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0005260</td>\n",
       "      <td>intracellularly ATP-gated chloride channel act...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>3</th>\n",
       "      <td>F</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0005524</td>\n",
       "      <td>ATP binding</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>4</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0005737</td>\n",
       "      <td>cytoplasm</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>5</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0005769</td>\n",
       "      <td>early endosome</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>6</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0005789</td>\n",
       "      <td>endoplasmic reticulum membrane</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>7</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0005829</td>\n",
       "      <td>cytosol</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>8</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0005886</td>\n",
       "      <td>plasma membrane</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>9</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0005887</td>\n",
       "      <td>integral component of plasma membrane</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>10</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0006695</td>\n",
       "      <td>cholesterol biosynthetic process</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>11</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0006811</td>\n",
       "      <td>ion transport</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>12</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0006821</td>\n",
       "      <td>chloride transport</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>13</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0006904</td>\n",
       "      <td>vesicle docking involved in exocytosis</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>14</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0009986</td>\n",
       "      <td>cell surface</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>15</th>\n",
       "      <td>F</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0015106</td>\n",
       "      <td>bicarbonate transmembrane transporter activity</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>16</th>\n",
       "      <td>F</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0015108</td>\n",
       "      <td>chloride transmembrane transporter activity</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>17</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0015701</td>\n",
       "      <td>bicarbonate transport</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>18</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0016020</td>\n",
       "      <td>membrane</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>19</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0016021</td>\n",
       "      <td>integral component of membrane</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>20</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0016324</td>\n",
       "      <td>apical plasma membrane</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>21</th>\n",
       "      <td>F</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0016787</td>\n",
       "      <td>hydrolase activity</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>22</th>\n",
       "      <td>F</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0016887</td>\n",
       "      <td>ATPase activity</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>23</th>\n",
       "      <td>F</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0019869</td>\n",
       "      <td>chloride channel inhibitor activity</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>24</th>\n",
       "      <td>F</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0019899</td>\n",
       "      <td>enzyme binding</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>25</th>\n",
       "      <td>F</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0030165</td>\n",
       "      <td>PDZ domain binding</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>26</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0030301</td>\n",
       "      <td>cholesterol transport</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>27</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0031205</td>\n",
       "      <td>endoplasmic reticulum Sec complex</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>28</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0032991</td>\n",
       "      <td>protein-containing complex</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>29</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0034707</td>\n",
       "      <td>chloride channel complex</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>30</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0035377</td>\n",
       "      <td>transepithelial water transport</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>31</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0035774</td>\n",
       "      <td>positive regulation of insulin secretion invol...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>32</th>\n",
       "      <td>F</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0042626</td>\n",
       "      <td>ATPase activity, coupled to transmembrane move...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>33</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0045921</td>\n",
       "      <td>positive regulation of exocytosis</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>34</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0048240</td>\n",
       "      <td>sperm capacitation</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>35</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0050891</td>\n",
       "      <td>multicellular organismal water homeostasis</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>36</th>\n",
       "      <td>F</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0051087</td>\n",
