diff --git a/pkg/util/kubernetes/autoscalers/processor.go b/pkg/util/kubernetes/autoscalers/processor.go
index 3a3bfdb0d81097..9107e9177e59c9 100644
--- a/pkg/util/kubernetes/autoscalers/processor.go
+++ b/pkg/util/kubernetes/autoscalers/processor.go
@@ -122,10 +122,14 @@ func (p *Processor) UpdateExternalMetrics(emList map[string]custommetrics.Extern
 	var err error
 	updated = make(map[string]custommetrics.ExternalMetricValue)
 
-	batch := []string{}
+	uniqueQueries := make(map[string]struct{}, len(emList))
+	batch := make([]string, 0, len(emList))
 	for _, e := range emList {
 		q := getKey(e.MetricName, e.Labels, aggregator, rollup)
-		batch = append(batch, q)
+		if _, found := uniqueQueries[q]; !found {
+			uniqueQueries[q] = struct{}{}
+			batch = append(batch, q)
+		}
 	}
 
 	metrics, err := p.QueryExternalMetric(batch)
diff --git a/pkg/util/kubernetes/autoscalers/processor_test.go b/pkg/util/kubernetes/autoscalers/processor_test.go
index 776fa9953cbca4..a0e196cee2439b 100644
--- a/pkg/util/kubernetes/autoscalers/processor_test.go
+++ b/pkg/util/kubernetes/autoscalers/processor_test.go
@@ -107,6 +107,46 @@ func TestProcessor_UpdateExternalMetrics(t *testing.T) {
 				},
 			},
 		},
+		{
+			"perform unique from list of input externalMetrics",
+			map[string]custommetrics.ExternalMetricValue{
+				"id1": {
+					MetricName: metricName,
+					Labels:     map[string]string{"foo": "bar"},
+					Valid:      false,
+				},
+				"id2": {
+					MetricName: metricName,
+					Labels:     map[string]string{"foo": "bar"},
+					Valid:      false,
+				},
+			},
+			[]datadog.Series{
+				{
+					Metric: &metricName,
+					Points: []datadog.DataPoint{
+						makePoints(1531492452000, 12),
+						makePoints(penTime, 14), // Force the penultimate point to be considered fresh at all time(< externalMaxAge)
+						makePoints(0, 27),
+					},
+					Scope: makePtr("foo:bar"),
+				},
+			},
+			map[string]custommetrics.ExternalMetricValue{
+				"id1": {
+					MetricName: "requests_per_s",
+					Labels:     map[string]string{"foo": "bar"},
+					Value:      14,
+					Valid:      true,
+				},
+				"id2": {
+					MetricName: "requests_per_s",
+					Labels:     map[string]string{"foo": "bar"},
+					Value:      14,
+					Valid:      true,
+				},
+			},
+		},
 		{
 			"do not update valid sparse metric",
 			map[string]custommetrics.ExternalMetricValue{
diff --git a/releasenotes-dca/notes/fix-duplicate-queries-external-metrics-a9489dd3eb4d2ca8.yaml b/releasenotes-dca/notes/fix-duplicate-queries-external-metrics-a9489dd3eb4d2ca8.yaml
new file mode 100644
index 00000000000000..94c116f3fab770
--- /dev/null
+++ b/releasenotes-dca/notes/fix-duplicate-queries-external-metrics-a9489dd3eb4d2ca8.yaml
@@ -0,0 +1,4 @@
+---
+fixes:
+  - |
+    Fix issue in Cluster Agent when using external metrics without DatadogMetrics where multiple HPAs using the same metricName + Labels would prevent all HPAs (except 1st one) to get values from Datadog