diff --git a/lib/datadog/tracing/configuration/ext.rb b/lib/datadog/tracing/configuration/ext.rb
index 68bed3ed546..afb4a19acf6 100644
--- a/lib/datadog/tracing/configuration/ext.rb
+++ b/lib/datadog/tracing/configuration/ext.rb
@@ -32,7 +32,7 @@ module Correlation
         # @public_api
         module Distributed
           # Custom Datadog format
-          PROPAGATION_STYLE_DATADOG = 'Datadog'
+          PROPAGATION_STYLE_DATADOG = 'datadog'
 
           PROPAGATION_STYLE_B3_MULTI_HEADER = 'b3multi'
           PROPAGATION_STYLE_B3_SINGLE_HEADER = 'b3'
diff --git a/lib/datadog/tracing/configuration/settings.rb b/lib/datadog/tracing/configuration/settings.rb
index e7727c6288d..558af6497ba 100644
--- a/lib/datadog/tracing/configuration/settings.rb
+++ b/lib/datadog/tracing/configuration/settings.rb
@@ -42,14 +42,14 @@ def self.extended(base)
               #
               # @public_api
               settings :distributed_tracing do
-                # An ordered list of what data propagation styles the tracer will use to extract distributed tracing propagation
+                # An ordered, case-insensitive list of what data propagation styles the tracer will use to extract distributed tracing propagation
                 # data from incoming requests and messages.
                 #
                 # The tracer will try to find distributed headers in the order they are present in the list provided to this option.
                 # The first format to have valid data present will be used.
                 #
                 # @default `DD_TRACE_PROPAGATION_STYLE_EXTRACT` environment variable (comma-separated list),
-                #   otherwise `['Datadog','b3multi','b3']`.
+                #   otherwise `['datadog','b3multi','b3']`.
                 # @return [Array<String>]
                 option :propagation_extract_style do |o|
                   o.type :array
@@ -60,14 +60,18 @@ def self.extended(base)
                       Tracing::Configuration::Ext::Distributed::PROPAGATION_STYLE_TRACE_CONTEXT,
                     ]
                   )
+                  o.after_set do |styles|
+                    # Make values case-insensitive
+                    styles.map!(&:downcase)
+                  end
                 end
 
-                # The data propagation styles the tracer will use to inject distributed tracing propagation
+                # The case-insensitive list of the data propagation styles the tracer will use to inject distributed tracing propagation
                 # data into outgoing requests and messages.
                 #
                 # The tracer will inject data from all styles specified in this option.
                 #
-                # @default `DD_TRACE_PROPAGATION_STYLE_INJECT` environment variable (comma-separated list), otherwise `['Datadog']`.
+                # @default `DD_TRACE_PROPAGATION_STYLE_INJECT` environment variable (comma-separated list), otherwise `['datadog','tracecontext']`.
                 # @return [Array<String>]
                 option :propagation_inject_style do |o|
                   o.type :array
@@ -76,9 +80,13 @@ def self.extended(base)
                     Tracing::Configuration::Ext::Distributed::PROPAGATION_STYLE_DATADOG,
                     Tracing::Configuration::Ext::Distributed::PROPAGATION_STYLE_TRACE_CONTEXT,
                   ]
+                  o.after_set do |styles|
+                    # Make values case-insensitive
+                    styles.map!(&:downcase)
+                  end
                 end
 
-                # An ordered list of what data propagation styles the tracer will use to extract distributed tracing propagation
+                # An ordered, case-insensitive list of what data propagation styles the tracer will use to extract distributed tracing propagation
                 # data from incoming requests and inject into outgoing requests.
                 #
                 # This configuration is the equivalent of configuring both {propagation_extract_style}
@@ -93,6 +101,9 @@ def self.extended(base)
                   o.after_set do |styles|
                     next if styles.empty?
 
+                    # Make values case-insensitive
+                    styles.map!(&:downcase)
+
                     set_option(:propagation_extract_style, styles)
                     set_option(:propagation_inject_style, styles)
                   end
diff --git a/spec/datadog/opentelemetry_spec.rb b/spec/datadog/opentelemetry_spec.rb
index edfad383866..51b2740d370 100644
--- a/spec/datadog/opentelemetry_spec.rb
+++ b/spec/datadog/opentelemetry_spec.rb
@@ -16,7 +16,7 @@
       Datadog.configure do |c|
         c.tracing.writer = writer_
         c.tracing.partial_flush.min_spans_threshold = 1 # Ensure tests flush spans quickly
-        c.tracing.distributed_tracing.propagation_style = ['Datadog'] # Ensure test has consistent propagation configuration
+        c.tracing.distributed_tracing.propagation_style = ['datadog'] # Ensure test has consistent propagation configuration
       end
 
       ::OpenTelemetry::SDK.configure do |c|
@@ -732,7 +732,7 @@ def headers
 
           before do
             Datadog.configure do |c|
-              c.tracing.distributed_tracing.propagation_extract_style = ['Datadog', 'tracecontext']
+              c.tracing.distributed_tracing.propagation_extract_style = ['datadog', 'tracecontext']
             end
           end
 
diff --git a/spec/datadog/opentracer/rack_propagator_spec.rb b/spec/datadog/opentracer/rack_propagator_spec.rb
index d2a9af36ae3..4a1b22dfb2b 100644
--- a/spec/datadog/opentracer/rack_propagator_spec.rb
+++ b/spec/datadog/opentracer/rack_propagator_spec.rb
@@ -24,7 +24,7 @@
 
     before do
       Datadog.configure do |c|
-        c.tracing.distributed_tracing.propagation_style = ['Datadog']
+        c.tracing.distributed_tracing.propagation_style = ['datadog']
       end
 