       "      <td>chaperone binding</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>37</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0051454</td>\n",
       "      <td>intracellular pH elevation</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>38</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0055037</td>\n",
       "      <td>recycling endosome</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>39</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0055085</td>\n",
       "      <td>transmembrane transport</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>40</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0060081</td>\n",
       "      <td>membrane hyperpolarization</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>41</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0071320</td>\n",
       "      <td>cellular response to cAMP</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>42</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:1902161</td>\n",
       "      <td>positive regulation of cyclic nucleotide-gated...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>43</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:1902476</td>\n",
       "      <td>chloride transmembrane transport</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>44</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:1902943</td>\n",
       "      <td>positive regulation of voltage-gated chloride ...</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>45</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:1904322</td>\n",
       "      <td>cellular response to forskolin</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>46</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0000003</td>\n",
       "      <td>reproduction</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>47</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0005634</td>\n",
       "      <td>nucleus</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>48</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0005768</td>\n",
       "      <td>endosome</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>49</th>\n",
       "      <td>C</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0005783</td>\n",
       "      <td>endoplasmic reticulum</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>50</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0010243</td>\n",
       "      <td>response to organonitrogen compound</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>51</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0035690</td>\n",
       "      <td>cellular response to drug</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>52</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0046677</td>\n",
       "      <td>response to antibiotic</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>53</th>\n",
       "      <td>P</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_FastMap</td>\n",
       "      <td>OMA_Fun:002</td>\n",
       "      <td></td>\n",
       "      <td>protein</td>\n",
       "      <td>20180807</td>\n",
       "      <td>IEA</td>\n",
       "      <td>GO:0071407</td>\n",
       "      <td>cellular response to organic cyclic compound</td>\n",
       "      <td></td>\n",
       "      <td></td>\n",
       "      <td>Approx:TAEGU04269:11919.380438514474</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "   Aspect  Assigned_By           DB DB:Reference DB_Object_Name  \\\n",
       "0       F  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "1       F  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "2       F  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "3       F  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "4       C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "5       C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "6       C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "7       C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "8       C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "9       C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "10      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "11      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "12      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "13      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "14      C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "15      F  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "16      F  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "17      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "18      C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "19      C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "20      C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "21      F  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "22      F  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "23      F  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "24      F  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "25      F  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "26      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "27      C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "28      C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "29      C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "30      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "31      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "32      F  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "33      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "34      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "35      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "36      F  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "37      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "38      C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "39      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "40      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "41      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "42      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "43      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "44      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "45      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "46      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "47      C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "48      C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "49      C  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "50      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "51      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "52      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "53      P  OMA_FastMap  OMA_FastMap  OMA_Fun:002                  \n",
