diff --git a/src/DIRAC/TransformationSystem/Agent/TransformationCleaningAgent.py b/src/DIRAC/TransformationSystem/Agent/TransformationCleaningAgent.py
index 327c554c920..8f5f3d5a433 100644
--- a/src/DIRAC/TransformationSystem/Agent/TransformationCleaningAgent.py
+++ b/src/DIRAC/TransformationSystem/Agent/TransformationCleaningAgent.py
@@ -12,7 +12,9 @@
 import errno
 import os
 import re
+import time
 from datetime import datetime, timedelta
+from hashlib import md5
 
 # # from DIRAC
 from DIRAC import S_ERROR, S_OK
@@ -24,7 +26,11 @@
 from DIRAC.Core.Utilities.Proxy import executeWithUserProxy
 from DIRAC.Core.Utilities.ReturnValues import returnSingleResult
 from DIRAC.DataManagementSystem.Client.DataManager import DataManager
+from DIRAC.RequestManagementSystem.Client.File import File
+from DIRAC.RequestManagementSystem.Client.Operation import Operation
 from DIRAC.RequestManagementSystem.Client.ReqClient import ReqClient
+from DIRAC.RequestManagementSystem.Client.Request import Request
+from DIRAC.RequestManagementSystem.private.RequestValidator import RequestValidator
 from DIRAC.Resources.Catalog.FileCatalog import FileCatalog
 from DIRAC.Resources.Catalog.FileCatalogClient import FileCatalogClient
 from DIRAC.Resources.Storage.StorageElement import StorageElement
@@ -74,6 +80,7 @@ def __init__(self, *args, **kwargs):
         self.logSE = "LogSE"
         # # enable/disable execution
         self.enableFlag = "True"
+        self.cleanWithRMS = False
 
         self.dataProcTTypes = ["MCSimulation", "Merge"]
         self.dataManipTTypes = ["Replication", "Removal"]
@@ -113,6 +120,7 @@ def initialize(self):
         self.logSE = Operations().getValue("/LogStorage/LogSE", self.logSE)
         self.log.info(f"Will remove logs found on storage element: {self.logSE}")
 
+        self.cleanWithRMS = self.am_getOption("CleanWithRMS", self.cleanWithRMS)
         # # transformation client
         self.transClient = TransformationClient()
         # # wms client
@@ -387,6 +395,11 @@ def cleanContent(self, directory):
         # Executing with shifter proxy
         gConfigurationData.setOptionInCFG("/DIRAC/Security/UseServerCertificate", "false")
         failed = {}
+        if self.cleanWithRMS:
+            res = self.__submitRemovalRequests(filesFound, 0)
+            gConfigurationData.setOptionInCFG("/DIRAC/Security/UseServerCertificate", "true")
+            return res
+
         for chunkId, filesChunk in enumerate(breakListIntoChunks(filesFound, 500)):
             self.log.info("Removing chunk", chunkId)
             res = DataManager().removeFile(filesChunk, force=True)
@@ -567,10 +580,13 @@ def cleanMetadataCatalogFiles(self, transID):
             self.log.info("No files found for transID", transID)
             return S_OK()
 
-        # Executing with shifter proxy
-        gConfigurationData.setOptionInCFG("/DIRAC/Security/UseServerCertificate", "false")
-        res = DataManager().removeFile(fileToRemove, force=True)
-        gConfigurationData.setOptionInCFG("/DIRAC/Security/UseServerCertificate", "true")
+        if self.cleanWithRMS:
+            res = self.__submitRemovalRequests(fileToRemove, transID)
+        else:
+            # Executing with shifter proxy
+            gConfigurationData.setOptionInCFG("/DIRAC/Security/UseServerCertificate", "false")
+            res = DataManager().removeFile(fileToRemove, force=True)
+            gConfigurationData.setOptionInCFG("/DIRAC/Security/UseServerCertificate", "true")
 
         if not res["OK"]:
             return res
@@ -697,3 +713,51 @@ def __removeWMSTasks(self, transJobIDs):
             return S_ERROR("Failed to remove all the request from RequestDB")
         self.log.info("Successfully removed all the associated failover requests")
         return S_OK()
+
+    def __submitRemovalRequests(self, lfns, transID=0):
+        """Create removal requests for given lfns.
+
+        :param list lfns: list of lfns to be removed
+        :param int transID: transformationID, only used in RequestName
+        :returns: S_ERROR/S_OK
+        """
+        for index, lfnList in enumerate(breakListIntoChunks(lfns, 300)):
+            oRequest = Request()
+            requestName = "TCA_{transID}_{index}_{md5(repr(time.time())).hexdigest()[:5]}"
+            oRequest.RequestName = requestName
+            oOperation = Operation()
+            oOperation.Type = "RemoveFile"
+            oOperation.TargetSE = "All"
+            resMeta = self.metadataClient.getFileMetadata(lfnList)
+            if not resMeta["OK"]:
+                self.log.error("Cannot get file metadata", resMeta["Message"])
+                return resMeta
+            if resMeta["Value"]["Failed"]:
+                self.log.warning(
+                    "Could not get the file metadata of the following, so skipping them:", resMeta["Value"]["Failed"]
+                )
+
+            for lfn, lfnInfo in resMeta["Value"]["Successful"].items():
+                rarFile = File()
+                rarFile.LFN = lfn
+                rarFile.ChecksumType = "ADLER32"
+                rarFile.Size = lfnInfo["Size"]
+                rarFile.Checksum = lfnInfo["Checksum"]
+                rarFile.GUID = lfnInfo["GUID"]
+                oOperation.addFile(rarFile)
+
+            oRequest.addOperation(oOperation)
+            isValid = RequestValidator().validate(oRequest)
+            if not isValid["OK"]:
+                self.log.error("Request is not valid:", isValid["Message"])
+                return isValid
+            result = self.reqClient.putRequest(oRequest)
+            if not result["OK"]:
+                self.log.error("Failed to submit Request: ", result["Message"])
+                return result
+            self.log.info(
+                "RemoveFiles request %d submitted for %d LFNs" % (result["Value"], len(resMeta["Value"]["Successful"]))
+            )
+
+        # after the for loop
+        return S_OK()
diff --git a/src/DIRAC/TransformationSystem/ConfigTemplate.cfg b/src/DIRAC/TransformationSystem/ConfigTemplate.cfg
index 6ad3a6f3de3..f3dbbce2d72 100644
--- a/src/DIRAC/TransformationSystem/ConfigTemplate.cfg
+++ b/src/DIRAC/TransformationSystem/ConfigTemplate.cfg
@@ -109,6 +109,10 @@ Agents
     # using the transformation owner for cleanup
     shifterProxy=
 
+    # If enabled, remove files by submitting requests to the RequestManagementSystem
+    # instead of during the agent run
+    CleanWithRMS=False
+
     # Which transformation types to clean
     # If not filled, transformation types are taken from
     #   Operations/Transformations/DataManipulation