       # Expect carrier to be set with Datadog trace properties
diff --git a/spec/datadog/tracing/configuration/settings_spec.rb b/spec/datadog/tracing/configuration/settings_spec.rb
index f0166abf5f1..647b26322be 100644
--- a/spec/datadog/tracing/configuration/settings_spec.rb
+++ b/spec/datadog/tracing/configuration/settings_spec.rb
@@ -92,6 +92,19 @@
                 ]
               )
             end
+
+            context 'with a mixed case value' do
+              let(:var_value) { 'B3Multi,B3' }
+
+              it 'parses in a case-insensitive manner' do
+                is_expected.to eq(
+                  [
+                    Datadog::Tracing::Configuration::Ext::Distributed::PROPAGATION_STYLE_B3_MULTI_HEADER,
+                    Datadog::Tracing::Configuration::Ext::Distributed::PROPAGATION_STYLE_B3_SINGLE_HEADER
+                  ]
+                )
+              end
+            end
           end
         end
       end
@@ -114,7 +127,7 @@
           end
 
           context 'is defined' do
-            let(:var_value) { 'Datadog,b3' }
+            let(:var_value) { 'datadog,b3' }
 
             it do
               is_expected.to eq(
@@ -124,6 +137,19 @@
                 ]
               )
             end
+
+            context 'with a mixed case value' do
+              let(:var_value) { 'Datadog,B3' }
+
+              it 'parses in a case-insensitive manner' do
+                is_expected.to eq(
+                  [
+                    Datadog::Tracing::Configuration::Ext::Distributed::PROPAGATION_STYLE_DATADOG,
+                    Datadog::Tracing::Configuration::Ext::Distributed::PROPAGATION_STYLE_B3_SINGLE_HEADER
+                  ]
+                )
+              end
+            end
           end
         end
       end
@@ -148,11 +174,11 @@ def propagation_inject_style
             it { is_expected.to eq [] }
 
             it 'does not change propagation_extract_style' do
-              expect { propagation_style }.to_not change { propagation_extract_style }.from(%w[Datadog tracecontext])
+              expect { propagation_style }.to_not change { propagation_extract_style }.from(%w[datadog tracecontext])
             end
 
             it 'does not change propagation_inject_style' do
-              expect { propagation_style }.to_not change { propagation_inject_style }.from(%w[Datadog tracecontext])
+              expect { propagation_style }.to_not change { propagation_inject_style }.from(%w[datadog tracecontext])
             end
           end
 
@@ -168,6 +194,14 @@ def propagation_inject_style
             it 'sets propagation_inject_style' do
               expect { propagation_style }.to change { propagation_inject_style }.to(%w[b3multi b3])
             end
+
+            context 'with a mixed case value' do
+              let(:var_value) { 'b3MULTI' }
+
+              it 'parses in a case-insensitive manner' do
+                expect { propagation_style }.to change { propagation_extract_style }.to(%w[b3multi])
+              end
+            end
           end
         end
       end
diff --git a/spec/datadog/tracing/contrib/grpc/distributed/propagation_spec.rb b/spec/datadog/tracing/contrib/grpc/distributed/propagation_spec.rb
index a063078707e..aac699d71c1 100644
--- a/spec/datadog/tracing/contrib/grpc/distributed/propagation_spec.rb
+++ b/spec/datadog/tracing/contrib/grpc/distributed/propagation_spec.rb
@@ -54,7 +54,7 @@
 
   context 'for Datadog' do
     it_behaves_like 'Datadog distributed format' do
-      before { Datadog.configure { |c| c.tracing.distributed_tracing.propagation_style = ['Datadog'] } }
+      before { Datadog.configure { |c| c.tracing.distributed_tracing.propagation_style = ['datadog'] } }
       let(:datadog) { propagation }
     end
   end
diff --git a/spec/datadog/tracing/contrib/http/distributed/propagation_spec.rb b/spec/datadog/tracing/contrib/http/distributed/propagation_spec.rb
index 33fc58cb4ea..3e9b6f01fa1 100644
--- a/spec/datadog/tracing/contrib/http/distributed/propagation_spec.rb
+++ b/spec/datadog/tracing/contrib/http/distributed/propagation_spec.rb
@@ -39,7 +39,7 @@
 
   context 'for Datadog' do
     it_behaves_like 'Datadog distributed format' do
-      before { Datadog.configure { |c| c.tracing.distributed_tracing.propagation_style = ['Datadog'] } }
+      before { Datadog.configure { |c| c.tracing.distributed_tracing.propagation_style = ['datadog'] } }
       let(:datadog) { propagation }
     end
   end
diff --git a/spec/datadog/tracing/distributed/propagation_spec.rb b/spec/datadog/tracing/distributed/propagation_spec.rb
index 0a9ddd0a781..d726ef942f0 100644
--- a/spec/datadog/tracing/distributed/propagation_spec.rb
+++ b/spec/datadog/tracing/distributed/propagation_spec.rb
@@ -7,7 +7,7 @@
 
   let(:propagation_styles) do
     {
-      'Datadog' => Datadog::Tracing::Distributed::Datadog.new(fetcher: fetcher_class),
+      'datadog' => Datadog::Tracing::Distributed::Datadog.new(fetcher: fetcher_class),
       'tracecontext' => Datadog::Tracing::Distributed::TraceContext.new(fetcher: fetcher_class),
     }
   end