       "\n",
       "   DB_Object_Type      Date Evidence       GO_ID  \\\n",
       "0         protein  20180807      IEA  GO:0000166   \n",
       "1         protein  20180807      IEA  GO:0005254   \n",
       "2         protein  20180807      IEA  GO:0005260   \n",
       "3         protein  20180807      IEA  GO:0005524   \n",
       "4         protein  20180807      IEA  GO:0005737   \n",
       "5         protein  20180807      IEA  GO:0005769   \n",
       "6         protein  20180807      IEA  GO:0005789   \n",
       "7         protein  20180807      IEA  GO:0005829   \n",
       "8         protein  20180807      IEA  GO:0005886   \n",
       "9         protein  20180807      IEA  GO:0005887   \n",
       "10        protein  20180807      IEA  GO:0006695   \n",
       "11        protein  20180807      IEA  GO:0006811   \n",
       "12        protein  20180807      IEA  GO:0006821   \n",
       "13        protein  20180807      IEA  GO:0006904   \n",
       "14        protein  20180807      IEA  GO:0009986   \n",
       "15        protein  20180807      IEA  GO:0015106   \n",
       "16        protein  20180807      IEA  GO:0015108   \n",
       "17        protein  20180807      IEA  GO:0015701   \n",
       "18        protein  20180807      IEA  GO:0016020   \n",
       "19        protein  20180807      IEA  GO:0016021   \n",
       "20        protein  20180807      IEA  GO:0016324   \n",
       "21        protein  20180807      IEA  GO:0016787   \n",
       "22        protein  20180807      IEA  GO:0016887   \n",
       "23        protein  20180807      IEA  GO:0019869   \n",
       "24        protein  20180807      IEA  GO:0019899   \n",
       "25        protein  20180807      IEA  GO:0030165   \n",
       "26        protein  20180807      IEA  GO:0030301   \n",
       "27        protein  20180807      IEA  GO:0031205   \n",
       "28        protein  20180807      IEA  GO:0032991   \n",
       "29        protein  20180807      IEA  GO:0034707   \n",
       "30        protein  20180807      IEA  GO:0035377   \n",
       "31        protein  20180807      IEA  GO:0035774   \n",
       "32        protein  20180807      IEA  GO:0042626   \n",
       "33        protein  20180807      IEA  GO:0045921   \n",
       "34        protein  20180807      IEA  GO:0048240   \n",
       "35        protein  20180807      IEA  GO:0050891   \n",
       "36        protein  20180807      IEA  GO:0051087   \n",
       "37        protein  20180807      IEA  GO:0051454   \n",
       "38        protein  20180807      IEA  GO:0055037   \n",
       "39        protein  20180807      IEA  GO:0055085   \n",
       "40        protein  20180807      IEA  GO:0060081   \n",
       "41        protein  20180807      IEA  GO:0071320   \n",
       "42        protein  20180807      IEA  GO:1902161   \n",
       "43        protein  20180807      IEA  GO:1902476   \n",
       "44        protein  20180807      IEA  GO:1902943   \n",
       "45        protein  20180807      IEA  GO:1904322   \n",
       "46        protein  20180807      IEA  GO:0000003   \n",
       "47        protein  20180807      IEA  GO:0005634   \n",
       "48        protein  20180807      IEA  GO:0005768   \n",
       "49        protein  20180807      IEA  GO:0005783   \n",
       "50        protein  20180807      IEA  GO:0010243   \n",
       "51        protein  20180807      IEA  GO:0035690   \n",
       "52        protein  20180807      IEA  GO:0046677   \n",
       "53        protein  20180807      IEA  GO:0071407   \n",
       "\n",
       "                                              GO_name Qualifier Synonym  \\\n",
       "0                                  nucleotide binding                     \n",
       "1                           chloride channel activity                     \n",
       "2   intracellularly ATP-gated chloride channel act...                     \n",
       "3                                         ATP binding                     \n",
       "4                                           cytoplasm                     \n",
       "5                                      early endosome                     \n",
       "6                      endoplasmic reticulum membrane                     \n",
       "7                                             cytosol                     \n",
       "8                                     plasma membrane                     \n",
       "9               integral component of plasma membrane                     \n",
       "10                   cholesterol biosynthetic process                     \n",
       "11                                      ion transport                     \n",
       "12                                 chloride transport                     \n",
       "13             vesicle docking involved in exocytosis                     \n",
       "14                                       cell surface                     \n",
       "15     bicarbonate transmembrane transporter activity                     \n",
       "16        chloride transmembrane transporter activity                     \n",
       "17                              bicarbonate transport                     \n",
       "18                                           membrane                     \n",
       "19                     integral component of membrane                     \n",
       "20                             apical plasma membrane                     \n",
       "21                                 hydrolase activity                     \n",
       "22                                    ATPase activity                     \n",
       "23                chloride channel inhibitor activity                     \n",
       "24                                     enzyme binding                     \n",
       "25                                 PDZ domain binding                     \n",
       "26                              cholesterol transport                     \n",
       "27                  endoplasmic reticulum Sec complex                     \n",
       "28                         protein-containing complex                     \n",
       "29                           chloride channel complex                     \n",
       "30                    transepithelial water transport                     \n",
       "31  positive regulation of insulin secretion invol...                     \n",
       "32  ATPase activity, coupled to transmembrane move...                     \n",
       "33                  positive regulation of exocytosis                     \n",
       "34                                 sperm capacitation                     \n",
       "35         multicellular organismal water homeostasis                     \n",
       "36                                  chaperone binding                     \n",
       "37                         intracellular pH elevation                     \n",
       "38                                 recycling endosome                     \n",
       "39                            transmembrane transport                     \n",
       "40                         membrane hyperpolarization                     \n",
       "41                          cellular response to cAMP                     \n",
       "42  positive regulation of cyclic nucleotide-gated...                     \n",
       "43                   chloride transmembrane transport                     \n",
       "44  positive regulation of voltage-gated chloride ...                     \n",
       "45                     cellular response to forskolin                     \n",
       "46                                       reproduction                     \n",
       "47                                            nucleus                     \n",
       "48                                           endosome                     \n",
       "49                              endoplasmic reticulum                     \n",
       "50                response to organonitrogen compound                     \n",
       "51                          cellular response to drug                     \n",
       "52                             response to antibiotic                     \n",
       "53       cellular response to organic cyclic compound                     \n",
       "\n",
       "                                    With  \n",
       "0   Approx:TAEGU04269:11919.380438514474  \n",
       "1   Approx:TAEGU04269:11919.380438514474  \n",
       "2   Approx:TAEGU04269:11919.380438514474  \n",
       "3   Approx:TAEGU04269:11919.380438514474  \n",
       "4   Approx:TAEGU04269:11919.380438514474  \n",
       "5   Approx:TAEGU04269:11919.380438514474  \n",
       "6   Approx:TAEGU04269:11919.380438514474  \n",
       "7   Approx:TAEGU04269:11919.380438514474  \n",
       "8   Approx:TAEGU04269:11919.380438514474  \n",
       "9   Approx:TAEGU04269:11919.380438514474  \n",
       "10  Approx:TAEGU04269:11919.380438514474  \n",
       "11  Approx:TAEGU04269:11919.380438514474  \n",
       "12  Approx:TAEGU04269:11919.380438514474  \n",
       "13  Approx:TAEGU04269:11919.380438514474  \n",
       "14  Approx:TAEGU04269:11919.380438514474  \n",
       "15  Approx:TAEGU04269:11919.380438514474  \n",
       "16  Approx:TAEGU04269:11919.380438514474  \n",
       "17  Approx:TAEGU04269:11919.380438514474  \n",
       "18  Approx:TAEGU04269:11919.380438514474  \n",
       "19  Approx:TAEGU04269:11919.380438514474  \n",
       "20  Approx:TAEGU04269:11919.380438514474  \n",
       "21  Approx:TAEGU04269:11919.380438514474  \n",
       "22  Approx:TAEGU04269:11919.380438514474  \n",
       "23  Approx:TAEGU04269:11919.380438514474  \n",
       "24  Approx:TAEGU04269:11919.380438514474  \n",
       "25  Approx:TAEGU04269:11919.380438514474  \n",
       "26  Approx:TAEGU04269:11919.380438514474  \n",
       "27  Approx:TAEGU04269:11919.380438514474  \n",
       "28  Approx:TAEGU04269:11919.380438514474  \n",
       "29  Approx:TAEGU04269:11919.380438514474  \n",
       "30  Approx:TAEGU04269:11919.380438514474  \n",
       "31  Approx:TAEGU04269:11919.380438514474  \n",
       "32  Approx:TAEGU04269:11919.380438514474  \n",
       "33  Approx:TAEGU04269:11919.380438514474  \n",
       "34  Approx:TAEGU04269:11919.380438514474  \n",
       "35  Approx:TAEGU04269:11919.380438514474  \n",
       "36  Approx:TAEGU04269:11919.380438514474  \n",
       "37  Approx:TAEGU04269:11919.380438514474  \n",
       "38  Approx:TAEGU04269:11919.380438514474  \n",
       "39  Approx:TAEGU04269:11919.380438514474  \n",
       "40  Approx:TAEGU04269:11919.380438514474  \n",
       "41  Approx:TAEGU04269:11919.380438514474  \n",
       "42  Approx:TAEGU04269:11919.380438514474  \n",
       "43  Approx:TAEGU04269:11919.380438514474  \n",
       "44  Approx:TAEGU04269:11919.380438514474  \n",
       "45  Approx:TAEGU04269:11919.380438514474  \n",
       "46  Approx:TAEGU04269:11919.380438514474  \n",
       "47  Approx:TAEGU04269:11919.380438514474  \n",
       "48  Approx:TAEGU04269:11919.380438514474  \n",
       "49  Approx:TAEGU04269:11919.380438514474  \n",
       "50  Approx:TAEGU04269:11919.380438514474  \n",
       "51  Approx:TAEGU04269:11919.380438514474  \n",
       "52  Approx:TAEGU04269:11919.380438514474  \n",
       "53  Approx:TAEGU04269:11919.380438514474  "
      ]
     },
     "execution_count": 51,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "df"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "This results in 54 GO annotations. By comparison, this sequence has merely 15 GO annotations in UniProt-GOA — all of which are also predicted by this method in OMA."
   ]
  }
 ],
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